SPINOSAD
- CAS No.
- 168316-95-8
- Chemical Name:
- SPINOSAD
- Synonyms
- SPINOS;Spinosads;oxysaccharin;Spinosad [iso];Spinosad (CRM);Spinosad Standard;Tracer naturalyte;SPINOSAD USP/EP/BP;C16972830 Spinosad;Spinosad in Acetone
- CBNumber:
- CB5416798
- Molecular Formula:
- C41H65NO10
- Molecular Weight:
- 731.96
- MDL Number:
- MFCD01753923
- MOL File:
- 168316-95-8.mol
- MSDS File:
- SDS
| Melting point | 110℃ |
|---|---|
| storage temp. | 0-6°C |
| solubility | Ethanol: 1 mg/ml |
| form | Solid |
| color | White to off-white |
| FDA UNII | XPA88EAP6V |
| EPA Substance Registry System | Spinosad (168316-95-8) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SPINOSAD price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CRM51599 | Spinosad certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | 168316-95-8 | 50 mg | $372 | 2025-07-31 | Buy |
| Sigma-Aldrich | 33706 | Spinosad | 168316-95-8 | 50mg | $307 | 2025-07-31 | Buy |
| Cayman Chemical | 25649 | Spinosad ≥95% | 168316-95-8 | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 25649 | Spinosad ≥95% | 168316-95-8 | 10mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 25649 | Spinosad ≥95% | 168316-95-8 | 25mg | $172 | 2024-03-01 | Buy |
SPINOSAD Chemical Properties,Uses,Production
Description
Spinosad is a naturally-occurring insecticide found in the the soil bacterium S. spinosa. It is a mixture of the macrocyclic lactones spinosyn A and spinosyn D , which act as agonists of insect nicotinic acetylcholinesterase receptors (nAChRs). Oral administration of spinosad induces toxicity in fruit flies including C. capitata, B. curcurbitae, and B. dorsalis (LC50s = 2.8-4.2, 4.3-5.5, and 3.1-3.3 μg/ml, respectively) but has low toxicity in vertebrates. It also inhibits canine P-glycoprotein (P-gp; IC50 = 0.2 μg/ml). Formulations containing spinosad have been used in the agricultural and veterinary control of insects.
Uses
Insecticide.
Definition
Isolated from Saccharopolyspora spinosa (Actinomycetes).
Hazard
A poison by inhalation. Moderately toxic by ingestion.
in vivo
Spinosad is a natural mixture of the pediculicidal tetracyclic macrolides spinosyn A and spinosyn D. Spinosad 0.9% mainly interferes with nicotinic acetylcholine receptors in insects, thereby producing neuronal excitation that results in paralysis of lice from neuromuscular fatigue after extended periods of hyperexcitation. Spinosad 0.9% kills both permethrin-susceptible and permethrin-resistant populations of lice. It is also ovicidal, killing both eggs (nits) and lice[5].
Spinosad causes in vivo oxidative effects in the brain of Oreochromis niloticus. Spinosad causes elevations in the contents of tGSH, GSH, GSSG, Hsp70, and reductions in the ratio of GSH/GSSG and GPx activity and an induction in the GR (glutathione reducta) activity. Spinosad has oxidative effects in the brain tissue by altering the parameters in GSH-related antioxidant system and Hsp70[6].
References
[1] WESLEY J. MAGUIRE*. Comprehensive Determination of Unregulated Pesticide Residues in Oregon Cannabis Flower by Liquid Chromatography Paired with Triple Quadrupole Mass Spectrometry and Gas Chromatography Paired with Triple Quadrupole Mass Spectrometry[J]. Journal of Agricultural and Food Chemistry, 2019, 67 46: 12670-12674. DOI: 10.1021/acs.jafc.9b01559
[2] D. T. VO. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals[J]. Journal of veterinary pharmacology and therapeutics, 2010, 33 4: 315-322. DOI: 10.1111/j.1365-2885.2010.01160.x
[3] JOHN D STARK Neil M Roger Vargas. Toxicity of spinosad in protein bait to three economically important tephritid fruit fly species (Diptera: Tephritidae) and their parasitoids (Hymenoptera: Braconidae).[J]. Journal of Economic Entomology, 2004, 97 3: 911-915. DOI: 10.1603/0022-0493(2004)097[0911:tosipb]2.0.co;2
[4] T S AMARAL. Short-term effects of a spinosyn’s family insecticide on energy metabolism and liver morphology in frugivorous bats Artibeus lituratus (Olfers, 1818).[J]. Brazilian Journal of Biology, 2012, 72 2: 299-304. DOI: 10.1590/s1519-69842012000200010
[5] SCHRICKX J A. Spinosad is a potent inhibitor of canine P-glycoprotein[J]. Veterinary journal, 2014, 200 1: Pages 195-196. DOI: 10.1016/j.tvjl.2014.01.012
SPINOSAD Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Wuhan Fortuna Chemical Co.,Ltd | +86-2759207851; +8618007136271 | hk@fortunachem.com | China | 5991 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21620 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | FandaChem@Gmail.com | China | 1631 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Beijing Yibai Biotechnology Co., Ltd | 0086-182-6772-3597 | sales04@yibaibiotech.com | CHINA | 419 | 58 |
View Lastest Price from SPINOSAD manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-23 | Spinosad
168316-95-8
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2025-09-23 | Spinosad
168316-95-8
|
US $0.00-0.00 / KG | 1KG | 90%-95%TC | 20TONS | Wuhan Fortuna Chemical Co.,Ltd | |
 |
2025-09-19 | Spinosad
168316-95-8
|
US $97.00-41.00 / mg | 99.06% | 10g | TargetMol Chemicals Inc. |
