3-CHLORO-4-METHYLBENZONITRILE
- CAS No.
- 21423-81-4
- Chemical Name:
- 3-CHLORO-4-METHYLBENZONITRILE
- Synonyms
- 3-CHLORO-4-TOLUNITRILE;3-CHLORO-P-TOLUNITRILE;3-chloro-p-toluonitrile;2-Chloro-4-cyanotoluene;3-Chlor-4-methyl-benzonitril;3-CHLORO-4-METHYLBENZONITRILE;3-Chloro-4-methylaminobenzoate;Benzonitrile, 3-chloro-4-methyl-;3-Chloro-4-methylbenzonitrile 98%;3-Chloro-4-Methylbenzonitrile, 97%+
- CBNumber:
- CB5293733
- Molecular Formula:
- C8H6ClN
- Molecular Weight:
- 151.59
- MDL Number:
- MFCD00001799
- MOL File:
- 21423-81-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Chloro-4-methylbenzonitrile 97% | 149705 | 5g | $119 |
| 3-Chloro-4-methylbenzonitrile min. 98.0 % | C3104 | 5G | $95 |
| 3-Chloro-4-methylbenzonitrile min. 98.0 % | C3104 | 25G | $287 |
| 3-Chloro-4-methylbenzonitrile | C602265 | 250mg | $45 |
| 3-Chloro-4-methylbenzonitrile 98% | OR3687 | 5g | $54 |
| More product size | |||
| Melting point | 45-48 °C (lit.) |
|---|---|
| Boiling point | 106°C/6mm |
| Density | 1.19 |
| Flash point | 183 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| color | White to Light yellow |
| InChI | InChI=1S/C8H6ClN/c1-6-2-3-7(5-10)4-8(6)9/h2-4H,1H3 |
| InChIKey | INEMHABDFCKBID-UHFFFAOYSA-N |
| SMILES | C(#N)C1=CC=C(C)C(Cl)=C1 |
| CAS DataBase Reference | 21423-81-4(CAS DataBase Reference) |
| FDA UNII | 9NV76ZQA7A |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H228-H301-H311-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P310a-P305+P351+P338-P405-P501a-P210 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi,F | |||||||||
| Risk Statements | 11 | |||||||||
| Safety Statements | 36 | |||||||||
| RIDADR | UN 1325 4.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2926907090 | |||||||||
| Storage Class | 4.1B - Flammable solid hazardous materials | |||||||||
| Hazard Classifications | Flam. Sol. 2 | |||||||||
| NFPA 704 |
|
3-CHLORO-4-METHYLBENZONITRILE price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 149705 | 3-Chloro-4-methylbenzonitrile 97% | 21423-81-4 | 5g | $119 | 2023-01-07 | Buy |
| TCI Chemical | C3104 | 3-Chloro-4-methylbenzonitrile min. 98.0 % | 21423-81-4 | 5G | $95 | 2025-07-31 | Buy |
| TCI Chemical | C3104 | 3-Chloro-4-methylbenzonitrile min. 98.0 % | 21423-81-4 | 25G | $287 | 2025-07-31 | Buy |
| TRC | C602265 | 3-Chloro-4-methylbenzonitrile | 21423-81-4 | 250mg | $45 | 2021-12-16 | Buy |
| Apolloscientific | OR3687 | 3-Chloro-4-methylbenzonitrile 98% | 21423-81-4 | 5g | $54 | 2021-12-16 | Buy |
3-CHLORO-4-METHYLBENZONITRILE Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
3-Chloro-4-methylbenzonitrile may be used in chemical synthesis studies.
Synthesis
863431-87-2
21423-81-4
In a 1L four-neck flask, 161.4 g of dimethyl 2-(4-cyano-2-chlorophenyl)-1,3-malonate (1 eq.), 21.7 g of water (2 eq.), and 140.9 g of 95% anhydrous calcium chloride (2 eq.) were added to 606 g of N,N-dimethylacetamide. The reaction was stirred and heated to 140-145°C and kept at this temperature for 20-24 hours. After completion of the reaction, cooled to 30 °C, 352.5 g of water and 303 g of dichloromethane were added. About 70.2 g of concentrated hydrochloric acid was added slowly and the pH of the system was adjusted to 5-7. After partitioning, the aqueous layer was extracted with dichloromethane and the organic phases were combined. The organic phase was concentrated under reduced pressure to give a solution of N,N-dimethylacetamide containing 3-chloro-4-methylbenzonitrile. Vacuum distillation was continued to collect 3-chloro-4-methylbenzonitrile until no product evaporated, resulting in 75.9 g of white solid in 83.0% yield.
References
[1] Patent: CN107673994, 2018, A. Location in patent: Paragraph 0135; 0136; 0137
3-CHLORO-4-METHYLBENZONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30228 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14343 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52722 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
View Lastest Price from 3-CHLORO-4-METHYLBENZONITRILE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-01-15 | 3-Chlor-4-methyl-benzonitril
21423-81-4
|
US $0.00 / KG | 1KG | 98.1% | 100 tons | Honest Joy Holdings Limited |
-
- 3-Chlor-4-methyl-benzonitril
21423-81-4
- US $0.00 / KG
- 98.1%
- Honest Joy Holdings Limited
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