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2-METHYLGLUTARONITRILE

2-METHYLGLUTARONITRILE structure

CAS No.: 4553-62-2

Chemical Name:: 2-METHYLGLUTARONITRILE

Synonyms: MGN;Diacrylonitrile;2,4-Dicyanobutane;1,3-DICYANOBUTANE;METHYLGLUTARONITRILE;2-METHYLGLUTARONITRILE;2-methylpentanedinitrile;2-methyl-pentanedinitril;1,3-Butanedicarbonitrile;2-Methyl pentanedinitrile

CBNumber:: CB5349683

Molecular Formula:: C6H8N2

Molecular Weight:: 108.14

MDL Number:: MFCD00001875

MOL File:: 4553-62-2.mol

MSDS File:: SDS

Last updated:2026-04-10 10:27:19

Product description	Number	Pack Size	Price
2-Methylglutaronitrile 99%	427519	250ml	$71.4
2-Methylglutaronitrile 99%	427519	1l	$188
2-Methylglutaronitrile >98.0%(GC)	M0331	10g	$17
2-Methylglutaronitrile >98.0%(GC)	M0331	25g	$30
2-Methylglutaronitrile >98.0%(GC)	M0331	500g	$75
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2-METHYLGLUTARONITRILE Properties

Melting point	−45 °C(lit.)
Boiling point	269-271 °C(lit.)
Density	0.95 g/mL at 25 °C(lit.)
vapor pressure	1.9Pa at 20℃
refractive index	n20/D 1.434(lit.)
Flash point	>230 °F
storage temp.	Store at +2°C to +8°C.
solubility	water: soluble
form	clear liquid
color	Colorless to Light yellow to Light orange
explosive limit	0.3-3.25%(V)
Water Solubility	52.3g/L at 20℃
BRN	1741955
Henry's Law Constant	3.3×10² mol/(m³Pa) at 25℃, HSDB (2015)
InChI	1S/C6H8N2/c1-6(5-8)3-2-4-7/h6H,2-3H2,1H3
InChIKey	FPPLREPCQJZDAQ-UHFFFAOYSA-N
SMILES	CC(CCC#N)C#N
LogP	0.46 at 20℃
CAS DataBase Reference	4553-62-2(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	EJX3MSL725
EPA Substance Registry System	2-Methylglutaronitrile (4553-62-2)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301+H311-H330

Precautionary statements

P280-P301+P310+P330-P302+P352+P312-P304+P340+P310

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xn,T

Risk Statements

20/21/22-23/25-21

Safety Statements

36/37-45-36/37/39

RIDADR

3276

WGK Germany

RTECS

YV8140000

TSCA

TSCA listed

HS Code

2926.90.5050

HazardClass

6.1(b)

PackingGroup

III

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications

Acute Tox. 2 Inhalation
Acute Tox. 3 Dermal
Acute Tox. 3 Oral

Hazardous Substances Data

4553-62-2(Hazardous Substances Data)

NFPA 704

	1
3		0

2-METHYLGLUTARONITRILE price More Price(12)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	427519	2-Methylglutaronitrile 99%	4553-62-2	250ml	$71.4	2026-03-19	Buy
Sigma-Aldrich	427519	2-Methylglutaronitrile 99%	4553-62-2	1l	$188	2026-03-19	Buy
TCI Chemical	M0331	2-Methylglutaronitrile >98.0%(GC)	4553-62-2	10g	$17	2026-03-19	Buy
TCI Chemical	M0331	2-Methylglutaronitrile >98.0%(GC)	4553-62-2	25g	$30	2023-06-20	Buy
TCI Chemical	M0331	2-Methylglutaronitrile >98.0%(GC)	4553-62-2	500g	$75	2023-06-20	Buy

Product number	Packaging	Price	Buy
427519	250ml	$71.4	Buy
427519	1l	$188	Buy
M0331	10g	$17	Buy
M0331	25g	$30	Buy
M0331	500g	$75	Buy

2-METHYLGLUTARONITRILE Chemical Properties,Uses,Production

Uses

2-Methylglutaronitrile (MGN) may be used in the synthesis of 1,5-dimethyl-2-piperidone (1,5-DMPD) by chemoenzymatic process.

General Description

Amber liquid.

Air & Water Reactions

Water soluble.

Reactivity Profile

Nitriles, such as 2-METHYLGLUTARONITRILE, may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids.

Health Hazard

ACUTE/CHRONIC HAZARDS: 2-METHYLGLUTARONITRILE is readily absorbed through the skin.

Fire Hazard

2-METHYLGLUTARONITRILE is combustible.

2-METHYLGLUTARONITRILE synthesis

Synthesis of 2-METHYLGLUTARONITRILE from HYDROGEN CYANIDE and 3-PENTENENITRILE

2-METHYLGLUTARONITRILE Preparation Products And Raw materials

Raw materials

3-CYANOPROPIONALDEHYDE DIMETHYL ACETAL Methanol carbon monoxide Propionitrile Acrylonitrile

Preparation Products

5-METHYL-2-PIPERIDINONE 2,5,6-trichloronicotinaMide

2-METHYLGLUTARONITRILE Suppliers

Global( 138)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21592	55
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Xi'an MC Biotech, Co., Ltd.	029-89275612 +8618991951683	mcbio_sales@163.com	China	2251	58
Alfa Chemistry		info@alfa-chemistry.com	United States	2344	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Shaanxi Didu New Materials Co. Ltd	+86-86-17392712779 +8617392712697	1022@dideu.com	China	8401	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
ZHEJIANG JIUZHOU CHEM CO., LTD	+86-0576225566889 +86-13454675544	admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com	China	12272	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Xi'an MC Biotech, Co., Ltd.	58
Alfa Chemistry	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Shaanxi Didu New Materials Co. Ltd	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
ZHEJIANG JIUZHOU CHEM CO., LTD	58

View Lastest Price from 2-METHYLGLUTARONITRILE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-26	2-Methylglutaronitrile 4553-62-2	US $0.00-0.00 / Kg	1KG	99.0%+	1000 tons	Shaanxi Dideu Medichem Co. Ltd
	2020-01-09	2-METHYLGLUTARONITRILE 4553-62-2	US $1.00 / ASSAYS	1ASSAYS	85.0-99.8%	20tons	Career Henan Chemical Co

2-Methylglutaronitrile
4553-62-2
US $0.00-0.00 / Kg
99.0%+
Shaanxi Dideu Medichem Co. Ltd

2-METHYLGLUTARONITRILE
4553-62-2
US $1.00 / ASSAYS
85.0-99.8%
Career Henan Chemical Co

2-METHYLGLUTARONITRILE Spectrum

2-METHYLGLUTARONITRILE(4553-62-2)MS 2-METHYLGLUTARONITRILE(4553-62-2)¹HNMR 2-METHYLGLUTARONITRILE(4553-62-2)IR1 2-METHYLGLUTARONITRILE(4553-62-2)Raman

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