Ethyl sarcosinate hydrochloride
- CAS No.
- 52605-49-9
- Chemical Name:
- Ethyl sarcosinate hydrochloride
- Synonyms
- SARCOSINE ETHYL ESTER HYDROCHLORIDE;H-SAR-OET·HCL;Ethyl sarcosinate HCL;ethyl methylglycinate hydrochloride;ethyl N-methylaminoacetate hydrochloride;ethyl 2-(methylamino)acetate hydrochloride;SAR-OET HCL;H-SAR-OE HCL;L-Sar-OEt·HCl;H-SAR-OET HCL
- CBNumber:
- CB5305289
- Molecular Formula:
- C5H12ClNO2
- Molecular Weight:
- 153.61
- MDL Number:
- MFCD00012506
- MOL File:
- 52605-49-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Sarcosine ethyl ester hydrochloride 99% | 255084 | 10g | $84.9 |
| Sarcosine ethyl ester hydrochloride 99% | 255084 | 50g | $267 |
| Sarcosine Ethyl Ester Hydrochloride >98.0%(N)(T) | S0841 | 5g | $26 |
| Sarcosine Ethyl Ester Hydrochloride >98.0%(N)(T) | S0841 | 25g | $73 |
| Sarcosine Ethyl Ester Hydrochloride | 465869 | 1g | $319 |
| More product size | |||
| Melting point | ~125 °C |
|---|---|
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | H2O: 0.1 g/mL, clear |
| form | Crystalline Powder |
| color | White to off-white |
| Water Solubility | Soluble in water 0.1 g/mL. |
| Sensitive | Hygroscopic |
| BRN | 3911182 |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C5H11NO2.ClH/c1-3-8-5(7)4-6-2;/h6H,3-4H2,1-2H3;1H |
| InChIKey | NIDZUMSLERGAON-UHFFFAOYSA-N |
| SMILES | C(=O)(OCC)CNC.Cl |
| CAS DataBase Reference | 52605-49-9(CAS DataBase Reference) |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H319-H315 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29299090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Ethyl sarcosinate hydrochloride price More Price(89)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 255084 | Sarcosine ethyl ester hydrochloride 99% | 52605-49-9 | 10g | $84.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 255084 | Sarcosine ethyl ester hydrochloride 99% | 52605-49-9 | 50g | $267 | 2023-06-20 | Buy |
| TCI Chemical | S0841 | Sarcosine Ethyl Ester Hydrochloride >98.0%(N)(T) | 52605-49-9 | 5g | $26 | 2026-04-30 | Buy |
| TCI Chemical | S0841 | Sarcosine Ethyl Ester Hydrochloride >98.0%(N)(T) | 52605-49-9 | 25g | $73 | 2026-04-30 | Buy |
| Usbiological | 465869 | Sarcosine Ethyl Ester Hydrochloride | 52605-49-9 | 1g | $319 | 2026-06-03 | Buy |
Ethyl sarcosinate hydrochloride Chemical Properties,Uses,Production
Chemical Properties
white to off-white crystalline solid
Uses
Sarcosine ethyl ester hydrochloride is a metabolite of Sarcosine (S140500), which as been found in starfish and sea urchins. It is used as intermediate in the synthesis of antienzyme agents for toothpaste. Found to be a marker for prostate cancer bioagression.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
107-97-1
52605-49-9
Thiophenecarbonyl chloride (65 mL, 900 mmol) was added dropwise to a solution of sarcosine (20.0 g, 224 mmol) in ethanol (250 mL) cooled in an ice-water bath under stirring conditions, and the reaction temperature was maintained at about -10°C. After the dropwise addition was completed, the reaction mixture was gently heated at 55°C overnight until the solution became clear. Upon completion of the reaction, the solvent and residual thionyl chloride were removed by distillation under reduced pressure. The resulting solid residue was washed with ether (3 x 50 mL) and subsequently dried well under vacuum to afford ethyl sarcosinate hydrochloride (33.5 g, 218 mmol) in white powder form in 97% yield. The product could be used in subsequent steps without further purification. The product was characterized as follows: melting point 126°C (literature value 125-127°C); IR (ATR) ν cm1 2970-2440, 1742, 1229; 1H NMR (CDCl, 400 MHz) δ 9.64 (br.s, 2H, NH), 4.24 (q, 2H, 3J = 7.1 Hz, CHCH), 3.84 (t, 2H, 3J = 7.1 Hz, CHCH), 4.24 (q, 2H, 3J = 7.1 Hz, CH 3.84 (t, 2H, 3J = 5.7 Hz, NHCH), 2.80 (t, 3H, 3J = 5.2 Hz, NHCH), 1.26 (t, 3H, 3J = 7.1 Hz, CHCH); 13C NMR (CDCl, 101 MHz) δ 166.18 (CO), 62.62 (CHCH), 48.94 (NHCH), 33.34 (NHCH), 14.03 (CHCH).
References
[1] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 51 - 67
[2] Patent: US4432971, 1984, A
[3] Patent: US4432972, 1984, A
Ethyl sarcosinate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 17389186172 | 1077@dideu.com | China | 3999 | 58 |
| Sichuan HongRi Pharma-Tech Co.,Ltd | +86-15680023009 | ni@enlaibio.com | China | 1103 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1796 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1444 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 | sales@amoychem.com | China | 6339 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
View Lastest Price from Ethyl sarcosinate hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-13 | H-Sar-OEt.HCl
52605-49-9
|
1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2026-08-07 | Ethyl sarcosinate hydrochloride
52605-49-9
|
$1.00-4.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-06-30 | Ethyl sarcosinate hydrochloride
52605-49-9
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- H-Sar-OEt.HCl
52605-49-9
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- Ethyl sarcosinate hydrochloride
52605-49-9
- $1.00-4.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Ethyl sarcosinate hydrochloride
52605-49-9
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
