6-BROMO-TETRAL-1-ON
- CAS No.
- 66361-67-9
- Chemical Name:
- 6-BROMO-TETRAL-1-ON
- Synonyms
- 6-Bromotetral-1-one;6-Bromo-1-tetralone;6-bromotetralin-1-one;6-BROMOTETRALONE;6-BROMO-A-TETRALONE;6-BROMO-TETRAL-1-ON;6-Bromo-1-tertralone;6-BROMO-1-TETRALONE,96%;1(2H)-Naphthalenone, 6-broMo-3,4-dihydro-
- CBNumber:
- CB5254662
- Molecular Formula:
- C10H9BrO
- Molecular Weight:
- 225.08
- MDL Number:
- MFCD04114378
- MOL File:
- 66361-67-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 6-BROMO-3,4-DIHYDRO-1(2H)-NAPHTHALENONE AldrichCPR | T263710 | 5MG | $121 |
| 6-Bromo-1-tetralone >95.0%(GC) | B4841 | 1g | $125 |
| 6-Bromo-1-tetralone >95.0%(GC) | B4841 | 5g | $426 |
| 6-Bromo-tetral-1-one | FB52116 | 10g | $900 |
| 6-Bromo-tetral-1-one | FB52116 | 25g | $908.5 |
| More product size | |||
| Melting point | 40-42℃ |
|---|---|
| Boiling point | 116°C/0.05mmHg(lit.) |
| Density | 1.511±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Toluene |
| form | powder to lump |
| color | White to Orange to Green |
| Sensitive | Light Sensitive |
| InChI | InChI=1S/C10H9BrO/c11-8-4-5-9-7(6-8)2-1-3-10(9)12/h4-6H,1-3H2 |
| InChIKey | OSDHOOBPMBLALZ-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=C(Br)C=C2)CCC1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| HS Code | 2914790090 | |||||||||
| NFPA 704 |
|
6-BROMO-TETRAL-1-ON price More Price(78)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T263710 | 6-BROMO-3,4-DIHYDRO-1(2H)-NAPHTHALENONE AldrichCPR | 66361-67-9 | 5MG | $121 | 2026-04-30 | Buy |
| TCI Chemical | B4841 | 6-Bromo-1-tetralone >95.0%(GC) | 66361-67-9 | 1g | $125 | 2026-04-30 | Buy |
| TCI Chemical | B4841 | 6-Bromo-1-tetralone >95.0%(GC) | 66361-67-9 | 5g | $426 | 2026-04-30 | Buy |
| Biosynth | FB52116 | 6-Bromo-tetral-1-one | 66361-67-9 | 10g | $900 | 2026-06-04 | Buy |
| Biosynth | FB52116 | 6-Bromo-tetral-1-one | 66361-67-9 | 25g | $908.5 | 2026-06-04 | Buy |
6-BROMO-TETRAL-1-ON Chemical Properties,Uses,Production
Uses
6-bromo-1-tetralone used in Wittig-Horner reaction.
Synthesis
3470-53-9
66361-67-9
The general procedure for the synthesis of 6-bromo-3,4-dihydronaphthalen-1(2H)-one from 6-amino-1,2,3,4-tetrahydro-1-naphthalenone was as follows: an aqueous solution (10 mL) of NaNO2 (2.35 g, 34 mmol) was added slowly and dropwise at 0°C to a 6-amino-1,2,3,4-tetrahydronaphthalen-1-one (5.0 g, 31 mmol) in a 25% HBr (16 mL) solution. Subsequently, the resulting suspension was transferred to a stirred mixture of 48% HBr (30 mL) of CuBr (8.9 g, 62 mmol) at 0 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 1 hour. After completion of the reaction, the mixture was extracted with EtOAc and the organic phase was dried and concentrated with Na2SO4. The residue was purified by silica gel column chromatography (elution gradient: 0%-60% EtOAc/Hex) to afford 5.6 g (80% yield) of 6-bromo-3,4-dihydronaphthalen-1(2H)-one as a light yellow oil.1H NMR (400 MHz, CDCl3) δ: 2.10-2.16 (2H, m), 2.64 (2H, t, J = 6.4 Hz), 2.94 (2H, t, J = 6.0 Hz), 7.42 (1H, s), 7.44 (1H, s), 7.87 (1H, d, J = 8.9 Hz). Mass spectral analysis: [M + H]+ calculated value C10H9BrO: 225,227; measured value: 225,227.
References
[1] ACS Medicinal Chemistry Letters, 2016, vol. 7, # 4, p. 391 - 396
[2] Chemistry - A European Journal, 2018, vol. 24, # 50, p. 13150 - 13157
[3] Patent: WO2018/183370, 2018, A2. Location in patent: Paragraph 00136
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 5, p. 1284 - 1304
[5] Chemical and Pharmaceutical Bulletin, 1984, vol. 32, # 1, p. 130 - 151
6-BROMO-TETRAL-1-ON Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Synbest Biotech(Hangzhou) Co., Ltd | 86-571-88737065 | sales@synbestech.com | CHINA | 170 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 938 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8741 | 58 |
View Lastest Price from 6-BROMO-TETRAL-1-ON manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | 6-BROMO-TETRAL-1-ON
66361-67-9
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-09-25 | 6-Bromo-3,4-dihydro-1(2H)-naphthalenone
66361-67-9
|
$1.00-200.00 | 1KG | 99%, 99.5% Sublimated | Henan Fengda Chemical Co., Ltd | ||
 |
2020-01-05 | 6-BROMO-TETRAL-1-ON
66361-67-9
|
$1.00 | 1KG | 99% | 1kg-1000kg | Career Henan Chemical Co |
-
- 6-BROMO-TETRAL-1-ON
66361-67-9
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- 6-Bromo-3,4-dihydro-1(2H)-naphthalenone
66361-67-9
- $1.00-200.00
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- 6-BROMO-TETRAL-1-ON
66361-67-9
- $1.00
- 99%
- Career Henan Chemical Co
66361-67-9(6-BROMO-TETRAL-1-ON)Related Search:
1of3
