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SPhos Pd G2

CAS No.
1375325-64-6
Chemical Name:
SPhos Pd G2
Synonyms
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)[2-(2'-amino-1,1'-biphenyl)]palladium(II);RK1001022;SPhos Pd G2;SPhos Pd G2 catalyst;SPhos Pd G2 ChemBeads;SPhos Palladacycle Gen.2;SPhos Pd G2 ISO 9001:2015 REACH;2nd Generation SPhos Precatalyst;Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl...;[2′-(Amino-κN)[1,1′-biphenyl]-2-yl-κC]chloro[dicyclohexyl(2′,6′-dimethoxy[1,1′-b…
CBNumber:
CB52686111
Molecular Formula:
C38H45ClNO2PPd
Molecular Weight:
720.63
MDL Number:
MFCD20264897
MOL File:
1375325-64-6.mol
MSDS File:
SDS
Last updated:2026-01-13 11:19:16
Product description Number Pack Size Price
SPhos Pd G2 753009 1g $197
SPhos Pd G2 753009 5g $627
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl) palladium(II) min. 98% [SPhos Palladacycle Gen. 2] min.98% 46-0283 250mg $41
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl) palladium(II) min. 98% [SPhos Palladacycle Gen. 2] min.98% 46-0283 1g $124
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl) palladium(II) min. 98% [SPhos Palladacycle Gen. 2] min.98% 46-0283 5g $473
More product size

SPhos Pd G2 Properties

Melting point 218°C (dec.)
storage temp. 2-8°C, protect from light, stored under nitrogen
form Powder
color white
InChIKey PYMQIHHZINPLDV-UHFFFAOYSA-N
SMILES P(C1CCCCC1)(C1CCCCC1)(C1C=CC=CC=1C1C(=CC=CC=1OC)OC)[Pd+2]1(NC2=CC=CC=C2C2=CC=CC=[C-]12)[Cl-]
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

WGK Germany  3
Storage Class 11 - Combustible Solids

SPhos Pd G2 price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 753009 SPhos Pd G2 1375325-64-6 1g $197 2026-04-30 Buy
Sigma-Aldrich 753009 SPhos Pd G2 1375325-64-6 5g $627 2026-04-30 Buy
Strem Chemicals 46-0283 Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl) palladium(II) min. 98% [SPhos Palladacycle Gen. 2] min.98% 1375325-64-6 250mg $41 2026-04-30 Buy
Strem Chemicals 46-0283 Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl) palladium(II) min. 98% [SPhos Palladacycle Gen. 2] min.98% 1375325-64-6 1g $124 2026-04-30 Buy
Strem Chemicals 46-0283 Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl) palladium(II) min. 98% [SPhos Palladacycle Gen. 2] min.98% 1375325-64-6 5g $473 2026-04-30 Buy
Product number Packaging Price Buy
753009 1g $197 Buy
753009 5g $627 Buy
46-0283 250mg $41 Buy
46-0283 1g $124 Buy
46-0283 5g $473 Buy

SPhos Pd G2 Chemical Properties,Uses,Production

Reactions

Palladium precatalyst for Suzuki-Miyaura coupling reactions. Reactions of 1375325-64-6

Uses

Application in Suzuki-Miyaura coupling:

  • Self-arylation of 1-alkyl-3-bromo-2-phenyl-2,1-borazaronaphthalenes to form 2,1-borazaronaphthols.
  • Suzuki–Miyaura coupling of [Ru(bpy)2]+ with 4-carboxyphenylboronic acid.
  • Suzuki–Miyaura coupling of β-borylated porphyrins with 2-iodoaniline.

General Description

SPhos Pd G2 is a second generation (G2) precatalyst in which phenethylamine based backbone of the (G1) complex is substituted with a biphenyl-based ligand. This improvement on the previous generation allows creating the active palladium species at room temperature with weak phosphate or carbonate bases. The catalyst proves remarkably adept at achieving a variety of Suzuki-Miyaura couplings among other cross-coupling reactions.

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

SPhos Pd G2 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 124)Suppliers
Supplier Tel Email Country ProdList Advantage
XINXIANG RUNYU MATERIAL CO., LTD.
+86-13592593621; +8613592593621 sales@runvmat.com China 457 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16513 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13901 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 21193 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
Richest Group Ltd
18017061086 oled@richest-group.com CHINA 5600 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5742 58

View Lastest Price from SPhos Pd G2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SPhos Pd G2 pictures 2026-04-17 SPhos Pd G2
1375325-64-6
$2.00-5.00 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
SPhos Pd G2  pictures 2025-11-18 SPhos Pd G2
1375325-64-6
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) / SPhos Pd G2 pictures 2021-06-11 Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) / SPhos Pd G2
1375325-64-6
$10.00 1g 0.98 50kg Wuhan LPBchem Technology Co.,Ltd
  • SPhos Pd G2 pictures
  • SPhos Pd G2
    1375325-64-6
  • $2.00-5.00
  • 99%
  • ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
  • SPhos Pd G2  pictures
  • SPhos Pd G2
    1375325-64-6
  • $1.10
  • 99.00%
  • Dideu Industries Group Limited
SPhos Pd G2 2nd Generation SPhos Precatalyst chloropalladium(1+),dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphane,2-phenylaniline RK1001022 Chloro(2-dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl)(2'-aMino-1,1'-biphenyl-2-yl) palladiuM(II), Min. 98% [SPhos Palladacycle] Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) CHLORO(2-DICYCLOHEXYLPHOSPHINO-2',6'-DIMETHOXY-1,1'-BIPHENYL)(2'-AMINO-1,1'-BIPHENYL-2-YL)PALLADIUM(II)MIN.98%[SPHOSPALLADACYCLEGEN.2] SPhos Palladacycle Gen.2 SPhos Pd G2 catalyst Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) / SPhos Pd G2 SPhos Pd G2 ISO 9001:2015 REACH Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl... SPhos Pd G2 / Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)[2-(2'-amino-1,1'-biphenyl)]palladium(II) (SPhos Pd G2) Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl) palladium(II) min. Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl) palladium(II) SPhos Pd G2 ChemBeads Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II),SPhosPalladacycleGen.2 [2′-(Amino-κN)[1,1′-biphenyl]-2-yl-κC]chloro[dicyclohexyl(2′,6′-dimethoxy[1,1′-b… chloro(2-dicyclohexylphosphinoyl-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)paladium(I-I) Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)[2-(2'-amino-1,1'-biphenyl)]palladium(II) 1375325-64-6 C38H45ClNO2PPd C26H35O2PC12H10ClNPd Buchwald Ligands&Precatalysts Buchwald Precatalysts Series Pd