5,7-dichloroiMidazo[1,2-c]pyriMidine
- CAS No.
- 85989-61-3
- Chemical Name:
- 5,7-dichloroiMidazo[1,2-c]pyriMidine
- Synonyms
- 5,7-dichloroiMidazo[1,2-c]pyriMidine;Imidazo[1,2-c]pyrimidine, 5,7-dichloro-
- CBNumber:
- CB52598098
- Molecular Formula:
- C6H3Cl2N3
- Molecular Weight:
- 188.01
- MDL Number:
- MFCD13189631
- MOL File:
- 85989-61-3.mol
- MSDS File:
- SDS
| Density | 1.69±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 1.91±0.30(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChI | InChI=1S/C6H3Cl2N3/c7-4-3-5-9-1-2-11(5)6(8)10-4/h1-3H |
| InChIKey | QMTXTHVMSRFISO-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC(Cl)=CC2=NC=CN12 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P301+P312-P362+P364 |
| HS Code | 2933998090 |
5,7-dichloroiMidazo[1,2-c]pyriMidine price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR946694 | 5,7-Dichloroimidazo[1,2-c]pyrimidine 97% | 85989-61-3 | 100mg | $25 | 2026-06-04 | Buy |
| Apolloscientific | OR946694 | 5,7-Dichloroimidazo[1,2-c]pyrimidine 97% | 85989-61-3 | 250mg | $49 | 2026-06-04 | Buy |
| Apolloscientific | OR946694 | 5,7-Dichloroimidazo[1,2-c]pyrimidine 97% | 85989-61-3 | 1g | $111 | 2026-06-04 | Buy |
| Apolloscientific | OR946694 | 5,7-Dichloroimidazo[1,2-c]pyrimidine 97% | 85989-61-3 | 5g | $400 | 2026-06-04 | Buy |
| Matrix Scientific | 221404 | 5,7-Dichloroimidazo[1,2-c]pyrimidine | 85989-61-3 | 250.00mg | $47 | 2026-05-18 | Buy |
5,7-dichloroiMidazo[1,2-c]pyriMidine Chemical Properties, Uses, Production
Synthesis
56817-09-5
85989-61-3
General procedure for the synthesis of 5,7-dichloroimidazo[1,2-c]pyrimidines from 7-chloroimidazo[1,2-c]pyrimidin-5(6H)-ones: 38.3 g (225.86 mmol) of 7-chloroimidazo[1,2-c]pyrimidin-5(6H)-one was suspended in 450.2 g (2936 mmol) of phosphorochloridic acid chloride under argon protection. The reaction mixture was heated to 120°C for 4 hours. Upon completion of the reaction, the excess phosphoryl chloride was evaporated under reduced pressure and the residue was azeotropically distilled with toluene to further remove the residual phosphoryl chloride. The residue was suspended in water and the pH was adjusted to 7 with saturated aqueous sodium bicarbonate and the precipitated solid was collected by filtration. The solid was washed with water and dried for 18 hours using phosphorus pentoxide as the drying agent. Finally 33.5 g of the target product 5,7-dichloroimidazo[1,2-c]pyrimidine was obtained in 67% yield. The product was analyzed by LCMS (Method 6): retention time Rt = 1.01 min, m/z = 189 (M + H)+. 1H-NMR (400 MHz, DMSO-d6) data were as follows: δ= 8.11 (s, 1H), 7.94 (s, 1H), 7.81 (s, 1H).
References
[1] Patent: US2010/113441, 2010, A1. Location in patent: Page/Page column 27
[2] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 1, p. 42 - 46
[3] Patent: US2006/84650, 2006, A1. Location in patent: Page/Page column 87
5,7-dichloroiMidazo[1,2-c]pyriMidine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xinxiang Anqi Biotechnology Co., Ltd | 15036601220 | 877180706@qq.com | China | 57 | 58 |
| Shanghai Synthfine Chemical Co.,Ltd | 15921303235 | sales@synthfine.com | China | 994 | 58 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9954 | 58 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
View Latest Price from 5,7-dichloroiMidazo[1,2-c]pyriMidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-30 | 5,7-dichloroiMidazo[1,2-c]pyriMidine
85989-61-3
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
![]() |
2022-08-13 | 5,7-dichloroiMidazo[1,2-c]pyriMidine
85989-61-3
|
1G | 98%minHPLC | 50kg/month | Shanghai Rlavie Technology Co ltd |
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![5,7-dichloroiMidazo[1,2-c]pyriMidine pictures](/ProductImageEN1/2025-06/Small/902a9ae7-cb96-41eb-a78d-21d4c2162aad.png)
- 5,7-dichloroiMidazo[1,2-c]pyriMidine
85989-61-3
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
![5,7-dichloroiMidazo[1,2-c]pyriMidine pictures](/ProductImageEN/2022-09/Small/9e0f4eab-2928-4274-99a2-7043397e2d76.jpg)
- 5,7-dichloroiMidazo[1,2-c]pyriMidine
85989-61-3
- 98%minHPLC
- Shanghai Rlavie Technology Co ltd





