2-Fluorophenylacetic acid
- CAS No.
- 451-82-1
- Chemical Name:
- 2-Fluorophenylacetic acid
- Synonyms
- O-fluorine acid;RARECHEM AL BO 0110;2-Fluorophenylacetic;o-flurophenylacetic acid;2-Fluorphenylessigsaeure;2-fluoro-benzeneaceticaci;2-FLUOROPHENYLACETIC ACID;O-FLUOROPHENYLACETIC ACID;2-fluoro-benzeneacetic acid;2-Fluorophenylaceticacid97%
- CBNumber:
- CB5297100
- Molecular Formula:
- C8H7FO2
- Molecular Weight:
- 154.14
- MDL Number:
- MFCD00004315
- MOL File:
- 451-82-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Fluorophenylacetic acid 98% | 208949 | 10g | $103 |
| 2-Fluorophenylacetic Acid >98.0%(GC)(T) | F0205 | 5g | $27 |
| 2-Fluorophenylacetic Acid >98.0%(GC)(T) | F0205 | 25g | $70 |
| 2-Fluorobenzeneacetic Acid | TRC-F588310-50G | 50g | $154 |
| 2-Fluorobenzeneacetic Acid | TRC-F588310-250G | 250g | $347 |
| More product size | |||
| Melting point | 60-62 °C (lit.) |
|---|---|
| Boiling point | 203.5°C (rough estimate) |
| Density | 1.1850 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 4.01±0.10(Predicted) |
| color | Off-White |
| BRN | 775955 |
| InChI | InChI=1S/C8H7FO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11) |
| InChIKey | RPTRFSADOICSSK-UHFFFAOYSA-N |
| SMILES | C1(CC(O)=O)=CC=CC=C1F |
| CAS DataBase Reference | 451-82-1(CAS DataBase Reference) |
| FDA UNII | X2W3C5ER3N |
| NIST Chemistry Reference | O-fluorophenylacetic acid(451-82-1) |
| EPA Substance Registry System | Benzeneacetic acid, 2-fluoro- (451-82-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H315-H335 | |||||||||
| Precautionary statements | P280g-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 38-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36/37/39-27-26 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 13 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Skin Irrit. 2 | |||||||||
| NFPA 704 |
|
2-Fluorophenylacetic acid price More Price(72)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 208949 | 2-Fluorophenylacetic acid 98% | 451-82-1 | 10g | $103 | 2023-06-20 | Buy |
| TCI Chemical | F0205 | 2-Fluorophenylacetic Acid >98.0%(GC)(T) | 451-82-1 | 5g | $27 | 2026-04-30 | Buy |
| TCI Chemical | F0205 | 2-Fluorophenylacetic Acid >98.0%(GC)(T) | 451-82-1 | 25g | $70 | 2026-04-30 | Buy |
| TRC | TRC-F588310-50G | 2-Fluorobenzeneacetic Acid | 451-82-1 | 50g | $154 | 2026-06-03 | Buy |
| TRC | TRC-F588310-250G | 2-Fluorobenzeneacetic Acid | 451-82-1 | 250g | $347 | 2026-06-03 | Buy |
2-Fluorophenylacetic acid Chemical Properties,Uses,Production
Chemical Properties
white to off-white shiny crystals or crystalline
Uses
2-Fluorophenylacetic acid was used:
- in the synthesis of thiazolino[3,2-c]pyrimidin-5,7-diones and N-[2-(3,4-dichlorophenyl)-ethyl]-N′-[2-(2-fluorophenyl)-ethyl]-ethane-1,2-diamine
- as chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy
General Description
2-Fluorophenylacetic acid is chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy.
Synthesis
The Schlenk tube was heated under a high vacuum, pre-dried with calcium chloride, and filled with CO2 gas. Bis(4-methoxyphenyl)zinc magnesium chloride lithium chloride (12.8 ml, 0:39 M in THF, 5.0 mmol) was added, and CO2 was passed through the solution for 5 minutes. The reaction mixture was stirred at 25 °C for 6 hours. Diethyl ether (50 ml) was added, and the organic phase was extracted with 2M NaOH (3×50 ml). The combined aqueous phases were acidified with 2M HCl (pH <5) and extracted with diethyl ether (3×50 ml). The combined organic phases were dried over sodium sulfate, and the solvent was removed in vacuo. 2-Fluorophenylacetic acid was obtained in a yield of 100%.
2-Fluorophenylacetic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 923 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 2-Fluorophenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-05 | 2-Fluorophenylacetic acid
451-82-1
|
$170.00 | 1KG | 98% | 200tons/ year | Speranza Chemical Co., Ltd. | |
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2026-05-28 | 2-Fluorophenylacetic acid
451-82-1
|
$9.00 | 1KG | 99.9 | 1 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
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2026-03-20 | 2-Fluorophenylacetic acid
451-82-1
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-

- 2-Fluorophenylacetic acid
451-82-1
- $170.00
- 98%
- Speranza Chemical Co., Ltd.
-

- 2-Fluorophenylacetic acid
451-82-1
- $9.00
- 99.9
- Hebei Chuanghai Biotechnology Co,.LTD
-

- 2-Fluorophenylacetic acid
451-82-1
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd





