4,6-Dimethyl-1-indanone
- CAS No.
- 1685-81-0
- Chemical Name:
- 4,6-Dimethyl-1-indanone
- Synonyms
- 4,6-Dimethyl-2,3-dihydro-1H-inden-1-one;4,6-Dimethyl-1-indanone;4,6-Dimethyl-indan-1-one;1H-inden-1-one, 2,3-dihydro-4,6-dimethyl-;(S)-2-amino-3-(4-(prop-2-yn-1-yl)phenyl)propanoic acid
- CBNumber:
- CB52684809
- Molecular Formula:
- C11H12O
- Molecular Weight:
- 160.21
- MDL Number:
- MFCD09908137
- MOL File:
- 1685-81-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
4,6-Dimethyl-1-indanone price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS110843 | 4,6-Dimethyl-2,3-dihydro-1H-inden-1-one 97% | 1685-81-0 | 1g | $86 | 2026-06-04 | Buy |
| Activate Scientific | AS110843 | 4,6-Dimethyl-2,3-dihydro-1H-inden-1-one 97% | 1685-81-0 | 5g | $255 | 2026-06-04 | Buy |
| Activate Scientific | AS110843 | 4,6-Dimethyl-2,3-dihydro-1H-inden-1-one 97% | 1685-81-0 | 25g | $786 | 2026-06-04 | Buy |
| Synthonix | D54543 | 4,6-Dimethyl-2,3-dihydro-1H-inden-1-one 97% | 1685-81-0 | 100mg | $44 | 2026-05-06 | Buy |
| Synthonix | D54543 | 4,6-Dimethyl-2,3-dihydro-1H-inden-1-one 97% | 1685-81-0 | 250mg | $48 | 2026-05-06 | Buy |
4,6-Dimethyl-1-indanone Chemical Properties, Uses, Production
Synthesis
1811-85-4
1685-81-0
To 3-(2,4-dimethylphenyl)propionic acid (5.63 g, 14.4 mmol) was added polyphosphoric acid (138 g) and the mixture was stirred at 90 °C for 1 hour. Upon completion of the reaction, the reaction solution was poured into ice water to quench the reaction and the organic phase was extracted with dichloromethane. The organic layer was washed sequentially with water and saturated sodium chloride solution, followed by drying with anhydrous magnesium sulfate and filtration. The solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography (eluent ratio: hexane/ethyl acetate = 100:0 to 0:100, v/v) to afford the target compound 4,6-dimethyl-2,3-dihydro-1H-inden-1-one as a white solid (4.62 g, yield: 91%).1H NMR (CDCl3, 400 MHz) data were as follows: δ2.32 (3H, s ), 2.37 (3H, s), 2.68-2.71 (2H, m), 2.96-2.99 (2H, m), 7.24 (1H, s), 7.40 (1H, s).
References
[1] Patent: US2011/53974, 2011, A1. Location in patent: Page/Page column 78-79
[2] Bulletin de la Societe Chimique de France, 1965, p. 785 - 787
[3] Bulletin de la Societe Chimique de France, 1970, p. 1466 - 1473
[4] Louvain Medical, 1974, vol. 93, # 4, p. 189 - 194
[5] Journal of Heterocyclic Chemistry, 1987, vol. 24, # 3, p. 677 - 682
4,6-Dimethyl-1-indanone Preparation Products And Raw materials
4,6-Dimethyl-1-indanone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NINGBO INNO PHARMCHEM CO.,LTD. | 86-574-27787657 | info@dearchem.com | China | 4607 | 58 |
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