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3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE

CAS No.
2538-50-3
Chemical Name:
3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE
Synonyms
propan-1-one hydrochL;Atomoxetine Impurity 34;3-Methylaminopropiophenone;Atomoxetine Impurity 5 HCl;3-(METHYLAMINO)PROPIOPHENONE HCL;3-Methylamino-1-Phenyl-1-Acetone HCl;3-Methylaminophenylpropa hydrochloride;3-Methylaminophenylpropanone hydrochloride;3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE;N,N-dibutylbenzene-1,4-diaMine hydrochloride
CBNumber:
CB5366385
Molecular Formula:
C10H14ClNO
Molecular Weight:
199.68
MDL Number:
MFCD08063896
MOL File:
2538-50-3.mol
Last updated:2025-07-24 18:13:48

3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE Properties

Melting point 139-141 °C(Solv: acetone (67-64-1))
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
CAS DataBase Reference 2538-50-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P280-P305+P351+P338-P310

3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M331250 3-(Methylamino)-1-phenylpropan-1-oneHydrochloride 2538-50-3 500mg $70 2021-12-16 Buy
Matrix Scientific 081798 3-(Methylamino)-1-phenylpropan-1-one hydrochloride 97% 2538-50-3 1g $230 2021-12-16 Buy
Matrix Scientific 177010 1-(Methylamino)-3-phenylacetone hydrochloride 2538-50-3 1g $540 2021-12-16 Buy
Matrix Scientific 177010 1-(Methylamino)-3-phenylacetone hydrochloride 2538-50-3 5g $1296 2021-12-16 Buy
Matrix Scientific 081798 3-(Methylamino)-1-phenylpropan-1-one hydrochloride 97% 2538-50-3 10g $1428 2021-12-16 Buy
Product number Packaging Price Buy
M331250 500mg $70 Buy
081798 1g $230 Buy
177010 1g $540 Buy
177010 5g $1296 Buy
081798 10g $1428 Buy

3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

3-(Methylamino)-1-phenylpropan-1-one Hydrochloride can be used for nontoxic non-irritating wood preservative for toys or teaching appliances.

Synthesis

Formaldehyde

50-00-0

Methylamine hydrochloride

593-51-1

Acetophenone

98-86-2

3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE

2538-50-3

Acetophenone (25 mmol), methylamine hydrochloride (27.5 mmol), formaldehyde (35 mmol) and concentrated hydrochloric acid (0.125 mmol) were mixed in ethanol (12.5 mL). The mixture was placed in a sealed container and heated for 20 hours for the reaction. After completion of the reaction, it was cooled to room temperature. The solvent was removed by distillation under reduced pressure, followed by addition of ethyl acetate (25 mL) and continued stirring for 4 hours. The crude product was collected by filtration, washed with ethyl acetate and finally purified by recrystallization from isopropanol to afford the target product 3-(methylamino)-1-phenylpropan-1-one hydrochloride (Product 2a). Yield: 60-70%.

References

[1] Patent: CN103992236, 2016, B. Location in patent: Paragraph 0051-0053
[2] Patent: KR2015/116956, 2015, A. Location in patent: Paragraph 0117-0120
[3] Angewandte Chemie - International Edition, 2005, vol. 44, # 11, p. 1687 - 1689
[4] Angewandte Chemie - International Edition, 2015, vol. 54, # 7, p. 2260 - 2264
[5] Angew. Chem.,

3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE Preparation Products And Raw materials

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View Lastest Price from 3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE pictures 2020-01-19 3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE
2538-50-3
US $3.00 / KG 1KG 98% 1kg,5kg,50kg Career Henan Chemical Co
3-METHYLAMINO-1-PHENYLACETONE HYDROCHLORIDE 3-(METHYLAMINO)PROPIOPHENONE HCL 3-Methylaminopropiophenone 3-Methylamino-1-Phenyl-1-Acetone HCl 3-Methylaminophenylpropanone hydrochloride 1-(Methylamino)-3-phenylacetone hydrochloride 3-(Methylamino)-1-phenyl-1-propanone hydrochloride 1-(MethylaMino)-3-phenylpropan-2-one hydrochloride N,N-dibutylbenzene-1,4-diaMine hydrochloride 3-Methylamino-1-phenylpropan-1-one hydrochloride 3-Methylaminophenylpropanone hydrochloride -(Methylamino)-1-phenyl-1-propanone hydrochloride 1-(methylamino)-3-phenyl-2-propanone hydrochloride Atomoxetine Impurity 5 HCl propan-1-one hydrochL 3-methylamino-1-phenyl-1-acetone hydrochloride Atomoxetine Impurity 34 3-Methylaminophenylpropa hydrochloride 2538-50-3