3-iodo-1H-indole-5-carbonitrile
- CAS No.
- 1092114-59-4
- Chemical Name:
- 3-iodo-1H-indole-5-carbonitrile
- Synonyms
- 3-iodo-1H-indole-5-carbonitrile;1H-Indole-5-carbonitrile, 3-iodo-
- CBNumber:
- CB52659092
- Molecular Formula:
- C9H5IN2
- Molecular Weight:
- 268.05
- MDL Number:
- MFCD22683211
- MOL File:
- 1092114-59-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933998090 |
3-iodo-1H-indole-5-carbonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR45089 | 3-Iodo-1H-indole-5-carbonitrile 95% | 1092114-59-4 | 1g | $102 | 2026-06-04 | Buy |
| Apolloscientific | OR45089 | 3-Iodo-1H-indole-5-carbonitrile 95% | 1092114-59-4 | 5g | $304 | 2026-06-04 | Buy |
| Apolloscientific | OR45089 | 3-Iodo-1H-indole-5-carbonitrile 95% | 1092114-59-4 | 10g | $491 | 2026-06-04 | Buy |
| Synthonix | K69519 | 3-Iodo-1H-indole-5-carbonitrile >98% | 1092114-59-4 | 1g | $108 | 2026-05-06 | Buy |
| Synthonix | K69519 | 3-Iodo-1H-indole-5-carbonitrile >98% | 1092114-59-4 | 5g | $120 | 2026-05-06 | Buy |
3-iodo-1H-indole-5-carbonitrile Chemical Properties, Uses, Production
Synthesis
15861-24-2
1092114-59-4
Example 1 Synthesis of 3-iodo-1H-indole-5-carbonitrile (V) 1H-indole-5-carbonitrile (5 g, 35.2 mmol), potassium hydroxide (KOH, 7.90 g, 141 mmol) and iodine (I2, 8.90 g, 35.2 mmol) were suspended in 25 mL of N,N-dimethylformamide (DMF) under inert atmosphere. The reaction mixture was stirred at 10 °C for 30 min under light protection, followed by quenching the reaction with 0.1 M sodium thiosulfate (Na2S2O3) solution (150 mL). The resulting suspension was continued to be stirred for 30 min, then filtered, and the collected solid was washed with deionized water and dried under vacuum at 50 °C to constant weight. The final white solid product 3-iodo-1H-indole-5-carbonitrile (V) (9.0 g) was obtained in 95% yield. 1H-NMR (400 MHz, CDCl3) data: δ 8.78 (1H, broad peak); 7.80 (1H, single peak); 7.46-7.40 (3H, multiple peaks).
References
[1] Patent: US2014/275542, 2014, A1. Location in patent: Paragraph 0060; 0061
[2] Patent: WO2012/129338, 2012, A1. Location in patent: Page/Page column 192-193
[3] Patent: EP2163554, 2010, A1. Location in patent: Page/Page column 107
[4] Organic Letters, 2013, vol. 15, # 12, p. 2982 - 2985
[5] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 15, p. 4031 - 4033
3-iodo-1H-indole-5-carbonitrile Preparation Products And Raw materials
3-iodo-1H-indole-5-carbonitrile Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai potentpharm CO.,Ltd | 13524892556 | sales-cn@potentpharm.com | China | 1011 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Anmike Chemical Co. Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 9988 | 55 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 13611835272 13611835272 | mmwang@sunwaypharm.com | China | 44090 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39796 | 58 |
| Beijing Stronger Science Co., Ltd. | 0531-88924771 15614660963 | elsa.hang@strongerscience.com | China | 10622 | 58 |
| Hefei Mokai Pharmaceutical Technology Co., Ltd | 18130062233 | 690231469@qq.com | China | 8000 | 58 |
| Bide Pharmatech Ltd. | 400-6005915 | sales@picasso-e.com | China | 39662 | 58 |
