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2-Fluorophenylacetic acid

CAS No.
451-82-1
Chemical Name:
2-Fluorophenylacetic acid
Synonyms
O-fluorine acid;RARECHEM AL BO 0110;2-Fluorophenylacetic;o-flurophenylacetic acid;2-Fluorphenylessigsaeure;2-fluoro-benzeneaceticaci;2-FLUOROPHENYLACETIC ACID;O-FLUOROPHENYLACETIC ACID;2-fluoro-benzeneacetic acid;2-Fluorophenylaceticacid97%
CBNumber:
CB5297100
Molecular Formula:
C8H7FO2
Molecular Weight:
154.14
MDL Number:
MFCD00004315
MOL File:
451-82-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:31:39
Product description Number Pack Size Price
2-Fluorophenylacetic acid 98% 208949 10g $103
2-Fluorophenylacetic Acid >98.0%(GC)(T) F0205 5g $27
2-Fluorophenylacetic Acid >98.0%(GC)(T) F0205 25g $70
2-Fluorobenzeneacetic Acid TRC-F588310-50G 50g $154
2-Fluorobenzeneacetic Acid TRC-F588310-250G 250g $347
More product size

2-Fluorophenylacetic acid Properties

Melting point 60-62 °C (lit.)
Boiling point 203.5°C (rough estimate)
Density 1.1850 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
pka 4.01±0.10(Predicted)
color Off-White
BRN 775955
InChI InChI=1S/C8H7FO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11)
InChIKey RPTRFSADOICSSK-UHFFFAOYSA-N
SMILES C1(CC(O)=O)=CC=CC=C1F
CAS DataBase Reference 451-82-1(CAS DataBase Reference)
FDA UNII X2W3C5ER3N
NIST Chemistry Reference O-fluorophenylacetic acid(451-82-1)
EPA Substance Registry System Benzeneacetic acid, 2-fluoro- (451-82-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335
Precautionary statements  P280g-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  38-36/37/38
Safety Statements  22-24/25-36/37/39-27-26
WGK Germany  3
13
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29163990
Storage Class 11 - Combustible Solids
Hazard Classifications Skin Irrit. 2
NFPA 704
0
0 0

2-Fluorophenylacetic acid price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 208949 2-Fluorophenylacetic acid 98% 451-82-1 10g $103 2023-06-20 Buy
TCI Chemical F0205 2-Fluorophenylacetic Acid >98.0%(GC)(T) 451-82-1 5g $27 2026-04-30 Buy
TCI Chemical F0205 2-Fluorophenylacetic Acid >98.0%(GC)(T) 451-82-1 25g $70 2026-04-30 Buy
TRC TRC-F588310-50G 2-Fluorobenzeneacetic Acid 451-82-1 50g $154 2026-06-03 Buy
TRC TRC-F588310-250G 2-Fluorobenzeneacetic Acid 451-82-1 250g $347 2026-06-03 Buy
Product number Packaging Price Buy
208949 10g $103 Buy
F0205 5g $27 Buy
F0205 25g $70 Buy
TRC-F588310-50G 50g $154 Buy
TRC-F588310-250G 250g $347 Buy

2-Fluorophenylacetic acid Chemical Properties,Uses,Production

Chemical Properties

white to off-white shiny crystals or crystalline

Uses

2-Fluorophenylacetic acid was used:

  • in the synthesis of thiazolino[3,2-c]pyrimidin-5,7-diones and N-[2-(3,4-dichlorophenyl)-ethyl]-N′-[2-(2-fluorophenyl)-ethyl]-ethane-1,2-diamine
  • as chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy

General Description

2-Fluorophenylacetic acid is chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy.

Synthesis

The Schlenk tube was heated under a high vacuum, pre-dried with calcium chloride, and filled with CO2 gas. Bis(4-methoxyphenyl)zinc magnesium chloride lithium chloride (12.8 ml, 0:39 M in THF, 5.0 mmol) was added, and CO2 was passed through the solution for 5 minutes. The reaction mixture was stirred at 25 °C for 6 hours. Diethyl ether (50 ml) was added, and the organic phase was extracted with 2M NaOH (3×50 ml). The combined aqueous phases were acidified with 2M HCl (pH <5) and extracted with diethyl ether (3×50 ml). The combined organic phases were dried over sodium sulfate, and the solvent was removed in vacuo. 2-Fluorophenylacetic acid was obtained in a yield of 100%.

Global( 440)Suppliers
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Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Chuanghai Biotechnology Co,.LTD
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Capot Chemical Co.,Ltd.
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8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd
027-67849912 sales@chemwish.com CHINA 10821 58

View Lastest Price from 2-Fluorophenylacetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Fluorophenylacetic acid pictures 2026-06-05 2-Fluorophenylacetic acid
451-82-1
$170.00 1KG 98% 200tons/ year Speranza Chemical Co., Ltd.
2-Fluorophenylacetic acid pictures 2026-05-28 2-Fluorophenylacetic acid
451-82-1
$9.00 1KG 99.9 1 ton Hebei Chuanghai Biotechnology Co,.LTD
2-Fluorophenylacetic acid pictures 2026-03-20 2-Fluorophenylacetic acid
451-82-1
$10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
RARECHEM AL BO 0110 O-FLUOROPHENYLACETIC ACID 2-FLUOROPHENYLACETIC ACID 2-fluoro-benzeneaceticaci Acetic acid, (o-fluorophenyl)- Benzeneacetic acid, 2-fluoro- o-Fluorophenylacetic Acid 2-Fluorophenylacetic Acid 2-Fluorophenylacetic acid, 98+% 2-Fluorophenylacetic acid 97% 2-Fluorophenylaceticacid97% 2-fluoro-benzeneacetic acid 2-Fluorophenylacetic O-fluorine acid o-flurophenylacetic acid 2-Fluorophenylacetic acid, 98% 10GR Orthofluorophenyl acetic acid Adjacent fluorine benzene acetic acid o-2-Fluorophenylacetic Acid 2-Fluorphenylessigsaeure 2-Fluorophenylacetic acid ISO 9001:2015 REACH 451-82-1 FA - FL Organic Building Blocks C8 Carbonyl Compounds Carboxylic Acids Building Blocks Analytical Standards Alphabetic Analytical Chromatography Product Catalog Aryl Fluorinated Building Blocks Building Blocks C7-C8 Carbonyl Compounds Carboxylic Acids Chemical Synthesis Fluorinated Building Blocks Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks Imidazoles Aromatic Phenylacetic Acids and Derivatives Fluorobenzene Phenylacetic acid C8 Carbonyl Compounds Carboxylic Acids Alphabetic F FA - FL Phenylacetic acid series