ChemicalBook >> CAS DataBase List >>Guanylate Cyclase α subunit (soluble) Polyclonal Antibody

Guanylate Cyclase α subunit (soluble) Polyclonal Antibody

CAS No.
Chemical Name:
Guanylate Cyclase α subunit (soluble) Polyclonal Antibody
Synonyms
Guanylate Cyclase α subunit (soluble) Polyclonal Antibody
CBNumber:
CB52591185
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2025-08-20 16:56:16

Guanylate Cyclase α subunit (soluble) Polyclonal Antibody price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 160895 Guanylate Cyclase α subunit (soluble) Polyclonal Antibody 1ea $347 2026-04-30 Buy
Product number Packaging Price Buy
160895 1ea $347 Buy

Guanylate Cyclase α subunit (soluble) Polyclonal Antibody Chemical Properties, Uses, Production

Description

Soluble guanylate cyclase is a heterodimeric enzyme, composed of α and β subunits, that synthesizes cGMP from GTP. The enzyme is activated by the binding of nitric oxide or carbon monoxide to the heme group of the enzyme. Chronic hypoxia upregulates soluble guanylate expression in rat lung. The α1 subunit contains 690-717 amino acids and has a molecular mass of 77-82 kDa. The cloned β1 subunit of guanylate cyclase from human, bovine, and rat sources contains 619 amino acids and has a molecular mass of approximately 70,000.

References

[1] JAMES R. STONE  Michael A M. Soluble Guanylate Cyclase from Bovine Lung: Activation with Nitric Oxide and Carbon Monoxide and Spectral Characterization of the Ferrous and Ferric States[J]. Biochemistry Biochemistry, 1994, 33 18: 5636-5640. DOI: 10.1021/bi00184a036
[2] D LI  R A J  N Zhou. Soluble guanylate cyclase gene expression and localization in rat lung after exposure to hypoxia.[J]. American Journal of Physiology, 1999, 277 4: L841-7. DOI: 10.1152/ajplung.1999.277.4.l841
[3] GALICIA GIUILI. Molecular cloning of the cDNAs coding for the two subunits of soluble guanylyl cyclase from human brain[J]. FEBS Letters, 1992, 304 1: Pages 83-88. DOI: 10.1016/0014-5793(92)80594-7
[4] M. NAKANE. Molecular cloning and expression of cDNAs coding for soluble guanylate cyclase from rat lung.[J]. The Journal of Biological Chemistry, 1990, 184 1: 16841-16845. DOI: 10.1016/s0021-9258(17)44837-x
[5] MYUNG HO LEE  Robert M B. Supplementation of the phosphatidyl-L-serine requirement of protein kinase C with nonactivating phospholipids[J]. Biochemistry Biochemistry, 1992, 31 22: 5176-5182. DOI: 10.1021/bi00137a013
[6] DORIS KOESLING . The primary structure of the 70 kDa subunit of bovine soluble guanylate cyclase[J]. FEBS Letters, 1988, 239 1: Pages 29-34. DOI: 10.1016/0014-5793(88)80539-8
[7] MASAKI NAKANE . Molecular cloning of a cDNA coding for 70 kilodalton subunit of soluble guanylate cyclase from rat lung[J]. Biochemical and biophysical research communications, 1988, 157 3: Pages 1139-1147. DOI: 10.1016/s0006-291x(88)80992-6

Guanylate Cyclase α subunit (soluble) Polyclonal Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

Guanylate Cyclase α subunit (soluble) Polyclonal Antibody Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
Cayman Chemical Company -- cayman@caymanchem.com United States 6987 81
Supplier Advantage
Cayman Chemical Company 81
Guanylate Cyclase α subunit (soluble) Polyclonal Antibody