6-Bromomethyl-nicotinonitrile
- CAS No.
- 158626-15-4
- Chemical Name:
- 6-Bromomethyl-nicotinonitrile
- Synonyms
- 6-Bromomethy1-micotinonitrile;6-Bromomethyl-nicotinonitrile;2-(Bromomethyl)-5-cyanopyridine;6-(bromomethyl)pyridine-3-carbonitrile;2-(Bromomethyl)pyridine-5-carbonitrile;3-Pyridinecarbonitrile, 6-(bromomethyl)-;6-Bromomethyl-nicotinonitrile ISO 9001：2015 REACH
- CBNumber:
- CB52554492
- Molecular Formula:
- C7H5BrN2
- Molecular Weight:
- 197.03
- MDL Number:
- MFCD11227190
- MOL File:
- 158626-15-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H302-H332-H312-H318-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P261-P271-P304+P340-P312-P280-P305+P351+P338-P310 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
6-Bromomethyl-nicotinonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR345474 | 2-(Bromomethyl)-5-cyanopyridine 90% | 158626-15-4 | 250mg | $195 | 2026-06-04 | Buy |
| Activate Scientific | AS39915 | 6-(Bromomethyl)nicotinonitrile 97% | 158626-15-4 | 1g | $281 | 2026-06-04 | Buy |
| Apolloscientific | OR345474 | 2-(Bromomethyl)-5-cyanopyridine 90% | 158626-15-4 | 1g | $373 | 2026-06-04 | Buy |
| Activate Scientific | AS39915 | 6-(Bromomethyl)nicotinonitrile 97% | 158626-15-4 | 5g | $697 | 2026-06-04 | Buy |
| Matrix Scientific | 058787 | 6-Bromomethyl-nicotinonitrile | 158626-15-4 | 50.00mg | $52 | 2026-05-18 | Buy |
6-Bromomethyl-nicotinonitrile Chemical Properties, Uses, Production
Uses
6-(Bromomethyl)nicotinonitrile has been used as a reactant in the synthesis of oxadiazoles as selective S1P receptor agonists that may be used in the treatment of relapsing forms of MS.
Synthesis
3222-48-8
158626-15-4
Example 50 General procedure for the preparation of 6-bromomethylnicotinonitrile (11-2): to a solution of 6-methylnicotinonitrile (11-1) (15 g, 127 mmol) in carbon tetrachloride (300 mL) was added N-bromosuccinimide (27.12 g, 152.4 mmol). The reaction mixture was degassed and displaced three times with nitrogen, followed by the addition of AIBN (2,2'-azobisisobutyronitrile) (2.08 g, 12.6 mmol). After stirring the reaction at 85 °C for 7 h, AIBN (1.04 g) was added and the reaction was continued for 1 h. The reaction was completed with the addition of AIBN (2,2'-Azobisisobutyronitrile). After completion of the reaction, the solvent was removed by distillation under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent being a mixed solvent of ethyl acetate/hexane to give 10 g of the target product 6-bromomethylnicotinonitrile in 40% yield.
References
[1] Patent: WO2007/28083, 2007, A2. Location in patent: Page/Page column 74-75
[2] Inorganic Chemistry, 2014, vol. 53, # 15, p. 7824 - 7836
[3] Patent: WO2016/201052, 2016, A1. Location in patent: Page/Page column 265
[4] Patent: WO2013/102145, 2013, A1. Location in patent: Paragraph 0351
[5] Patent: US2015/344483, 2015, A1. Location in patent: Paragraph 0649; 0650
6-Bromomethyl-nicotinonitrile Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
6-Bromomethyl-nicotinonitrile Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| shanghai aokchem co., ltd | 021-68712331 39130253 | aokchem@gmail.com | China | 332 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| NINGBO INNO PHARMCHEM CO.,LTD. | 86-574-27787657 | info@dearchem.com | China | 4607 | 58 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. | 02161555100 | China | 820 | 58 | |
| Shanghai Kahn Pharmaceutical Co., Ltd. | 021-34979681; 17701870669 | 41513101@qq.com | China | 1789 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Dezhou LonWel Pharmaceutical Technology Co., Ltd. | 13761310616 | 39324283@qq.com | China | 1365 | 58 |
View Latest Price from 6-Bromomethyl-nicotinonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | 6-Bromomethyl-nicotinonitrile
158626-15-4
|
$9.00 | 1KG | 99.8% | 100tons | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 6-Bromomethyl-nicotinonitrile
158626-15-4
- $9.00
- 99.8%
- Hebei Chuanghai Biotechnology Co,.LTD
