Elacestrant dihydrochloride
- CAS No.
- 1349723-93-8
- Chemical Name:
- Elacestrant dihydrochloride
- Synonyms
- Elacestrant HCl;Elacestrant 2HCl;Elacestrant DiHCl;RAD-1901;RAD1901 2HCl;RAD-1901 2HCl;RAD 1901 2HCl;RAD1901 HCl salt;RAD1901 dihydrochloride;Irastrant hydrochloride
- CBNumber:
- CB53145541
- Molecular Formula:
- C30H40Cl2N2O2
- Molecular Weight:
- 531.5568
- MDL Number:
- MFCD30532694
- MOL File:
- 1349723-93-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Elacestrant (hydrochloride) ≥98% | 37298 | 500μg | $40 |
| Elacestrant (hydrochloride) ≥98% | 37298 | 1mg | $76 |
| Elacestrant (hydrochloride) ≥98% | 37298 | 5mg | $335 |
| Elacestrant (hydrochloride) ≥98% | 37298 | 10mg | $590 |
| Elacestrant dihydrochloride | FE177759 | 1mg | $389.4 |
| solubility |
DMSO:100.0(Max Conc. mg/mL);188.13(Max Conc. mM) H2O:50.0(Max Conc. mg/mL);94.06(Max Conc. mM) |
|---|---|
| form | Solid |
| color | White to off-white |
| InChIKey | TVTRJGWMKDMZSN-AAZDGHFONA-N |
| SMILES | N(C1C=C(OC)C=CC=1[C@@H]1CCC2=CC(O)=CC=C2C1)(CC)CC1C=CC(CCNCC)=CC=1.Cl |&1:9,r| |
| FDA UNII | 8NZT0PR8AL |
Elacestrant dihydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 37298 | Elacestrant (hydrochloride) ≥98% | 1349723-93-8 | 500μg | $40 | 2026-04-30 | Buy |
| Cayman Chemical | 37298 | Elacestrant (hydrochloride) ≥98% | 1349723-93-8 | 1mg | $76 | 2026-04-30 | Buy |
| Cayman Chemical | 37298 | Elacestrant (hydrochloride) ≥98% | 1349723-93-8 | 5mg | $335 | 2026-04-30 | Buy |
| Cayman Chemical | 37298 | Elacestrant (hydrochloride) ≥98% | 1349723-93-8 | 10mg | $590 | 2026-04-30 | Buy |
| Biosynth | FE177759 | Elacestrant dihydrochloride | 1349723-93-8 | 1mg | $389.4 | 2026-06-04 | Buy |
Elacestrant dihydrochloride Chemical Properties,Uses,Production
Uses
Elacestrant (RAD1901) dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant dihydrochloride also can inhibit growth of ER+ breast cancer cell lines in vitro and in vivo[1][2].
in vivo
Elacestrant dihydrochloride (0.3-120 mg/kg; p.o.; single daily for 40 days) antagonizes E2-mediated uterine stimulation in a dose-dependent manner in vivo[1].
Elacestrant dihydrochloride (30, 60 mg/kg; p.o.; single daily for 4 weeks) induces complete tumor growth inhibition in mice[2].
Tumor growth inhibition is maintained for 4 weeks after Elacestrant dihydrochloride withdrawal[2].
| Animal Model: | MCF7 cell line xenograft model of mice[2]. |
| Dosage: | 30, 60 mg/kg |
| Administration: | Oral administration; single daily for 4 weeks. |
| Result: | Inhibited growth of tumor. |
References
[1] Garner F, et al. RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26(9):948-56. DOI:10.1097/CAD.0000000000000271
[2] Bihani T, et al. Elacestrant (RAD1901), a Selective Estrogen Receptor Degrader (SERD), Has Antitumor Activity in Multiple ER+ Breast Cancer Patient-derived Xenograft Models. Clin Cancer Res. 2017 Aug 15;23(16):4793-4804. DOI:10.1158/1078-0432.CCR-16-2561
Elacestrant dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Elacestrant dihydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Weiaokang Pharmaceutical Technology Co., Ltd | +undefined13424074264 | pengguizi@cti-cert.com | China | 156 | 58 |
| BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | +86-18600796368 | sales@sjar-tech.com | China | 529 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Changzhou Xuanming Pharmaceutical Technology Co., Ltd. | +86-519-85525359 +86-15995072465 | sales@xuanmingchem.com | China | 912 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28675 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
View Lastest Price from Elacestrant dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-12 | Elacestrant Dihydrochloride
956104-93-8
|
1g | More Than 99% | 100kg/Month | BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | ||
 |
2026-06-05 | Elacestrant dihydrochloride
1349723-93-8
|
$122.00-396.00 | 99.98% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-06-05 | Elacestrant dihydrochloride
1349723-93-8
|
$122.00-396.00 | 99.98% | 10g | TargetMol Chemicals Inc. |
-
- Elacestrant Dihydrochloride
956104-93-8
- $0.00
- More Than 99%
- BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
-
- Elacestrant dihydrochloride
1349723-93-8
- $122.00-396.00
- 99.98%
- TargetMol Chemicals Inc.
-
- Elacestrant dihydrochloride
1349723-93-8
- $122.00-396.00
- 99.98%
- TargetMol Chemicals Inc.
