trans-Cyclooctene-maleimide
- CAS No.
- 1609659-01-9
- Chemical Name:
- trans-Cyclooctene-maleimide
- Synonyms
- TCO-PEG3-maleimide;(4E)-TCO-PEG3-Maleimide;trans-Cyclooctene-maleimide;(4E)-TCO-C1-PEG3-C1-Maleimide;TCO-PEG3-Maleimide (CCT-1002);Trans-Cyclooctene-PEG3-Maleimide,TCO-PEG3-Maleimide;6,9,12-Trioxa-2,16-diazanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-, 4-cycloocten-1-yl ester
- CBNumber:
- CB52925335
- Molecular Formula:
- C26H41N3O8
- Molecular Weight:
- 523.62
- MDL Number:
- MFCD28053553
- MOL File:
- 1609659-01-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 717.1±60.0 °C(Predicted) |
|---|---|
| Density | 1.19±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| pka | 12.38±0.46(Predicted) |
| form | liquid |
| InChIKey | BJZRPWAVCDJCTC-OWOJBTEDSA-N |
| SMILES | O=C(NCCCOCCOCCOCCCNC(CCN1C(C=CC1=O)=O)=O)OC2CCC/C=C/CC2 |
| UNSPSC Code | 12352111 |
| NACRES | NA.22 |
trans-Cyclooctene-maleimide price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 790443 | TCO-PEG3-maleimide | 1609659-01-9 | 5mg | $305 | 2026-04-30 | Buy |
| Sigma-Aldrich | 790443 | TCO-PEG3-maleimide | 1609659-01-9 | 25mg | $752 | 2026-04-30 | Buy |
| Biosynth | JPC65901 | TCO-PEG3-maleimide | 1609659-01-9 | 50mg | $910.5 | 2026-06-04 | Buy |
| Biosynth | JPC65901 | TCO-PEG3-maleimide | 1609659-01-9 | 100mg | $1458 | 2026-06-04 | Buy |
| dPEG | CCT-1002-25 | TCO-PEG3-Maleimide | 25mg | $270 | 2026-06-04 | Buy |
trans-Cyclooctene-maleimide Chemical Properties, Uses, Production
reaction suitability
reaction type: click chemistry
reagent type: linker
Biochem/physiol Actions
Maleimide (thiol reactive) functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into thiol containing compounds or biomolecules. Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging. The PEG spacer allows for increased water solubility; less aggregation and an increased distance between the thiol to be modified and the reactive alkene.
trans-Cyclooctene-maleimide Preparation Products And Raw materials
Raw materials
Preparation Products
trans-Cyclooctene-maleimide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Changzhou Hopschain Chemical Co.,Ltd. | 85528066 13775048983 | sales@hopschem.com | China | 31548 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Zhengzhou Acme Chemical Co., Ltd. | 037163312495 13303845143 | 1416159398@qq.com | China | 10151 | 58 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1644 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1977 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39866 | 58 |
| Changsha Bono New Materials Technology Co., Ltd. | 18191076804 | asherw9@hotmail.com | China | 2373 | 58 |
| Hangzhou Taorui Biotechnology Co., Ltd | QQ1259737804 15268198094 | sales@torreybio.com | China | 4129 | 58 |
View Latest Price from trans-Cyclooctene-maleimide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | (4E)-TCO-PEG3-Maleimide
1609659-01-9
|
5mg | >95.00% | 5mg | Xian confluore Biological Technology Co., Ltd. |
-
- (4E)-TCO-PEG3-Maleimide
1609659-01-9
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
