Serpin G1
- CAS No.
- Chemical Name:
- Serpin G1
- Synonyms
- HAE2;C1IN;C1nh;C1inh;Serpin G1;C1 INHIBITOR human;Plasma protease C1 inhibitor;Human SERPING1 Protein, His Tag;Recombinant Human SERPING1 Protein, His Tag;Recombinant Mouse Serping1 Protein, His Tag
- CBNumber:
- CB52923124
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Serpin G1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3318 | C1 Inhibitor human recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC) | 200 μg | $382 | 2026-04-30 | Buy | |
| Usbiological | 576039 | SERPING1 PurifiedbyProteinGaffinitychromatography. | 50ug | $509 | 2026-06-03 | Buy | |
| Usbiological | 576039 | SERPING1 PurifiedbyProteinGaffinitychromatography. | 100ug | $708 | 2026-06-03 | Buy | |
| Usbiological | 528153 | SERPING1 Purifiedbyimmunoaffinitychromatography. | 100ul | $736 | 2026-06-03 | Buy | |
| Usbiological | 528153 | SERPING1 Purifiedbyimmunoaffinitychromatography. | 200ul | $944 | 2026-06-03 | Buy |
Serpin G1 Chemical Properties, Uses, Production
Uses
Plasma protease C1 inhibitor is a member of the serpin family of structurally related proteins. Recombinant Human C1 inhibitor is a highly glycosylated glycoprotein containing 478 amino acid residues (52.8kDa), corresponding to amino acids 23-500 of the C1 inhibitor precursor, and is fully functional in its ability to inhibit the C1 complex. Glycosylated C1 inhibitor migrates at an apparent molecular weight of approximately 80-90kDa by SDS PAGE analysis under reducing conditions.
Biological Activity
Plasma protease C1 inhibitor is the primary regulator of the immune complement system. C1 inhibitor is a protease inhibitor th at functions to inhibit the complement system in order to prevent over-activation or spontaneous activation. Inhibition is achieved by binding to and irreversibly inhibiting the C1r and C1s proteases of the C1 complex, which has the effect of shutting down all subsequent downstream events in the complement activation cascade. C1 inhibitor can also inhibit various other proteases, including Kallikrein, Factor XIa, and Factor XIIa. Deficiencies in C1 inhibitor are the primary cause of hereditary angioedema (HAE, hereditary angioneurotic edema), a disease characterized by edema in the respiratory and gastrointestinal tracts. In certain clinical situations, the direct administration of C1 inhibitor can be used to tre at HAE and certain other conditions.
Serpin G1 Preparation Products And Raw materials
Raw materials
Preparation Products
Serpin G1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9926 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| ACROBiosystems | 13121935750 | jiaxin.zhao@acrobiosystems.com | China | 1592 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8165 | 58 |
| shlmai | 021-67680335 13052188602 | sale1@shlmai.net | China | 10000 | 58 |
| Supplier | Advantage |
|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 58 |
| Biolab Reagents | 58 |
| ACROBiosystems | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 58 |
| shlmai | 58 |
