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Eribulin intermediate

CAS No.
253128-15-3
Chemical Name:
Eribulin intermediate
Synonyms
Eribu;ER-076349;Eribulin N-3;Azerbrin Impurity 12;Eribulin Impurity 12;Eribulin Mesylate N-3;Eribulin mesylate Impurity 9;Eribulin intermediate,EribulinN-3;(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,35R...;Eribulin Impurity 12Q: What is Eribulin Impurity 12 Q: What is the CAS Number of Eribulin Impurity 12
CBNumber:
CB53339872
Molecular Formula:
C40H58O12
Molecular Weight:
730.88
MDL Number:
MFCD30532881
MOL File:
253128-15-3.mol
MSDS File:
SDS
Last updated:2025-05-08 20:29:14
Product description Number Pack Size Price
ER-076349 97% Y231865 5MG $1290
ER-076349 97% Y231865 10MG $2175
ER-076349 HY-42484 1mg $276
ER-076349 HY-42484 5mg $846
ER-076349 HY-42484 10mg $1425

Eribulin intermediate Properties

form Solid
color White to off-white
InChIKey NKVBBIDGGDRJNL-LUFZHUSSNA-N

Eribulin intermediate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ACHEMBLOCK Y231865 ER-076349 97% 253128-15-3 5MG $1290 2026-05-27 Buy
ACHEMBLOCK Y231865 ER-076349 97% 253128-15-3 10MG $2175 2026-05-27 Buy
Arctom HY-42484 ER-076349 253128-15-3 1mg $276 2026-05-26 Buy
Arctom HY-42484 ER-076349 253128-15-3 5mg $846 2026-05-26 Buy
Arctom HY-42484 ER-076349 253128-15-3 10mg $1425 2026-05-26 Buy
Product number Packaging Price Buy
Y231865 5MG $1290 Buy
Y231865 10MG $2175 Buy
HY-42484 1mg $276 Buy
HY-42484 5mg $846 Buy
HY-42484 10mg $1425 Buy

Eribulin intermediate Chemical Properties,Uses,Production

Uses

ER-076349 (Eribulin intermediate) is an inhibitor of tubulin polymerization, induces G2-M cell cycle arrest, and disrupts mitotic spindles. ER-076349 inhibits cancer cell growth, and inhibits tumor growth in several human tumor xenografts. ER-076349 is an analog of Halichondrin B[1].

References

[1] Towle MJ, et al. In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B. Cancer Res. 2001 Feb 1;61(3):1013-21. PMID:11221827

728043-99-0
253128-15-3
Synthesis of Eribulin intermediate from 7,11:10,14:13,16:21,24:27,31-Pentaepoxy-2H-cyclohentriaconta[b]furan-5,18(3H,4H)-dione, 2-[(2S)-2,3-dihydroxypropyl]octacosahydro-12,15-dihydroxy-3-methoxy-29-methyl-23,30-bis(methylene)-, (2R,3R,3aS,7R,10S,11R,12S,13S,14S,15S,16R,21S,24S,27S,29R,31R,32aS)- (9CI)

Eribulin intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

Eribulin intermediate Suppliers

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Eribulin N-3 Eribulin Impurity 12 11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one, 2-[(2S)-2,3-dihydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-, (2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)- ER-076349 (1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,35R... Eribulin Impurity 12Q: What is Eribulin Impurity 12 Q: What is the CAS Number of Eribulin Impurity 12 Eribulin Mesylate N-3 11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one,2-[(2S)-2,3-dihydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-,(2ChemicalbookR,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)- Eribu Eribulin mesylate Impurity 9 Azerbrin Impurity 12 11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one,2-[(2S)-2,3-dihydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-,(2R,3R,3aS,7R,8ChemicalbookaS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)- Eribulin intermediate,EribulinN-3 253128-15-3 C40H58O12