Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>4-(7-methoxyquinolin-4-yl)-2-methylphenol

4-(7-methoxyquinolin-4-yl)-2-methylphenol

4-(7-methoxyquinolin-4-yl)-2-methylphenol Structure
4-(7-methoxyquinolin-4-yl)-2-methylphenol structure
CAS No.
2165340-32-7
Chemical Name:
4-(7-methoxyquinolin-4-yl)-2-methylphenol
Synonyms
CU-CPT-9b;cas 2165340-32-7;CU-CPT-9B, CPD2004;CU-CPT9a >=98% (HPLC);CU-CPT-9a, 10 mM in DMSO;(7-methoxyquinolin-4-yl)-2-methylphenol;2-Methyl-4-(7-methoxy-4-quinolinyl)phenol;4-(7-methoxyquinolin-4-yl)-2-methylphenol;CU-CPT-9B;CAS 2165340-32-7 ;TLR8 INHIBITOR;Phenol, 4-(7-methoxy-4-quinolinyl)-2-methyl-
CBNumber:
CB53369684
Molecular Formula:
C17H15NO2
Molecular Weight:
265.31
MDL Number:
MFCD31689252
MOL File:
2165340-32-7.mol
MSDS File:
SDS
Last updated:2026-04-17 13:05:51
Product description Number Pack Size Price
CU-CPT9a 28722 5mg $100
CU-CPT9a 28722 25mg $381
CU-CPT9a 28722 1mg $32
CU-CPT9a 28722 10mg $184
CU-CPT9a C852008 2.5mg $130
More product size
Request For Quotation

4-(7-methoxyquinolin-4-yl)-2-methylphenol Properties

Boiling point 429.7±45.0 °C(Predicted)
Density 1.201±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid
pka 8.47±0.20(Predicted)
color Light yellow to yellow
InChI 1S/C17H15NO2/c1-11-9-12(3-6-17(11)19)14-7-8-18-16-10-13(20-2)4-5-15(14)16/h3-10,19H,1-2H3
InChIKey HNYBTVKYLVLWCB-UHFFFAOYSA-N
SMILES CC1=CC(C2=CC=NC3=CC(OC)=CC=C23)=CC=C1O
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

4-(7-methoxyquinolin-4-yl)-2-methylphenol price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 28722 CU-CPT9a 2165340-32-7 5mg $100 2024-03-01 Buy
Cayman Chemical 28722 CU-CPT9a 2165340-32-7 25mg $381 2024-03-01 Buy
Cayman Chemical 28722 CU-CPT9a 2165340-32-7 1mg $32 2024-03-01 Buy
Cayman Chemical 28722 CU-CPT9a 2165340-32-7 10mg $184 2024-03-01 Buy
TRC C852008 CU-CPT9a 2165340-32-7 2.5mg $130 2021-12-16 Buy
Product number Packaging Price Buy
28722 5mg $100 Buy
28722 25mg $381 Buy
28722 1mg $32 Buy
28722 10mg $184 Buy
C852008 2.5mg $130 Buy

4-(7-methoxyquinolin-4-yl)-2-methylphenol Chemical Properties,Uses,Production

Uses

CU-CPT9a is a potent TLR8 inhibitor (IC50 = 0.5 nM and Kd = 21 nM). Stabilizes the TLR8 dimer in its resting state, preventing activation. Suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.

Biological Activity

CU-CPT9a is a potent and selective inhibitor of Toll-like receptor 8 (TLR8). It binds to TLR8 at a site different from current small-molecule TLR7/8 agonists, stabilizing the TLR8 dimer in its resting state, thus preventing TLR8 activation It exhibited an IC50 value of 0.5 nM and blocked TLR8 activation induced by either resiquimod (R848) or ssRNA without affecting the closely related TLR7 or cells expressing other TLRs. CU-CPT9a also suppressed TNF-α levels in a dose-dependent manner in cells from patients with rheumatoid arthritis.

IC 50

TLR8: 0.5 nM (IC50)

storage

Store at -20°C

4-(7-methoxyquinolin-4-yl)-2-methylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

4-(7-methoxyquinolin-4-yl)-2-methylphenol Suppliers

Global( 79)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30227 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39040 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5221 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Labnetwork lnc. 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58

View Lastest Price from 4-(7-methoxyquinolin-4-yl)-2-methylphenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CU-CPT-9a pictures 2026-04-17 CU-CPT-9a
2165340-32-7
 US $34.00-128.00 / mg 99.01% 10g TargetMol Chemicals Inc.
  • CU-CPT-9a pictures
  • CU-CPT-9a
    2165340-32-7
  • US $34.00-128.00 / mg
  • 99.01%
  • TargetMol Chemicals Inc.

4-(7-methoxyquinolin-4-yl)-2-methylphenol Spectrum

4-(7-methoxyquinolin-4-yl)-2-methylphenol(2165340-32-7)1HNMR

2165340-32-7(4-(7-methoxyquinolin-4-yl)-2-methylphenol)Related Search:

Tilorone dihydrochloride CU-CPT17e CU-CPT-8m CU-CPT-9a
4-(7-methoxyquinolin-4-yl)-2-methylphenol CU-CPT-9B, CPD2004 CU-CPT-9b 2-Methyl-4-(7-methoxy-4-quinolinyl)phenol cas 2165340-32-7 CU-CPT-9B;CAS 2165340-32-7 ;TLR8 INHIBITOR Phenol, 4-(7-methoxy-4-quinolinyl)-2-methyl- CU-CPT9a >=98% (HPLC) Toll-like Receptor (TLR),inhibit,Inhibitor,CU CPT 9a,CUCPT9a CU-CPT-9a, 10 mM in DMSO (7-methoxyquinolin-4-yl)-2-methylphenol 2165340-32-7