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ChemicalBook >> CAS DataBase List >>[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt)

[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt)

[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt) Structure
[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt) structure
CAS No.
Chemical Name:
[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt)
Synonyms
[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt)
CBNumber:
CB54665709
Molecular Formula:
C150H222F3N41O49S
Molecular Weight:
3472.6731896
MDL Number:
MOL File:
Mol file
Last updated:2025-08-21 11:10:20
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[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt) Properties

solubility Formic Acid: 1 mg/ml

[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt) price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24459 [Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt) ≥95% 1mg $388 2026-04-30 Buy
Product number Packaging Price Buy
24459 1mg $388 Buy

[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt) Chemical Properties, Uses, Production

Description

[Des-His1,Glu9]-Glucagon (1-29) amide is a peptide glucagon receptor antagonist (pA2 = 7.25 for glucagon binding to isolated rat liver membranes).1 It binds to glucagon receptors in a magnesium- and GTP-independent manner to stimulate breakdown of inositol phospholipids by phospholipase C, but has no effect on adenylate cyclase activity, in hepatocytes.1,2 In vivo, [Des-His1,Glu9]-glucagon (1-29) amide prevents glucagon-induced hyperglycemia in rabbits and decreases blood glucose in rats with diabetes induced by streptozotocin (Item No. 13104).1WARNING This product is not for human or veterinary use.

References

[1] CECILIA G. UNSON  R. B M  Ellen M Gurzenda. Biological activities of des-His1[Glu9]glucagon amide, a glucagon antagonist[J]. Peptides, 1989, 10 6: Pages 1171-1177. DOI: 10.1016/0196-9781(89)90010-7
[2] S R POST  H S T  P G Rubinstein. Mechanism of action of des-His1-[Glu9]glucagon amide, a peptide antagonist of the glucagon receptor system.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1993, 90 5: 1662-1666. DOI: 10.1073/pnas.90.5.1662

[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt) Preparation Products And Raw materials

Raw materials

Preparation Products

[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt) Suppliers

Global Suppliers ( 5)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58

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[Des-His1,Glu9]-Glucagon (1-29) amide (trifluoroacetate salt)