4-Aminopyridine-2-carboxylic acid
- CAS No.
- 100047-36-7
- Chemical Name:
- 4-Aminopyridine-2-carboxylic acid
- Synonyms
- 4-AMINOPICOLINIC ACID;IFLAB-BB F1926-0040;4-Aminopicolinic acid - [A12444];4-AMINOPYRIDINE-2-CARBOXYLIC ACID;2-Pyridinecarboxylic acid, 4-amino-;4-Aminopyridine-2-carboxylic acid 97%;4-Aminopyridine-2-carboxylic acid ,97%;2-Pyridinecarboxylicacid,4-amino-(9CI);4-Aminopyridine-2-carboxylic acid USP/EP/BP;100047-36-4-aminopyridine-2-carboxylic Acid7
- CBNumber:
- CB5401109
- Molecular Formula:
- C6H6N2O2
- Molecular Weight:
- 138.12
- MDL Number:
- MFCD02685671
- MOL File:
- 100047-36-7.mol
- MSDS File:
- SDS
| Melting point | 265 °C |
|---|---|
| Boiling point | 446.3±30.0 °C(Predicted) |
| Density | 1.417±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Acetone, Ethanol, Methanol |
| form | Solid |
| pka | 1.37±0.50(Predicted) |
| Appearance | Off-white to yellow Solid |
| InChI | InChI=1S/C6H6N2O2/c7-4-1-2-8-5(3-4)6(9)10/h1-3H,(H2,7,8)(H,9,10) |
| InChIKey | JRZBTJVSAANBEV-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)=NC=CC(N)=C1 |
| CAS DataBase Reference | 100047-36-7(CAS DataBase Reference) |
| UNSPSC Code | 12352106 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301+P312+P330 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22-36/37/38-20/21/22 |
| Safety Statements | 50A-24/25-36/37/39 |
| RIDADR | 2761 |
| Hazard Note | Irritant |
| HS Code | 29333990 |
4-Aminopyridine-2-carboxylic acid price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS007808 | 4-aminopyridine-2-carboxylic acid Aldrich | 100047-36-7 | 250mg | $73.1 | 2025-07-31 | Buy |
| TRC | A627805 | 4-AminopicolinicAcid | 100047-36-7 | 5g | $580 | 2021-12-16 | Buy |
| TRC | A627805 | 4-AminopicolinicAcid | 100047-36-7 | 25g | $2475 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK142952 | 4-aminopyridine-2-carboxylic acid 97% | 100047-36-7 | 5g | $560 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 6759 | 4-AminopicolinicAcid | 100047-36-7 | 50mg | $1760 | 2021-12-16 | Buy |
4-Aminopyridine-2-carboxylic acid Chemical Properties,Uses,Production
Description
4-Aminopyridine-2-carboxylic acid is an organic synthetic reagent used in the preparation of 4-amino-6-(heterocyclic)pyridine carboxylic acid esters, 4-amino-2,6-dimethylnicotinic acid esters and amides.
Chemical Properties
White solid
Uses
4-Aminopyridine-2-carboxylic acid can be a useful synthetic intermediate
Synthesis
1918-02-1
100047-36-7
General procedure for the synthesis of 4-aminopyridine-2-carboxylic acid from 4-amino-3,5,6-trichloropyridine-2-carboxylic acid: a thick suspension formed by Picloram (8 g, 33 mmol) and 10% Pd/C (1.2 g) in a 10% aqueous LiOH solution (44 mL) was purged twice with hydrogen, and then under a hydrogen atmosphere (45 PSI) at 40°C for 4 hours with stirring. Subsequently, the mixture was heated to 70°C and maintained for 12 hours. Upon completion of the reaction, the cooled suspension was filtered through diatomaceous earth. The filtrate was acidified to pH=3 in concentrated HCl (~3.5 mL), at which point a precipitate was generated. The solid product was collected by filtration and dried overnight under high vacuum to give the final 4-aminopyridine-2-carboxylic acid as a beige solid (4.6 g, 99% yield).LCMS analysis showed m/z 139.1 (M + H)+ with a retention time of 0.21 minutes.
References
[1] Patent: WO2012/3576, 2012, A1. Location in patent: Page/Page column 96
4-Aminopyridine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3390 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from 4-Aminopyridine-2-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-19 | 4-Aminopyridine-2-carboxylic acid
100047-36-7
|
US $10.00 / ASSAYS | 1ASSAYS | 99% | 1 ton | RongNa Biotechnology Co.,Ltd | |
 |
2020-01-08 | 4-Aminopyridine-2-carboxylic acid
100047-36-7
|
US $0.01 / KG | 1KG | 98%;99% | 1kg； 5kg；10kg；25kg | Career Henan Chemical Co |
-
- 4-Aminopyridine-2-carboxylic acid
100047-36-7
- US $10.00 / ASSAYS
- 99%
- RongNa Biotechnology Co.,Ltd
-
- 4-Aminopyridine-2-carboxylic acid
100047-36-7
- US $0.01 / KG
- 98%;99%
- Career Henan Chemical Co
