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PUROMYCIN AMINONUCLEOSIDE

PUROMYCIN AMINONUCLEOSIDE structure

CAS No.: 58-60-6

Chemical Name:: PUROMYCIN AMINONUCLEOSIDE

Synonyms: ARDMA;Nsc3056;Aids000507;Aids-000507;aminonucleoside;3′-Amino-3′-deoxy-N6;3’-Amino-3’-deoxy-N6;aminonucleosidepuromycin;PuroMycin aMinonucleosid;PUROMYCIN AMINONUCLEOSIDE

CBNumber:: CB5455647

Molecular Formula:: C12H18N6O3

Molecular Weight:: 294.31

MDL Number:: MFCD00063462

MOL File:: 58-60-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-22 18:57:36

Product description	Number	Pack Size	Price
Puromycin aminonucleoside	P7130	100mg	$690
Puromycin aminonucleoside	P7130	1g	$4090
Puromycin Aminonucleoside ≥98%	15509	10mg	$69
Puromycin Aminonucleoside ≥98%	15509	25mg	$157
Puromycin Aminonucleoside ≥98%	15509	50mg	$263
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PUROMYCIN AMINONUCLEOSIDE Properties

Melting point	235℃ (Decomposition)
Boiling point	436.08°C (rough estimate)
Density	1.2131 (rough estimate)
refractive index	1.7000 (estimate)
Flash point	>110°(230°F)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	H₂O: 50 mg/mL, clear, slightly yellow
form	liquid
pka	13.26±0.70(Predicted)
color	White
Water Solubility	Soluble in water at 50mg/ml. May require heating
BRN	93902
Stability	Stable for 1 year as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
InChI	1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7+,9+,12-/m1/s1
InChIKey	RYSMHWILUNYBFW-GRIPGOBMSA-N
SMILES	CN(C)c1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H](N)[C@@H]3O
EWG's Food Scores	1
FDA UNII	0Q580U88V8
EPA Substance Registry System	Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl- (58-60-6)
UNSPSC Code	51281912
NACRES	NA.85

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H373
Precautionary statements	P260-P314-P501a
target organs	Kidney
PPE	Eyeshields, Gloves, type N95 (US)
Hazard Codes	Xi,Xn
Risk Statements	48/22
WGK Germany	3
RTECS	AU7337000
F	10-21
TSCA	TSCA listed
HS Code	29419090
Storage Class	11 - Combustible Solids
Hazard Classifications	STOT RE 2

PUROMYCIN AMINONUCLEOSIDE price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P7130	Puromycin aminonucleoside	58-60-6	100mg	$690	2026-04-30	Buy
Sigma-Aldrich	P7130	Puromycin aminonucleoside	58-60-6	1g	$4090	2026-04-30	Buy
Cayman Chemical	15509	Puromycin Aminonucleoside ≥98%	58-60-6	10mg	$69	2026-04-30	Buy
Cayman Chemical	15509	Puromycin Aminonucleoside ≥98%	58-60-6	25mg	$157	2026-04-30	Buy
Cayman Chemical	15509	Puromycin Aminonucleoside ≥98%	58-60-6	50mg	$263	2026-04-30	Buy

Product number	Packaging	Price	Buy
P7130	100mg	$690	Buy
P7130	1g	$4090	Buy
15509	10mg	$69	Buy
15509	25mg	$157	Buy
15509	50mg	$263	Buy

PUROMYCIN AMINONUCLEOSIDE Chemical Properties,Uses,Production

Description

Puromycin aminonucleoside (58-60-6) is the nucleoside moiety of puromycin (Cat.# 10-2100) which does not inhibit protein synthesis or induce apoptosis.1It acts as a glomerular epithelial cell toxin2 and as such is a useful tool for producing animal models of nephropathy3,4, or puromycin aminonucleoside nephrosis (1-2.5 mg/100g rat body weight)5. Active in vivo.

Chemical Properties

White crystal

Uses

Puromycin aminonucleoside is a semi-synthetic derivative of puromycin which lacks the methoxyphenylalanyl moiety. Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin. It does not inhibit protein synthesis or induce apoptosis, but exhibits antitumour properties. Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing integrin expression in cultured glomerular epithelial cells.

Uses

Puromycin Aminonucleoside is an aminonucleoside portion of the antibiotic puromycin.

Definition

ChEBI: Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.

Safety Profile

An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

References

[1] SEK C. CHOW Sten O Iris Peters. Reevaluation of the Role of de Novo Protein Synthesis in Rat Thymocyte Apoptosis[J]. Experimental cell research, 1995, 216 1: Pages 149-159. DOI:10.1006/excr.1995.1019
[2] Puromycin aminonucleoside suppresses integrin expression in cultured glomerular epithelial cells
[3] YUKARI EGASHIRA Hiroo S Shin Nagaki. Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis.[J]. International Journal for Vitamin and Nutrition Research, 2006, 76 1: 28-33. DOI:10.1024/0300-9831.76.1.28
[4] M. HAGIWARA . Mitochondrial dysfunction in focal segmental glomerulosclerosis of puromycin aminonucleoside nephrosis[J]. Kidney international, 2006, 69 7: Pages 1146-1152. DOI:10.1038/sj.ki.5000207
[5] E K LÖWENBORG U B B G Jaremko. Glomerular function and morphology in puromycin aminonucleoside nephropathy in rats.[J]. Nephrology Dialysis Transplantation, 2000, 15 10: 1547-1555. DOI:10.1093/ndt/15.10.1547

PUROMYCIN AMINONUCLEOSIDE synthesis

Synthesis of PUROMYCIN AMINONUCLEOSIDE from 3'-Azido-3'-deoxy-N6,N6-dimethyladenosine

PUROMYCIN AMINONUCLEOSIDE Preparation Products And Raw materials

Raw materials

3'-Azido-3'-deoxy-N6,N6-dimethyladenosine

Preparation Products

PUROMYCIN AMINONUCLEOSIDE Suppliers

Global( 207)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
TopScience Biochemical	00852-68527855	info@itopbiochem.com	China Hong Kong	902	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5742	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Zhejiang Huida Biotech Co., LTD	008613515763466 8615669048680	wendy@huidabiotech.com	CHINA	87	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Jinan Carbotang Biotech Co.,Ltd.	58
BOC Sciences	58
TopScience Biochemical	58
career henan chemical co	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
SIMAGCHEM CORP	58
TargetMol Chemicals Inc.	58
Zhejiang Huida Biotech Co., LTD	58

View Lastest Price from PUROMYCIN AMINONUCLEOSIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-22	Puromycin aminonucleoside 58-60-6	US $39.00-80.00 / mg		99.90%	10g	TargetMol Chemicals Inc.
2025-12-01	PUROMYCIN AMINONUCLEOSIDE 58-60-6	US $0.00 / kg	1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2019-12-20	PUROMYCINAMINONUCLEOSIDE 58-60-6	US $1.00 / KG	1KG	99%	KG/T	Career Henan Chemical Co

Puromycin aminonucleoside
58-60-6
US $39.00-80.00 / mg
99.90%
TargetMol Chemicals Inc.

PUROMYCIN AMINONUCLEOSIDE
58-60-6
US $0.00 / kg
99%
Shaanxi Dideu New Materials Co. Ltd

PUROMYCINAMINONUCLEOSIDE
58-60-6
US $1.00 / KG
99%
Career Henan Chemical Co

PUROMYCIN AMINONUCLEOSIDE Spectrum

PUROMYCIN AMINONUCLEOSIDE(58-60-6)¹HNMR

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PUROMYCIN DIHYDROCHLORIDE PUROMYCIN PUROMYCIN DIHYDROCHLORIDE N6,N6-DIMETHYLADENOSINE PUROMYCIN AMINONUCLEOSIDE

A 201A PUROMYCIN DIHYDROCHLORIDE DIHYDRATE PUROMYCIN DIHYDROCHLORIDE, [8-3H(N)]-

1of4

3’-amino-3’-deoxy-n,n-dimethyl-adenosin 6-(dimethylamino)-9-(3-amino-3-deoxy-beta-d-ribofuranosyl)purine 9-(3-amino-3-deoxy-beta-d-ribofuranosyl)-6-(dimethylamino)-9h-purine aminonucleoside aminonucleosidepuromycin stylomycinaminonucleoside PUROMYCIN AMINONUCLEOSIDE 6-DIMETHYLAMIN-9-[3'-AMINO-3'DEOXYRIBOSYL]-PURINE Puromycin Aminonucleoside, 6-Dimethylamin-9-[3-amino-3deoxyribosyl]-purine 9-(3-Amino-3-deoxy-.beta.-D-ribofuranosyl)-N,N-dimethyl-9H-purin-6-amine Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl- Aids000507 Aids-000507 Nsc3056 PuroMycin aMinonucleosid 3'-DiMethylaMino-3'-deoxyadenosine 3'-AMINO-3'-DEOXY-N6,N6-DIMETHYLADENOSINE 3'-AMINO-3'-DEOXY-N,N-DIMETHYL-ADENOSINE SAN Puromycin-Amino-Nucleoside NSC 3056 Aminonucleoside puromycin PANS (2R,3R,4S,5S)-4-amino-2-(6-(dimethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol Puromycin aminonucleoside Ready Made Solution puromycin aminonucleoside (PAN) 3′-Amino-3′-deoxy-N6 3’-Amino-3’-deoxy-N6,N6-dimethyladenosine, puromycin aminonucleoside (PAN) PUROMYCIN AMINONUCLEOSIDE USP/EP/BP (2R,3R,4S,5S)-4-amino-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolan-3-ol Puromycin Aminonucleoside (NSC-3056) C12H18N6O3 PUROMYCIN AMINONUCLEOSIDE 58-60-6 PUROMYCIN AMINONUCLEOSIDE ARDMA 3’-Amino-3’-deoxy-N6,N6-dimethyl?adenosine 3’-amino-3’-deoxy-n,n-dimethyl-adenosine 3’-Amino-3’-deoxy-N6 Puromycin aminonucleoside, 10 mM in DMSO Puromycin aminonucleoside/58-60-6 1H-Benz[e]indolium, 2-[3-[3-(5-carboxypentyl)-1,3-dihydro-1,1-dimethyl-6,8-disulfo-2H-benz[e]indol-2-ylidene]-1-propen-1-yl]-3-ethyl-1,1-dimethyl-6,8-disulfo-, inner salt 58-60-6 58-60-4 C12H18N6O3 Antibiotics A to Z Antibiotics BioChemical Antibiotics N-S