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GB4

GB4 Structure
GB4 structure
CAS No.
11034-93-8
Chemical Name:
GB4
Synonyms
GLOBOSIDE;Tetrahexosylceramide (d18:1/12:0);Tetrahexosylceramide (d18:1/16:0);Tetrahexosylceramide (d18:1/18:0);Tetrahexosylceramide (d18:1/20:0);Tetrahexosylceramide (d18:1/22:0);Tetrahexosylceramide (d18:1/24:0);Tetrahexosylceramide (d18:1/25:0);Tetrahexosylceramide (d18:1/26:0);Tetrahexosylceramide (d18:1/9Z-18:1)
CBNumber:
CB5283013
Molecular Formula:
C56H102N2O23
Molecular Weight:
0
MDL Number:
MFCD00131163
MOL File:
11034-93-8.mol
MSDS File:
SDS
Last updated:2026-05-11 16:31:51
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GB4 Properties

storage temp. −20°C
solubility Chloroform:Methanol (2:1): Soluble; DMSO: Soluble; Methanol: Warmed
form A solid

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  29400090

GB4 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24881 Globotetraosylceramide (porcine RBC) ≥98% 11034-93-8 5mg $636 2026-04-30 Buy
Biosynth OG06812 Globoside 11034-93-8 1mg $277.55 2026-06-04 Buy
Biosynth OG06812 Globoside 11034-93-8 2mg $462.58 2026-06-04 Buy
Biosynth OG06812 Globoside 11034-93-8 5mg $848.15 2026-06-04 Buy
Biosynth OG06812 Globoside 11034-93-8 10mg $1580.6 2026-06-04 Buy
Product number Packaging Price Buy
24881 5mg $636 Buy
OG06812 1mg $277.55 Buy
OG06812 2mg $462.58 Buy
OG06812 5mg $848.15 Buy
OG06812 10mg $1580.6 Buy

GB4 Chemical Properties, Uses, Production

Description

Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, and parvovirus B19. Globotetraosylceramides increase the expression of proteins responsible for enamel deposition, including ameloblastin, amelogenin, and enamelin, in dental epithelial cells and activate the ERK and p38 MAPK signaling pathways. Levels of globotetraosylceramides are elevated in fibroblasts from patients with salt and pepper syndrome, a neurocutaneous condition characterized by intellectual disability and hyper- and hypo-pigmented skin. Globotetraosylceramides (porcine RBC) contains a mixture of globotetraosylceramides with variable fatty acyl chain lengths isolated from porcine red blood cells. [Matreya, LLC. Catalog No. 1068]

Chemical Properties

White powder

Uses

Globotetraosylceramide (porcine RBC) is a biochemical reagent.

References

[1] T YAMAKAWA  N K  S YOKOYAMA. Structure of main globoside of human erythrocytes.[J]. Journal of biochemistry, 1962, 52: 228-229. DOI: 10.1093/oxfordjournals.jbchem.a127603
[2] J. MüTHING. Shiga toxins, glycosphingolipid diversity, and endothelial cell injury[J]. Thrombosis and haemostasis, 2009, 101 1: 252-264. DOI: 10.1160/th08-05-0317
[3] YUKO MATSUSHIMA-HIBIYA. Identification of glycosphingolipid receptors for pierisin-1, a guanine-specific ADP-ribosylating toxin from the cabbage butterfly.[J]. The Journal of Biological Chemistry, 2003, 278 11: 9972-9978. DOI: 10.1074/jbc.m212114200
[4] WAQAS NASIR . Parvovirus B19 VLP recognizes globoside in supported lipid bilayers[J]. Virology, 2014, 456: Pages 364-369. DOI: 10.1016/j.virol.2014.04.004
[5] TAKASHI NAKAMURA. Globoside accelerates the differentiation of dental epithelial cells into ameloblasts[J]. International Journal of Oral Science, 2016, 8 4: 205-212. DOI: 10.1038/ijos.2016.35
[6] LUIGI BOCCUTO. A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation.[J]. Human molecular genetics, 2014, 23 2: 418-433. DOI: 10.1093/hmg/ddt434

GB4 Preparation Products And Raw materials

Raw materials

Preparation Products

GB4 Suppliers

Global Suppliers ( 36)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1978 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9170 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shandong Xiya Chemical Co., Ltd. 4009903999 13395398332 sales@xiyashiji.com China 20788 60
Shandong Ono Chemical Co., Ltd. 0539-6362799 20） China 9998 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
BOC Sciences 16314854226 inquiry@bocsci.com United States 9713 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Yichang Zhongyitai Trading Co., Ltd. 58
Alfa Chemistry 60
Shanghai EFE Biological Technology Co., Ltd. 58
Shandong Xiya Chemical Co., Ltd. 60
Shandong Ono Chemical Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
BOC Sciences 58

View Latest Price from GB4 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Globotetraosylceramides (porcine RBC) pictures 2026-05-11 Globotetraosylceramides (porcine RBC)
11034-93-8
 $1980.00 10g TargetMol Chemicals Inc.

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Ceramide,1-O-[O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1-)3)-O-α-D-galactopyranosyl-(1-)4)-O-β-D-galactopyranosyl-(1-)4)-β-D-glucopyranosyl]- CytolipinK GangliosideGL4 globosidefromhumanerythrocytes GlobosideGL4 GlobosideI Globosidicacid GBOSE4CER GB4 GL4 GLOBOSIDES GLOBOTETRAHEXOSYL-CERAMIDE GLOBOTETRAOSYLCERAMIDE GLOBOTETRAOSYL CREAMIDE N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)dodecanamide N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)hexadecanamide N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)octadecanamide N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)icosanamide N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)docosanamide N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)tetracosanamide (Z)-N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)tetracos-15-enamide N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)pentacosanamide N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)hexacosanamide (Z)-N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)hexacos-17-enamide (Z)-N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)octadec-9-enamide GLOBOTETRAOSYLCERAMIDE, FROM PORCINE ERYTHROCYTE (Z)-1-O-[4-O-[4-O-[3-O-(2-Deoxy-2-acetylamino-β-D-glucopyranosyl)-α-D-galactopyranosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyl]-N-(1-oxotetracosyl)-4-sphingenine Globosides (huMan) Globosylceramide N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide Globotetraosylceramides (porcine RBC) Globotetraosylceramide (porcine RBC) GLOBOSIDE Tetrahexosylceramide (d18:1/12:0) Tetrahexosylceramide (d18:1/16:0) Tetrahexosylceramide (d18:1/18:0) Tetrahexosylceramide (d18:1/20:0) Tetrahexosylceramide (d18:1/22:0) Tetrahexosylceramide (d18:1/24:0) Tetrahexosylceramide (d18:1/24:1(15Z)) Tetrahexosylceramide (d18:1/25:0) Tetrahexosylceramide (d18:1/26:0) Tetrahexosylceramide (d18:1/26:1(17Z)) Tetrahexosylceramide (d18:1/9Z-18:1) 11034-93-8 Biochemicals and Reagents BioChemical Glycolipids Complex Lipids Lipids Others