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ChemicalBook >> CAS DataBase List >>2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde Structure
2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde structure
CAS No.
1185428-32-3
Chemical Name:
2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde
Synonyms
2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-car;2-broMo-5h-pyrrolo[2,3-b]pyrazine-7-carbaldehyde;2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde;5H-Pyrrolo[2,3-b]pyrazine-7-carboxaldehyde, 2-bromo-
CBNumber:
CB52704187
Molecular Formula:
C7H4BrN3O
Molecular Weight:
226.03
MDL Number:
MFCD17015976
MOL File:
1185428-32-3.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:42
Product description Number Pack Size Price
2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde B712020 50mg $155
2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 95+% CD11338165 250mg $235
2-bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 95%+ CM104160 250mg $255
2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 95+% CD11338165 1g $498
2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 1185428323 1g $539.28
Request For Quotation

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
Appearance Light yellow to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2933998090

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B712020 2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 1185428-32-3 50mg $155 2021-12-16 Buy
Crysdot CD11338165 2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 95+% 1185428-32-3 250mg $235 2021-12-16 Buy
Chemenu CM104160 2-bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 95%+ 1185428-32-3 250mg $255 2021-12-16 Buy
Crysdot CD11338165 2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 95+% 1185428-32-3 1g $498 2021-12-16 Buy
Alichem 1185428323 2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 1185428-32-3 1g $539.28 2021-12-16 Buy
Product number Packaging Price Buy
B712020 50mg $155 Buy
CD11338165 250mg $235 Buy
CM104160 250mg $255 Buy
CD11338165 1g $498 Buy
1185428323 1g $539.28 Buy

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde Chemical Properties,Uses,Production

Synthesis

(2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)methanol

1334674-88-2

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde

1185428-32-3

Step 3. Synthesis of 2-bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde. To a suspension of 2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-ylmethanol (127 g, 562 mmol) in acetone (2.5 L), Jones reagent (253 mL, 674 mmol) was slowly added dropwise. After the dropwise addition, the reaction mixture was stirred at room temperature for 50 min, and gradual clarification of the suspension and precipitation of a brown solid was observed.Preparation of Jones' reagent (2.67 M) required the careful addition of concentrated H2SO4 (184 mL) to CrO3 (213.6 g) at less than 10 °C, followed by dilution with H2O up to 800 mL.Upon completion of the reaction, the reaction was quenched with isopropanol ( 60 mL) to quench the reaction and the solid was separated by filtration. The filter cake was washed with acetone (1L x 2), and the filtrates were combined and concentrated to afford the target product 2-bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde (320 g, 84.4% yield) as a yellow solid.

References

[1] Journal of Medicinal Chemistry, 2013, vol. 56, # 1, p. 345 - 356
[2] Patent: US2015/158864, 2015, A1. Location in patent: Paragraph 0650
[3] Patent: WO2016/178110, 2016, A1. Location in patent: Page/Page column 30
[4] Patent: US2011/230462, 2011, A1. Location in patent: Page/Page column 54; 56
[5] Patent: WO2011/144584, 2011, A1. Location in patent: Page/Page column 37

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde Preparation Products And Raw materials

Raw materials

5-Bromo-4,7-diazaindole (2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)methanol Hexamethylenetetramine Acetone EDTA methidiumpropylamide

Preparation Products

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
NINGBOBENKANGJS PHARMTECHCO., LTD 		+8615990591583 15990591583 CHINA 2029 58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		+8618795957998 karmelhk@126.com CHINA 2886 58
CR Corporation Limited 		+8613062833949 fred.wen@crcorporation.cn China 8645 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658 sales1@artkmedchem.com China 39002 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39927 58
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Chengdu Feibo Pharm Technology Co., Ltd +86 028-84641798 15982321820 abby@arkpharm.com China 10000 58
Supplier Advantage
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
NINGBOBENKANGJS PHARMTECHCO., LTD 		58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		58
CR Corporation Limited 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Aladdin Scientific 		58
Suzhou ARTK Medchem Co., Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Amadis Chemical Company Limited 		58
Chengdu Feibo Pharm Technology Co., Ltd 58

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde Spectrum

2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde(1185428-32-3)1HNMR
2-BroMo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde 2-broMo-5h-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 5H-Pyrrolo[2,3-b]pyrazine-7-carboxaldehyde, 2-bromo- 2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-car 1185428-32-3