ChemicalBook >> CAS DataBase List >>3-Fluoropyridine-4-carboxylic acid
3-Fluoropyridine-4-carboxylic acid
- CAS No.
- 393-53-3
- Chemical Name:
- 3-Fluoropyridine-4-carboxylic acid
- Synonyms
- 3-FLUOROISONICOTINIC ACID;3-FLUOROISON;3-fluoroisonic acid;3-Fluoroisonicotinic;3-FLUORONICOTINIC ACID;3- fluorineisonicotinic acid;3-Fluoro-4-pyridinecarboxylic;3-Fluoroisonicotinic Acid, 97+%;3-Fluoropyridine-4-carboxylicaci;3-Fluoropyridin-4-carboxylic acid
- CBNumber:
- CB5433900
- Molecular Formula:
- C6H4FNO2
- Molecular Weight:
- 141.1
- MDL Number:
- MFCD03789251
- MOL File:
- 393-53-3.mol
- MSDS File:
- SDS
Last updated:2026-01-13 11:22:54
| Product description | Number | Pack Size | Price |
| 3-Fluoro-4-pyridinecarboxylic acid 97% | 638757 | 1g | $30.2 |
| 3-Fluoro-4-pyridinecarboxylic acid 97% | 638757 | 10g | $278 |
| 3-Fluoroisonicotinic Acid min. 98.0 % | F0477 | 5G | $48 |
| 3-Fluoroisonicotinic Acid min. 98.0 % | F0477 | 25G | $144 |
| 3-Fluoroisonicotinicacid | F592118 | 100mg | $45 |
| More product size | |||
| Melting point | 251-254°C (dec.) |
|---|---|
| Boiling point | 360.0±22.0 °C(Predicted) |
| Density | 1.419±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 2.85±0.10(Predicted) |
| form | solid |
| color | White to off-white |
| BRN | 383678 |
| InChI | 1S/C6H4FNO2/c7-5-3-8-2-1-4(5)6(9)10/h1-3H,(H,9,10) |
| InChIKey | POLXLLIQWDBJMD-UHFFFAOYSA-N |
| SMILES | OC(=O)c1ccncc1F |
| CAS DataBase Reference | 393-53-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi,F | |||||||||
| Risk Statements | 36/37/38-10 | |||||||||
| Safety Statements | 26-36-16 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| NFPA 704 |
|
3-Fluoropyridine-4-carboxylic acid price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 638757 | 3-Fluoro-4-pyridinecarboxylic acid 97% | 393-53-3 | 1g | $30.2 | 2023-06-20 | Buy |
| Sigma-Aldrich | 638757 | 3-Fluoro-4-pyridinecarboxylic acid 97% | 393-53-3 | 10g | $278 | 2023-06-20 | Buy |
| TCI Chemical | F0477 | 3-Fluoroisonicotinic Acid min. 98.0 % | 393-53-3 | 5G | $48 | 2026-03-19 | Buy |
| TCI Chemical | F0477 | 3-Fluoroisonicotinic Acid min. 98.0 % | 393-53-3 | 25G | $144 | 2026-03-19 | Buy |
| TRC | F592118 | 3-Fluoroisonicotinicacid | 393-53-3 | 100mg | $45 | 2021-12-16 | Buy |
3-Fluoropyridine-4-carboxylic acid Chemical Properties,Uses,Production
Synthesis
124-38-9
393-53-3
3-Fluoropyridine (25 g, 257 mmol) was slowly added dropwise to a solution of tetrahydrofuran (600 mL) containing butyl lithium (270 mmol) and diisopropylamine (27.4 g, 271 mmol) at -78 °C. The reaction mixture was stirred continuously at this temperature for 1 hour. Subsequently, crushed dry ice was added to the reaction system and gradually warmed to room temperature over 1 hour. Upon completion of the reaction, the pH of the reaction solution was adjusted to 5 with an aqueous solution of hydrogen chloride and acidified. The resulting precipitate was collected by filtration and dried. The final 3-fluoroisonicotinic acid (25.2 g, 179 mmol, 70% yield) was obtained as colorless crystals.
References
[1] Patent: WO2006/36015, 2006, A2. Location in patent: Page/Page column 121-122
3-Fluoropyridine-4-carboxylic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 249)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
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| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
View Lastest Price from 3-Fluoropyridine-4-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 3-Fluoropyridine-4-carboxylic acid
393-53-3
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2022-09-27 | 3-Fluoropyridine-4-carboxylic acid
393-53-3
|
US $0.00 / kg | 1kg | 99% | 1000kg | henan kanbei chemical co.,ltd | |
 |
2022-02-22 | 3-Fluoroisonicotinic acid
393-53-3
|
US $0.00 / KG | 1KG | 98.2% | 100 tons | Honest Joy Holdings Limited |
-
- 3-Fluoropyridine-4-carboxylic acid
393-53-3
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-Fluoropyridine-4-carboxylic acid
393-53-3
- US $0.00 / kg
- 99%
- henan kanbei chemical co.,ltd
-
- 3-Fluoroisonicotinic acid
393-53-3
- US $0.00 / KG
- 98.2%
- Honest Joy Holdings Limited
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3-FLUOROISON
3-Fluoropyridine-4-carboxylicaci
3-Fluoropyridine-4-carboxylic acid ISO 9001：2015 REACH
3-Fluoropyridin-4-carboxylic acid
393-53-3
C6H4FNO2H2O
Building Blocks
Heterocyclic Building Blocks
Pyridines
C6
Fluorine series
Morpholines/Thiomorpholines
Building Blocks
Fluorinated
blocks
Carboxes
FluoroCompounds
Pyridines
Pyridine
Pyridine series
