2-Methyl-1,3-cyclopentanedione
- CAS No.
- 765-69-5
- Chemical Name:
- 2-Methyl-1,3-cyclopentanedione
- Synonyms
- 1,3-Cyclopentanedione, 2-methyl-;2-Methylcyclopentane-1,3-dione;2-Methyl-1,3-cyclopentadione;-1,3-cycL;2-Methyl-1;METHYLCYCLE-D;2-Methylcyclopentan-1,3-dion;2-METHYLCYCLOPENTAN-1,3-DIONE;2-Methyl-1,3-dioxocyclopentane;2-METHYL-1,3-CYCLOPENTANEDIONE
- CBNumber:
- CB5272422
- Molecular Formula:
- C6H8O2
- Molecular Weight:
- 112.13
- MDL Number:
- MFCD00001406
- MOL File:
- 765-69-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Methyl-1,3-cyclopentanedione 99% | 117021 | 5g | $28.5 |
| 2-Methyl-1,3-cyclopentanedione 99% | 117021 | 25g | $61.5 |
| 2-Methyl-1,3-cyclopentanedione for synthesis | 8.10504 | 10g | $64.1 |
| 2-Methyl-1,3-cyclopentanedione >97.0%(GC)(T) | M0901 | 5g | $35 |
| 2-Methyl-1,3-cyclopentanedione >97.0%(GC)(T) | M0901 | 25g | $95 |
| More product size | |||
| Melting point | 212-215 °C (lit.) |
|---|---|
| Boiling point | 213°C (estimate) |
| Density | 1.0795 (rough estimate) |
| refractive index | 1.4550 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | Solubility in hot Methanol (almost transparency). |
| pka | 10.83±0.20(Predicted) |
| form | Crystalline Powder |
| color | Light beige to tan |
| PH | 2.95 at 24.7℃ and 10g/L |
| BRN | 1237255 |
| InChI | 1S/C6H8O2/c1-4-5(7)2-3-6(4)8/h4H,2-3H2,1H3 |
| InChIKey | HXZILEQYFQYQCE-UHFFFAOYSA-N |
| SMILES | CC1C(=O)CCC1=O |
| LogP | -0.8 at 30℃ and pH7.66 |
| CAS DataBase Reference | 765-69-5(CAS DataBase Reference) |
| FDA UNII | C9LG5VP01C |
| NIST Chemistry Reference | 1,3-Cyclopentanedione, 2-methyl-(765-69-5) |
| UNSPSC Code | 12352115 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29142900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
2-Methyl-1,3-cyclopentanedione price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 117021 | 2-Methyl-1,3-cyclopentanedione 99% | 765-69-5 | 5g | $28.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 117021 | 2-Methyl-1,3-cyclopentanedione 99% | 765-69-5 | 25g | $61.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.10504 | 2-Methyl-1,3-cyclopentanedione for synthesis | 765-69-5 | 10g | $64.1 | 2022-05-15 | Buy |
| TCI Chemical | M0901 | 2-Methyl-1,3-cyclopentanedione >97.0%(GC)(T) | 765-69-5 | 5g | $35 | 2026-04-30 | Buy |
| TCI Chemical | M0901 | 2-Methyl-1,3-cyclopentanedione >97.0%(GC)(T) | 765-69-5 | 25g | $95 | 2026-04-30 | Buy |
2-Methyl-1,3-cyclopentanedione Chemical Properties,Uses,Production
Chemical Properties
LIGHT BEIGE TO TAN CRYSTALLINE POWDER
Uses
2-Methyl-1,3-cyclopentanedione was used as a reactant in the identification and characterization of benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.
Uses
2-Methyl-1,3-cyclopentanedione hs been used to explore deoxycholic acid (DCA) induced changes in cell signaling. DCA is a secondary bile acid implicated in numerous pathological conditions. It has also been used in the synthesis of (-)-curcumanolide A and (-)-curcumalactone by aldol-lactonization.
Synthesis Reference(s)
Synthetic Communications, 19, p. 373, 1989 DOI: 10.1080/00397918908050676
Synthesis
614-45-9
3859-41-4
765-69-5
The general procedure for the synthesis of 2-methyl-1,3-cyclopentanedione from 1,3-cyclopentanedione and tert-butyl peroxybenzoate was as follows: 1,3-cyclopentanedione (0.098 g, 1 mmol), tert-butyl peroxybenzoate (0.58 g, 3 mmol), CuCl (0.01 g, 0.1 mmol), and 2 mL of acetic acid were added to a reaction flask, and the reaction was carried out at 120 °C Reaction at 120°C. The progress of the reaction was monitored by thin layer chromatography (TLC) until the reaction was complete. After completion of the reaction, the crude product was purified by column chromatography (eluent ratio of petroleum ether:ethyl acetate = 40:1) to afford the target product 2-methyl-1,3-cyclopentanedione in 68% yield.
References
[1] Patent: CN105254483, 2016, A. Location in patent: Paragraph 0044
2-Methyl-1,3-cyclopentanedione Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8736 | 58 |
View Lastest Price from 2-Methyl-1,3-cyclopentanedione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-26 | 2-Methyl-1, 3-Cyclopentanedione
765-69-5
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2025-04-04 | 2-Methyl-1,3-cyclopentanedione
765-69-5
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2024-04-27 | 2-Methylcyclopentane-1,3-dione
765-69-5
|
US $10.00 / kg | 1kg | 99.6% | 100000 | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- 2-Methyl-1, 3-Cyclopentanedione
765-69-5
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 2-Methyl-1,3-cyclopentanedione
765-69-5
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Methylcyclopentane-1,3-dione
765-69-5
- US $10.00 / kg
- 99.6%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
