ChemicalBook >> CAS DataBase List >>5,7-dichloroiMidazo[1,2-c]pyriMidine

5,7-dichloroiMidazo[1,2-c]pyriMidine

CAS No.
85989-61-3
Chemical Name:
5,7-dichloroiMidazo[1,2-c]pyriMidine
Synonyms
5,7-dichloroiMidazo[1,2-c]pyriMidine;Imidazo[1,2-c]pyrimidine, 5,7-dichloro-
CBNumber:
CB52598098
Molecular Formula:
C6H3Cl2N3
Molecular Weight:
188.01
MDL Number:
MFCD13189631
MOL File:
85989-61-3.mol
MSDS File:
SDS
Last updated:2026-05-28 03:26:18

5,7-dichloroiMidazo[1,2-c]pyriMidine Properties

Density 1.69±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 1.91±0.30(Predicted)
Appearance Off-white to light yellow Solid
InChI InChI=1S/C6H3Cl2N3/c7-4-3-5-9-1-2-11(5)6(8)10-4/h1-3H
InChIKey QMTXTHVMSRFISO-UHFFFAOYSA-N
SMILES C1(Cl)=NC(Cl)=CC2=NC=CN12

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P280-P301+P312-P362+P364
HS Code  2933998090

5,7-dichloroiMidazo[1,2-c]pyriMidine price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR946694 5,7-Dichloroimidazo[1,2-c]pyrimidine 97% 85989-61-3 100mg $25 2026-06-04 Buy
Apolloscientific OR946694 5,7-Dichloroimidazo[1,2-c]pyrimidine 97% 85989-61-3 250mg $49 2026-06-04 Buy
Apolloscientific OR946694 5,7-Dichloroimidazo[1,2-c]pyrimidine 97% 85989-61-3 1g $111 2026-06-04 Buy
Apolloscientific OR946694 5,7-Dichloroimidazo[1,2-c]pyrimidine 97% 85989-61-3 5g $400 2026-06-04 Buy
Matrix Scientific 221404 5,7-Dichloroimidazo[1,2-c]pyrimidine 85989-61-3 250.00mg $47 2026-05-18 Buy
Product number Packaging Price Buy
OR946694 100mg $25 Buy
OR946694 250mg $49 Buy
OR946694 1g $111 Buy
OR946694 5g $400 Buy
221404 250.00mg $47 Buy

5,7-dichloroiMidazo[1,2-c]pyriMidine Chemical Properties, Uses, Production

Synthesis

7-chloroiMidazo[1,2-c]pyriMidin-5-ol

56817-09-5

5,7-dichloroiMidazo[1,2-c]pyriMidine

85989-61-3

General procedure for the synthesis of 5,7-dichloroimidazo[1,2-c]pyrimidines from 7-chloroimidazo[1,2-c]pyrimidin-5(6H)-ones: 38.3 g (225.86 mmol) of 7-chloroimidazo[1,2-c]pyrimidin-5(6H)-one was suspended in 450.2 g (2936 mmol) of phosphorochloridic acid chloride under argon protection. The reaction mixture was heated to 120°C for 4 hours. Upon completion of the reaction, the excess phosphoryl chloride was evaporated under reduced pressure and the residue was azeotropically distilled with toluene to further remove the residual phosphoryl chloride. The residue was suspended in water and the pH was adjusted to 7 with saturated aqueous sodium bicarbonate and the precipitated solid was collected by filtration. The solid was washed with water and dried for 18 hours using phosphorus pentoxide as the drying agent. Finally 33.5 g of the target product 5,7-dichloroimidazo[1,2-c]pyrimidine was obtained in 67% yield. The product was analyzed by LCMS (Method 6): retention time Rt = 1.01 min, m/z = 189 (M + H)+. 1H-NMR (400 MHz, DMSO-d6) data were as follows: δ= 8.11 (s, 1H), 7.94 (s, 1H), 7.81 (s, 1H).

References

[1] Patent: US2010/113441, 2010, A1. Location in patent: Page/Page column 27
[2] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 1, p. 42 - 46
[3] Patent: US2006/84650, 2006, A1. Location in patent: Page/Page column 87

5,7-dichloroiMidazo[1,2-c]pyriMidine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 64)
Supplier Tel Email Country ProdList Advantage
Xinxiang Anqi Biotechnology Co., Ltd 15036601220 877180706@qq.com China 57 58
Shanghai Synthfine Chemical Co.,Ltd 15921303235 sales@synthfine.com China 994 58
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3996 55
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9954 58
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60

View Latest Price from 5,7-dichloroiMidazo[1,2-c]pyriMidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5,7-dichloroiMidazo[1,2-c]pyriMidine pictures 2026-06-30 5,7-dichloroiMidazo[1,2-c]pyriMidine
85989-61-3
1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
5,7-dichloroiMidazo[1,2-c]pyriMidine pictures 2022-08-13 5,7-dichloroiMidazo[1,2-c]pyriMidine
85989-61-3
1G 98%minHPLC 50kg/month Shanghai Rlavie Technology Co ltd

5,7-dichloroiMidazo[1,2-c]pyriMidine Spectrum

5,7-dichloroiMidazo[1,2-c]pyriMidine Imidazo[1,2-c]pyrimidine, 5,7-dichloro- 85989-61-3