LIN-28B ANTIBODY
- CAS No.
- Chemical Name:
- LIN-28B ANTIBODY
- Synonyms
- LIN-28B ANTIBODY
- CBNumber:
- CB54728787
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
LIN-28B ANTIBODY price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb253708 | LIN28B Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb1841 | Lin 28B antibody Affinity purified by Protein A | 100μg | $421.6 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb1841 | Lin 28B antibody Affinity purified by Protein A | 200μg | $673.2 | 2021-12-16 | Buy |
LIN-28B ANTIBODY Chemical Properties, Uses, Production
Source
Rabbit
Reactivity
Human
Background
LIN28A and LIN28B are conserved, developmentally regulated RNA binding proteins that inhibit the processing and maturation of the let-7 family of miRNAs. The let-7 miRNAs have been implicated in repression of oncogenes such as Ras, Myc, and HMGA2. It has recently been shown that upregulation of LIN28A and LIN28B in primary human tumors and human cancer cell lines is correlated with downregulation of let-7 miRNAs. LIN28 genes are reported to be involved in primordial germ cell development and germ cell malignancy. In addition, allelic variation in LIN28B is associated with regulating the timing of puberty in humans. Overexpression of LIN28A, in conjunction with Oct-4, Sox2, and Nanog, can reprogram human fibroblasts to pluripotent, ES-like cells.
References
[1] Balzer, E. and Moss, E.G. (2007) RNA Biol 4, 16-25.
[2] Piskounova, E. et al. (2008) J Biol Chem 283, 21310-4.
[3] Cho, W.C. (2007) Mol Cancer 6, 60.
[4] Viswanathan, S.R. et al. (2009) Nat Genet 41, 843-8.
[5] West, J.A. et al. (2009) Nature 460, 909-13.
[6] Ong, K.K. et al. (2009) Nat Genet 41, 729-33.
[7] Yu, J. et al. (2007) Science 318, 1917-20.
LIN-28B ANTIBODY Preparation Products And Raw materials
Raw materials
Preparation Products
LIN-28B ANTIBODY Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Universal Biotech Co.,Ltd | 58 |
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
