1-Methyl-1H-indole-5-carbaldehyde
- CAS No.
- 90923-75-4
- Chemical Name:
- 1-Methyl-1H-indole-5-carbaldehyde
- Synonyms
- 1-Methylindolecarbaldehyde;5-Formyl-1-methyl-1H-indole;1-Methylindole-5-carbaldehyde;1-Methylindole-5-carboxaldehyde;1-Methyl-1H-indole-5-carbaldehyde;1-METHYL-1H-INDOLE-5-CARBOXALDEHYDE;1H-Indole-5-carboxaldehyde, 1-methyl-;1-Methyl-1H-indole-5-carboxaldehyde97%;1-Methyl-1H-indole-5-carboxaldehyde 97%;1-Methyl-1H-indole-5-carboxaldehyde
- CBNumber:
- CB5294013
- Molecular Formula:
- C10H9NO
- Molecular Weight:
- 159.18
- MDL Number:
- MFCD08271908
- MOL File:
- 90923-75-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 84-85.5 |
|---|---|
| Boiling point | 318.7±15.0 °C(Predicted) |
| Density | 1.10±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Solid |
| Appearance | Off-white to light yellow Solid |
| Sensitive | Air & Moisture Sensitive |
| InChI | InChI=1S/C10H9NO/c1-11-5-4-9-6-8(7-12)2-3-10(9)11/h2-7H,1H3 |
| InChIKey | XIVDZBIBWGQOTI-UHFFFAOYSA-N |
| SMILES | N1(C)C2=C(C=C(C=O)C=C2)C=C1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Harmful | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933998090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
1-Methyl-1H-indole-5-carbaldehyde price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 774561 | 1-Methyl-1H-indole-5-carboxaldehyde 97% | 90923-75-4 | 500mg | $214 | 2026-04-30 | Buy |
| Apolloscientific | OR9157 | 1-Methyl-1H-indole-5-carboxaldehyde 97% | 90923-75-4 | 250mg | $36 | 2026-06-04 | Buy |
| Apolloscientific | OR9157 | 1-Methyl-1H-indole-5-carboxaldehyde 97% | 90923-75-4 | 1g | $69 | 2026-06-04 | Buy |
| Apolloscientific | OR9157 | 1-Methyl-1H-indole-5-carboxaldehyde 97% | 90923-75-4 | 5g | $249 | 2026-06-04 | Buy |
| Activate Scientific | AS140250 | 1-Methyl-1H-indole-5-carbaldehyde 97% | 90923-75-4 | 1g | $84 | 2026-06-04 | Buy |
1-Methyl-1H-indole-5-carbaldehyde Chemical Properties, Uses, Production
Synthesis
1196-69-6
74-88-4
90923-75-4
To a solution of 5-indolecarboxaldehyde (1.0 g, 6.9 mmol) in N,N-dimethylformamide (DMF, 15 mL) was added sodium hydride (303 mg, 60% oil dispersion, 7.59 mmol) in one portion. The reaction mixture was stirred at room temperature for 30 minutes. Subsequently, iodomethane (1.96 g, 13.8 mmol) was added to the reaction system and the mixture was continued to stir overnight. Upon completion of the reaction, ethyl acetate (200 mL) was added to dilute the reaction mixture, and the organic phase was washed sequentially with water (3 x 20 mL) and saturated saline (25 mL). The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated to afford 1-methyl-1H-indole-5-carbaldehyde as an orange oil (1.0 g, 91% yield). The product was characterized by 1H NMR (200 MHz, CDCl3): δ 10.05 (s, 1H), 8.09 (s, 1H), 7.90-7.80 (m, 1H), 7.35-7.15 (m, 2H), 6.85-6.80 (m, 1H), 3.95 (s, 3H).
References
[1] Patent: WO2004/52890, 2004, A1. Location in patent: Page 91-92
[2] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 7, p. 2060 - 2079
[3] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 167 - 183
[4] Patent: US2005/209274, 2005, A1. Location in patent: Page/Page column 27
[5] Journal of Organometallic Chemistry, 2011, vol. 696, # 5, p. 1072 - 1083
1-Methyl-1H-indole-5-carbaldehyde Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1-Methyl-1H-indole-5-carbaldehyde Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Sealing Biotechnology Co. Ltd.. | 15721176654;15710104046 | 1815535157@qq.com | China | 984 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| skychemical Co.Ltd | 021-20958197 20965099 | sales@skychemical.com | China | 1182 | 57 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. | 02161555100 | China | 820 | 58 | |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| skychemical Co.Ltd | 021-20960837,QQ1332204249 | sales@skychemical.com | China | 3338 | 55 |
View Latest Price from 1-Methyl-1H-indole-5-carbaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-12-20 | 1-METHYL-1H-INDOLE-5-CARBALDEHYDE
90923-75-4
|
1g | 95%min | 20kg/month | Nanjing jinheyou Trading Co., Ltd. |
-
- 1-METHYL-1H-INDOLE-5-CARBALDEHYDE
90923-75-4
- $0.00
- 95%min
- Nanjing jinheyou Trading Co., Ltd.
