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2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID structure

CAS No.: 334952-09-9

Chemical Name:: 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID

Synonyms: 6-CARBOXYOXINDOLE;RARECHEM AL BO 0984;6-Carboxyl-2-oxindole;Intedanib Impurity 30;6-OXINDOLECARBOXYLIC ACID;OXINDOLE-6-CARBOXYLIC ACID;2-Oxindole-6-carboxylic acid;2-Oxyindole-6-carboxylic acid;2-Oxo-indoline-6-carboxylic acid;2-oxo-1,3-dihydroindole-6-carboxylic acid

CBNumber:: CB5464274

Molecular Formula:: C9H7NO3

Molecular Weight:: 177.16

MDL Number:: MFCD01415801

MOL File:: 334952-09-9.mol

MSDS File:: SDS

Last updated:2026-05-28 01:19:13

Product description	Number	Pack Size	Price
2-Oxindole-6-carboxylic acid	123002	1.00g	$1386
2-Oxindole-6-carboxylic acid 95+%	X12586	1g	$30
2-Oxindole-6-carboxylic acid 95+%	X12586	5g	$50
2-Oxindole-6-carboxylic acid 95+%	X12586	10g	$90
2-Oxoindoline-6-carboxylic Acid 97%	AA00BY3I	250mg	$5
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2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID Properties

Boiling point	438.1±45.0 °C(Predicted)
Density	1.433±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	3.94±0.20(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H335-H315-H319
Precautionary statements	P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes	Xi
Risk Statements	36
Safety Statements	26
HS Code	2933998090

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	123002	2-Oxindole-6-carboxylic acid	334952-09-9	1.00g	$1386	2026-05-18	Buy
Synthonix	X12586	2-Oxindole-6-carboxylic acid 95+%	334952-09-9	1g	$30	2026-05-06	Buy
Synthonix	X12586	2-Oxindole-6-carboxylic acid 95+%	334952-09-9	5g	$50	2026-05-06	Buy
Synthonix	X12586	2-Oxindole-6-carboxylic acid 95+%	334952-09-9	10g	$90	2026-05-06	Buy
aablocks	AA00BY3I	2-Oxoindoline-6-carboxylic Acid 97%	334952-09-9	250mg	$5	2026-05-28	Buy

Product number	Packaging	Price	Buy
123002	1.00g	$1386	Buy
X12586	1g	$30	Buy
X12586	5g	$50	Buy
X12586	10g	$90	Buy
AA00BY3I	250mg	$5	Buy

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID Chemical Properties,Uses,Production

Synthesis

14192-26-8

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID

334952-09-9

General procedure for the synthesis of 2-oxoindoline-6-carboxylic acid from methyl 2-oxoindoline-6-carboxylate: Sodium hydroxide solution (1N, 20 mL) was added to a solution of 2-oxoindoline-6-carboxylic acid methyl ester (2 g, 10.46 mmol, 1.00 equiv) in methanol (20 mL). The reaction mixture was stirred at 80 °C for 2 hours. After completion of the reaction, the mixture was cooled to 30 °C, diluted with 50 mL of water and extracted with dichloromethane (2 x 30 mL). The aqueous phases were combined and the pH was adjusted with aqueous hydrochloric acid (6N) to 2. The precipitated solid was collected by filtration and dried to give the title compound 1.28 g (69% yield) as a brown solid.1H NMR (400 MHz, CDCl3) δ: 12.86 (s, 1H), 10.50 (s, 1H), 7.55 (m, 1H), 7.32-7.30 (m. 2H), 3.56 (s, 2H).

References

[1] Patent: US2015/284327, 2015, A1. Location in patent: Paragraph 0215; 0216
[2] Patent: WO2006/64044, 2006, A1. Location in patent: Page/Page column 21-22

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Methyl 2-oxoindole-6-carboxylate 2,3-Dioxoindoline-6-carboxylic acid Sodium hydroxide Methanol

Preparation Products

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID Suppliers

Global( 118)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58

Supplier	Advantage
Accela ChemBio Inc.	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
career henan chemical co	58
Fuxin Pharmaceutical	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58

View Lastest Price from 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-06-02	6-carboxyoxindole ; 6-Carboxyl-2-oxindole; 2-Oxoindoline-6-carboxylic acid in stock Factory 334952-09-9	$1.00	1kg	2-Oxo-2,3-dihydro-1H-indole-6-carboxylic acid		Chemwill Asia Co.,Ltd.
	2020-01-05	2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID 334952-09-9	$1.00	1KG	99%	200kg	Career Henan Chemical Co

6-carboxyoxindole ; 6-Carboxyl-2-oxindole; 2-Oxoindoline-6-carboxylic acid in stock Factory
334952-09-9
$1.00
2-Oxo-2,3-dihydro-1H-indole-6-carboxylic acid
Chemwill Asia Co.,Ltd.

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID
334952-09-9
$1.00
99%
Career Henan Chemical Co

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID Spectrum

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID(334952-09-9)¹HNMR

334952-09-9(2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID)Related Search:

2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER 2-OXO-2,3-DIHYDRO-1H-INDOLE-5-CARBOXYLIC ACID METHYL ESTER N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide Methyl 1-acetyl-2-oxoindoline-6-carboxylate Oxindole

1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate 1-ACETYL-2-OXO-2,3-DIHYDRO-1H-INDOLE-5-CARBOXYLIC ACID METHYL ESTER 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER 1-Chloro-4-(trimethoxymethyl)benzene Nintedanib Impurity 76

ALPHA,ALPHA,2,4-TETRACHLOROTOLUENE N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate N-Methyl-4-nitroaniline 2-PROPANESULFONIC ACID SODIUM SALT MON&

Nintedanib Impurity 67 1,2-dichloro-4-(dichloromethyl)benzene BIBF 1202

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2-oxo-1,3-dihydroindole-6-carboxylic acid 2-Oxoindoline-6-carboxylic acid in stock Factory Nidanib Impurity 2: 2-oxy-2,3-dihydro-1H-indole-6-carboxylic acid RARECHEM AL BO 0984 OXINDOLE-6-CARBOXYLIC ACID 2,3-DIHYDRO-2-OXO-1H-INDOLE-6-CARBOXYLIC ACID 2-Oxindole-6-carboxylic acid 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID 6-OXINDOLECARBOXYLIC ACID 6-CARBOXYOXINDOLE 2-Oxo-indoline-6-carboxylic acid 2,3-Dihydro-2-oxo-1H-indole-6-carboxylic acid97% 1H-Indole-6-carboxylic acid, 2,3-dihydro-2-oxo- 6-Carboxyl-2-oxindole 2-Oxyindole-6-carboxylic acid Intedanib Impurity 30 334952-09-9 blocks Carboxes IndolesOxindoles pharmacetical Indoline & Oxindole