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BrettPhosPalladacycle

CAS No.
1148148-01-9
Chemical Name:
BrettPhosPalladacycle
Synonyms
BrettPhos Pd G1;BrettPhos precatalyst;BrettPhos Palladacycle;BrettPhos Pd G1 Methyl-t-Butyl Ether Adduct;dicyclohexyl-[3,6-dimethoxy-2-(2,4,6-triisopropylphenyl)phenyl]phosphane;BrettPhos Pd G1 MTBE adduct;BrettPhos Palladacycle Gen. 1;chloro-(2-phenylethylamino)palladium;[2-(2-aminoethyl)phenyl]palladium(1+);(II) Chloro[2-(dicyclohexylphosphino)-3
CBNumber:
CB52614378
Molecular Formula:
C43H63ClNO2PPd
Molecular Weight:
798.81
MDL Number:
MFCD12545956
MOL File:
1148148-01-9.mol
Last updated:2026-05-28 03:39:34
Product description Number Pack Size Price
BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 718750 100 mg $71.81
BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 718750 1 g $384.3
BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 718750 5 g $1490
BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 718750 1g $533
BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 718750 5g $1450
More product size

BrettPhosPalladacycle Properties

Melting point 198-204 °C
storage temp. 2-8°C, protect from light, stored under nitrogen
form Powder
color white
UNSPSC Code 12161600
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26

BrettPhosPalladacycle price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 718750 BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 100 mg $71.81 2025-07-31 Buy
Sigma-Aldrich 718750 BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 1 g $384.3 2025-07-31 Buy
Sigma-Aldrich 718750 BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 5 g $1490 2025-07-31 Buy
Sigma-Aldrich 718750 BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 1148148-01-9 1g $533 2024-03-01 Buy
Sigma-Aldrich 718750 BrettPhos Pd G1, Methyl t-Butyl Ether Adduct may contain up to 1 mole equivalent of MTBE, 97% 1148148-01-9 5g $1450 2024-03-01 Buy
Product number Packaging Price Buy
718750 100 mg $71.81 Buy
718750 1 g $384.3 Buy
718750 5 g $1490 Buy
718750 1g $533 Buy
718750 5g $1450 Buy

BrettPhosPalladacycle Chemical Properties,Uses,Production

Reaction

  1. Catalyst for cross-coupling reactions using aryl mesylates with electron-deficient anilines.
  2. Catalyst for rapid C-N bond-forming processes at low catalyst loading.
  3. Cross-coupling of 3-Bromo-2-aminopyridine with primary amines.
Reactions of 1148148-01-9

Uses

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Catalyst for:

  • C,N-cross coupling of unprotected 3-halo-2-aminopyridines with primary and secondary amines
  • Amination reaction
  • N-arylation of aminophenols

General Description

BrettPhos Pd G1 is a Buchwald first generation (G1) palladacycle precatalyst that can be used in cross-coupling reactions for the formation of C-C, C–N, C–O, C–F, C–CF3, and C–S bonds. The formation of the active Pd(0) species in the G1 precatalyst is easy to generate, requiring merely a deprotonation with a base. The resulting catalyst is very active, even at temperatures down to 40 °C, and can be used in a variety of cross-coupling protocols.

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

BrettPhosPalladacycle Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 101)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16505 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32997 60
Accela ChemBio Inc.
+1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
career henan chemical co
+86-0371-86658258 factory@coreychem.com China 29780 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 3961 58
Richest Group Ltd
18017061086 oled@richest-group.com CHINA 5597 58
QINGDAO KAIENSI INTERNATIONAL TRADE CO.,LTD.
+86-0532-8699-9256 +86-18518128472 kaley@cnfdevelop.com China 1408 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21135 58
Wuhan LPBchem Technology Co.,Ltd
+86-027-63498399 15071314134 LPBchem@163.com CHINA 57 58
Shanghai UCHEM Inc.
+86-18930848214 +86-021-56762820 sales@myuchem.com China 8898 58

View Lastest Price from BrettPhosPalladacycle manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BrettPhosPalladacycle pictures 2026-07-02 BrettPhosPalladacycle
1148148-01-9
$2.00-5.00 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) /BrettPhos Pd G1 pictures 2021-06-11 Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) /BrettPhos Pd G1
1148148-01-9
$10.00 1g 0.98 50kg Wuhan LPBchem Technology Co.,Ltd
Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-aMinoethyl)phenyl]palladiuM(II)   pictures 2020-04-22 Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-aMinoethyl)phenyl]palladiuM(II)
1148148-01-9
$1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2'-4'-6'-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-aMinoethyl)phenyl]palladiuM(II),98% BrettPhos Pd G1 Methyl-t-Butyl Ether Adduct Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aMinoethyl)phenyl]palladiuM(II), Min. 98% [BrettPhos Palladacycle] Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-aminoeth Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-Minoethyl)phenyl]palladiuM(II),Min.98%[BrettPhosPalladacycle] (BrettPhos) palladium(II) phenethylamine chloride BrettPhos Palladacycle Dicyclohexyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine-(2-(2-aminoethyl)phenyl)palladium(II) chloride Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(ii) Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-amino CHLORO[2-(DICYCLOHEXYLPHOSPHINO)-3,6-DIMETHOXY-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL][2-(2-AMINOETHYL)PHENYL]PALLADIUM(II),MIN.98%[BRETTPHOSPALLADACYCLEGEN.1] (SP-4-4)-[2-[2-(Amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine-κP]palladium Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-aMinoethyl)phenyl]palladiuM(II) [BrettPhos Palladacycle] [2-(2-aminoethyl)phenyl]palladium(1+) BrettPhos Palladacycle Gen. 1 Chloride (2-dicyclohexylphosphino-3,6-dimethoxy-2 ', 4', 6 '- triisopropyl-1,1' - biphenyl) [2 - (2-aminoethyl phenyl)] palladium (II) Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) / BrettPhos Pd G1 Palladium, [2-[2-(amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine-κP]-, (SP-4-4)- Chloro[2-(dicyclohexylphosphino)-2',4',6'-triisopropyl-3,6-dimethoxybiphenyl][2-(2-aminoethyl)phenyl]palladium(II) Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-... BrettPhos Pd G1 / Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) chloro-(2-phenylethylamino)palladium Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) BrettPhos Pd G1 MTBE adduct Chloro[2-(dicyclohexylphosphino)-2’,4’,6’-triisopropyl-3,6-dimethoxybiphenyl][2-(2-aminoethyl)phenyl]palladium(II) (II) Chloro[2-(dicyclohexylphosphino)-3 (2-Dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethylphenyl)]palladium(II)chloride,BrettPhosPalladacycleGen.1 BrettPhos Palladacycle Gen. 1 Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) chloro-(2-phenylethylamino)palladium,dicyclohexyl-[3,6-dimethoxy-2-(2,4,6-triisopropylphenyl)phenyl]phosphane BrettPhos precatalyst BrettPhos Pd G1 dicyclohexyl-[3,6-dimethoxy-2-(2,4,6-triisopropylphenyl)phenyl]phosphane 1148148-01-9 C43H63ClNO2PPd C48H74ClNO3PPd Buchwald Ligands&Precatalysts Buchwald Precatalysts Series Pd