5-METHYL-DL-TRYPTOPHAN
- CAS No.
- 951-55-3
- Chemical Name:
- 5-METHYL-DL-TRYPTOPHAN
- Synonyms
- H-Trp(5-Me)-OH;H-5-ME-DL-TRP-OH;H-DL-Trp(5-Me)-OH;TIMTEC-BB SBB003368;5-METHYL-DL-TRYPTOPH;DL-5-METHYLTRYPTOPHAN;5-METHYL-DL-TRYPTOPHAN;Tryptophan Impurity 101;5-Methyl-DL-tryptophan>5-Methyl-DL-tryptophan,98%
- CBNumber:
- CB5417694
- Molecular Formula:
- C12H14N2O2
- Molecular Weight:
- 218.25
- MDL Number:
- MFCD00005652
- MOL File:
- 951-55-3.mol
| Melting point | ~275 °C (dec.) |
|---|---|
| Boiling point | 358.94°C (rough estimate) |
| alpha | [α]D20 -1～+1゜ (c=1, dil. HCl) |
| Density | 1.1402 (rough estimate) |
| refractive index | 1.6660 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | Powder |
| pka | 2.26±0.10(Predicted) |
| color | Off-white |
| optical activity | 0.20°(C=1.00g/100ml HCL) |
| BRN | 20225 |
| CAS DataBase Reference | 951-55-3(CAS DataBase Reference) |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
5-METHYL-DL-TRYPTOPHAN price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M0534 | 5-Methyl-DL-tryptophan tryptophan analog | 951-55-3 | 250mg | $250.25 | 2025-07-31 | Buy |
| Sigma-Aldrich | M0534 | 5-Methyl-DL-tryptophan tryptophan analog | 951-55-3 | 1g | $545 | 2025-07-31 | Buy |
| TCI Chemical | M0452 | 5-Methyl-DL-tryptophan >98.0%(T)(HPLC) | 951-55-3 | 100mg | $69 | 2025-07-31 | Buy |
| TCI Chemical | M0452 | 5-Methyl-DL-tryptophan >98.0%(T)(HPLC) | 951-55-3 | 1g | $563 | 2025-07-31 | Buy |
| Usbiological | 284106 | 5-Methyl-DL-tryptophan | 951-55-3 | 250mg | $375 | 2021-12-16 | Buy |
5-METHYL-DL-TRYPTOPHAN Chemical Properties,Uses,Production
Chemical Properties
off-white powder
Uses
peptide synthesis
Definition
ChEBI: 5-methyltryptophan is a tryptophan derivative that is tryptophan substituted by a methyl group at position 5 of the indole ring. It is a non-proteinogenic alpha-amino acid and a tryptophan derivative.
Biological Activity
5-Methyl-DL-tryptophan inhibits the synthesis of anthranilate compounds th at are the first steps in the biosynthesis of tryptophan in Neurospora crassa. 5-Methyl-DL-tryptophan is a corepressor of the E. coli trp repressor.', '5-Methyl-DL-tryptophan may be used to select genetic mutants of PS strain of Methanococcus voltae (archaebacteria). 5-Methyl-tryptophan is a repressor trp operon expression. 5-Methyl-tryptophan is a substrate for tryptophanase. 5-Methyl-tryptophan inhibits the induction of anthranilate synthase activity by elicitors in oats.
Purification Methods
Crystallise dl-5-methyltryptophan from aqueous EtOH after dissolving it in aqueous NaOH, precipitating with AcOH, filtering the solid off and drying for 24hours at 50o. [Jackman & Archer J Am Chem Soc 68 2105 1946, Beilstein 22 IV 6815.] The picrate crystallises from MeOH with m 202o(dec). The N-phenylcarbamoyl derivative crystallises from aqueous MeOH with m 202o. [Gordon & Jackson J Biol Chem 110 151, 154 1935.]
5-METHYL-DL-TRYPTOPHAN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20424 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Wuhan Fortuna Chemical Co.,Ltd | +86-2759207851; +8618007136271 | hk@fortunachem.com | China | 5991 | 58 |
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