ChemicalBook >> CAS DataBase List >>Eribulin intermediate
Eribulin intermediate
- CAS No.
- 253128-15-3
- Chemical Name:
- Eribulin intermediate
- Synonyms
- Eribu;ER-076349;Eribulin N-3;Azerbrin Impurity 12;Eribulin Impurity 12;Eribulin Mesylate N-3;Eribulin mesylate Impurity 9;Eribulin intermediate,EribulinN-3;(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,35R...;Eribulin Impurity 12Q: What is Eribulin Impurity 12 Q: What is the CAS Number of Eribulin Impurity 12
- CBNumber:
- CB53339872
- Molecular Formula:
- C40H58O12
- Molecular Weight:
- 730.88
- MDL Number:
- MFCD30532881
- MOL File:
- 253128-15-3.mol
- MSDS File:
- SDS
Last updated:2025-05-08 20:29:14
| Product description | Number | Pack Size | Price |
| ER-076349 97% | Y231865 | 5MG | $1290 |
| ER-076349 97% | Y231865 | 10MG | $2175 |
| ER-076349 | HY-42484 | 1mg | $276 |
| ER-076349 | HY-42484 | 5mg | $846 |
| ER-076349 | HY-42484 | 10mg | $1425 |
Eribulin intermediate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ACHEMBLOCK | Y231865 | ER-076349 97% | 253128-15-3 | 5MG | $1290 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y231865 | ER-076349 97% | 253128-15-3 | 10MG | $2175 | 2026-05-27 | Buy |
| Arctom | HY-42484 | ER-076349 | 253128-15-3 | 1mg | $276 | 2026-05-26 | Buy |
| Arctom | HY-42484 | ER-076349 | 253128-15-3 | 5mg | $846 | 2026-05-26 | Buy |
| Arctom | HY-42484 | ER-076349 | 253128-15-3 | 10mg | $1425 | 2026-05-26 | Buy |
Eribulin intermediate Chemical Properties,Uses,Production
Uses
ER-076349 (Eribulin intermediate) is an inhibitor of tubulin polymerization, induces G2-M cell cycle arrest, and disrupts mitotic spindles. ER-076349 inhibits cancer cell growth, and inhibits tumor growth in several human tumor xenografts. ER-076349 is an analog of Halichondrin B[1].
References
[1] Towle MJ, et al. In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B. Cancer Res. 2001 Feb 1;61(3):1013-21. PMID:11221827


Synthesis of Eribulin intermediate from 7,11:10,14:13,16:21,24:27,31-Pentaepoxy-2H-cyclohentriaconta[b]furan-5,18(3H,4H)-dione, 2-[(2S)-2,3-dihydroxypropyl]octacosahydro-12,15-dihydroxy-3-methoxy-29-methyl-23,30-bis(methylene)-, (2R,3R,3aS,7R,10S,11R,12S,13S,14S,15S,16R,21S,24S,27S,29R,31R,32aS)- (9CI)
Eribulin intermediate Preparation Products And Raw materials
Eribulin intermediate Suppliers
Global( 32)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemExpress | +86-19370970350 +86-021-58950125 | info@chemexpress.com | China | 788 | 58 |
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| Xilinglab Co., Ltd. | +8618381337976 | bd@xilinglab.com | China | 86 | 58 |
| Shenzhen Nexcon Pharmatechs Ltd. | +86-0755-89396905 +86-18025329037 | admin@nexconn.com | China | 5209 | 58 |
| Henan Rane Chemical Co., Ltd. | +8618738066252 | info@ranechem.com | China | 2999 | 58 |
| WuYan Pharmaceutical Technology (Shanghai) Co., Ltd. | 18621565901 | sales@wuyanpharm.com | China | 136 | 55 |
| Xilinglab Co., Ltd. | 18884146872 | bd@xilinglab.com | China | 25 | 58 |
| Lianyungang TengFa Biological Technology Co. Ltd | 0518-85475186 18705131893 | wang666xt@163.com | China | 351 | 55 |
| Henan Anky Chemical Technology Co., Ltd. | 17836913271 | 3224305243@qq.com | China | 2850 | 58 |
| Jinan Yaoyan Pharmaceutical Co., Ltd. | jnyaoyan@163.com | China | 3069 | 58 |
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1of2
Eribulin N-3
Eribulin Impurity 12
11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one, 2-[(2S)-2,3-dihydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-, (2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-
ER-076349
(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,35R...
Eribulin Impurity 12Q: What is
Eribulin Impurity 12 Q: What is the CAS Number of
Eribulin Impurity 12
Eribulin Mesylate N-3
11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one,2-[(2S)-2,3-dihydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-,(2ChemicalbookR,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-
Eribu
Eribulin mesylate Impurity 9
Azerbrin Impurity 12
11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one,2-[(2S)-2,3-dihydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-,(2R,3R,3aS,7R,8ChemicalbookaS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-
Eribulin intermediate,EribulinN-3
253128-15-3
C40H58O12




