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N'-Cbz-L-ornithine

N'-Cbz-L-ornithine structure

CAS No.: 3304-51-6

Chemical Name:: N'-Cbz-L-ornithine

Synonyms: Orn(Z);Z-ORN-OH;H-ORN(Z)-OH;N-ORN(Z)-OH;l-orn(z)-oh;L-Orn(Cbz)-OH;N-D-CBZ-L-ORN;H-L-ORN(Z)-OH;H-ORN(CBZ)-OH;N5-Cbz-Orn-OH

CBNumber:: CB5343696

Molecular Formula:: C13H18N2O4

Molecular Weight:: 266.29

MDL Number:: MFCD00037220

MOL File:: 3304-51-6.mol

Last updated:2025-07-24 18:13:48

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N'-Cbz-L-ornithine Properties

Melting point	248-252℃
Boiling point	492.2±45.0 °C(Predicted)
Density	1.234±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Acidic Alcohol (Sparingly), Aqueous Acid (Slightly)
pka	2.51±0.24(Predicted)
form	Solid
color	White
CAS DataBase Reference	3304-51-6(CAS DataBase Reference)
UNSPSC Code	12352209

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

WGK Germany

NFPA 704

	1
0		0

N'-Cbz-L-ornithine price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	O671015	L-Orn(Z)-OH	3304-51-6	1g	$45	2021-12-16	Buy
Iris Biotech GmbH	HAA1227	H-L-Orn(Z)-OH	3304-51-6	25g	$128.25	2021-12-16	Buy
American Custom Chemicals Corporation	AAA0001708	ORN(CBZ)-OH 95.00%	3304-51-6	1G	$149.63	2021-12-16	Buy
chempep	181515	Z-Orn-OH	3304-51-6	5g	$175	2021-12-16	Buy
Activate Scientific	AS112891	H-Orn(Z)-OH 97%	3304-51-6	100g	$195	2021-12-16	Buy

Product number	Packaging	Price	Buy
O671015	1g	$45	Buy
HAA1227	25g	$128.25	Buy
AAA0001708	1G	$149.63	Buy
181515	5g	$175	Buy
AS112891	100g	$195	Buy

N'-Cbz-L-ornithine Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

L-Orn(Z)-OH is used as a reactant in the synthesis of cyclic aminohexapeptides which showed antifungal activity.

Synthesis

3184-13-2

501-53-1

3304-51-6

The general procedure for the synthesis of (S)-2-amino-5-(((benzyloxy)carbonyl)amino)pentanoic acid from L-ornithine hydrochloride and benzyl chloroformate was as follows: 7.5 g of L-ornithine hydrochloride was dissolved in 89 mL of 0.5 mol/L sodium hydroxide solution, 5.55 g of anhydrous copper sulfate was added, and the reaction was carried out for 15 minutes. Subsequently, 6.15 g of anhydrous potassium carbonate and 8.2 mL of benzyl chloroformate were added and the reaction mixture was stirred at room temperature overnight. After completion of the reaction, the filtrate was washed to give a blue solid. The solid was treated with saturated disodium ethylenediaminetetraacetic acid solution, which was first heated to reflux for 2 hours and then left at room temperature overnight. Finally, the filtrate was filtered and dried to give a white solid product in 83% yield.

References

[1] Patent: CN104788431, 2017, B. Location in patent: Paragraph 0055; 0056
[2] Journal of Labelled Compounds and Radiopharmaceuticals, 2009, vol. 52, # 2, p. 29 - 32
[3] Tetrahedron, 1999, vol. 55, # 33, p. 10201 - 10220
[4] Journal of the Chemical Society [Section] C: Organic, 1971, p. 3743 - 3748
[5] Journal of Agricultural and Food Chemistry, 1999, vol. 47, # 3, p. 939 - 944

N'-Cbz-L-ornithine Preparation Products And Raw materials

Raw materials

L(+)-Ornithine hydrochloride Benzyl chloroformate

Preparation Products

(2S)-5-amino-2-(tert-butoxycarbonylamino)-pentanoic acid tert-butyl ester TOS-ARG-OH

N'-Cbz-L-ornithine Suppliers

Global( 213)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Hubei Jusheng Technology Co.,Ltd.	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
GL Biochem (Shanghai) Ltd.	58
GL Biochem(Binhai) Ltd.	58

N'-Cbz-L-ornithine Spectrum

N'-Cbz-L-ornithine(3304-51-6)¹HNMR N'-Cbz-L-ornithine(3304-51-6)¹HNMR

3304-51-6(N'-Cbz-L-ornithine)Related Search:

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H-Orn(Boc)-OBzl·HCl H-ORN(FMOC)-OH H-Orn(Tfa)-OH H-Orn(Trt)-OH H-Orn(Boc)-OtBu.HCl

N(delta)-acetylornithine Ethyl L-ornithine dihydrochloride H-ORN(BOC)-OME HCL

1of4

L-ORNITHINE(CBZ) H-ORN(Z)-OH H-ORN(CBZ)-OH Orn(Z) L-Orn(Cbz)-OH Nd-Z-L-ornithine≥ 98% (HPLC) (2S)-2-amino-5-{[(benzyloxy)carbonyl]amino}pentanoic acid N5-Cbz-L-ornithine H-L-ORN(Z)-OH N-D-CBZ-L-ORN N-DELTA-Z-L-ORNITHINE N-DELTA-BENZYLOXYCARBONYL-L-ORNITHINE N-DELTA-CARBOBENZOXY-L-ORNITHINE N-DELTA-CARBOBENZYLOXY-L-ORNITHINE N-DELTA-CBZ-L-ORNITHINE N-ORN(Z)-OH ORNITHINE(Z)-OH Z-ORN-OH N_δ-Cbz-L-ornithine N-?-CBZ-L-Ornithine N-?-Carbobenzyloxy-L-ornithine N-5-BENZYLOXYCARBONYL-L-ORNITHINE N5-benzyloxycarbonyl-L-ornithine N--Benzyloxycarbonyl-L-ornithine l-orn(z)-oh N'-Cbz-L-ornithine Z-L-ORNITHINE extrapure (S)-2-Amino-5-[[(benzyloxy)carbonyl]amino]pentanoic acid N5-[(Phenylmethoxy)carbonyl]-L-ornithine N5-Cbz-Orn-OH 2-amino-5-(benzyloxycarbonylamino)valeric acid 2-amino-5-(phenylmethoxycarbonylamino)pentanoic acid 2-azanyl-5-(phenylmethoxycarbonylamino)pentanoic acid N-D-BENZYLOXYCARBONYL-LORNITHINE N-Δ-Z-L-ORNITHINE Ornithine, N5-[(phenylmethoxy)carbonyl]- L-Ornithine, N5-[(phenylmethoxy)carbonyl]- N^d-Benzyloxycarbonyl-L-ornithine,98% N'-Cbz-L-ornithine USP/EP/BP 3304-51-6 Modified Amino Acids I - Z BioChemical Biochemicals and Reagents Amino Acids and Peptides Ornithine [Org] Amino Acids and Derivatives Z-Amino acid series Amino Acids