Linzagolix
- CAS No.
- 935283-04-8
- Chemical Name:
- Linzagolix
- Synonyms
- OBE2109;RMA-895;OBE 2109;OBE-2109;Linzagolix;Linzagolix CAS;Zavegepant Impurity 55;Linzagolix, 10 mM in DMSO;3-{5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4-d]pyrimidine-5-carboxylic acid;3-(5-((2,3-difluoro-6-methoxybenzyl)oxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid
- CBNumber:
- CB54844986
- Molecular Formula:
- C22H15F3N2O7S
- Molecular Weight:
- 508.42
- MDL Number:
- MOL File:
- 935283-04-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Linzagolix ≥98% | 39654 | 1mg | $39 |
| Linzagolix ≥98% | 39654 | 5mg | $164 |
| Linzagolix ≥98% | 39654 | 10mg | $308 |
| Linzagolix ≥98% | 39654 | 25mg | $626 |
| Linzagolix 99.68% | CS-0039392 | 1mg | $49 |
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO : 125 mg/mL (245.86 mM; Need ultrasonic) |
| form | Solid |
| color | White to light brown |
| InChIKey | BMAAMIIYNNPHAB-UHFFFAOYSA-N |
| SMILES | C1(=O)N(C2=CC(OCC3=C(OC)C=CC(F)=C3F)=C(OC)C=C2F)C(=O)C2=C(C(O)=O)SC=C2N1 |
| FDA UNII | 7CDW97HUEX |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
Linzagolix price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 39654 | Linzagolix ≥98% | 935283-04-8 | 1mg | $39 | 2026-04-30 | Buy |
| Cayman Chemical | 39654 | Linzagolix ≥98% | 935283-04-8 | 5mg | $164 | 2026-04-30 | Buy |
| Cayman Chemical | 39654 | Linzagolix ≥98% | 935283-04-8 | 10mg | $308 | 2026-04-30 | Buy |
| Cayman Chemical | 39654 | Linzagolix ≥98% | 935283-04-8 | 25mg | $626 | 2026-04-30 | Buy |
| ChemScene | CS-0039392 | Linzagolix 99.68% | 935283-04-8 | 1mg | $49 | 2026-06-04 | Buy |
Linzagolix Chemical Properties,Uses,Production
Uses
Linzagolix (KLH-2109; OBE-2109) is a potent, non-peptide, and orally active GnRH antagonist. Linzagolix can be used for uterine fibroids, endometriosis, adenomyosis research[1][2][3].
in vivo
Linzagolix (50 mg/kg) reduces cyst volume in a rat model of endometriosis[1].
Lindagolix reduces serum luteinizing hormone and testosterone levels in male rats and dogs with normal or BPH models[2].
| Animal Model: | Endometriosis model rat[1] |
| Dosage: | 50 mg/kg |
| Administration: | |
| Result: | Reduced cyst volume. |
References
[1] Motohiro Tezuka, et al. Suppressive effects of linzagolix, a novel non-peptide antagonist of gonadotropin-releasing hormone receptors, in experimental endometriosis model rats. Clin Exp Pharmacol Physiol. 2023 Jul;50(7):610-617. DOI:10.1111/1440-1681.13778
[2] Motohiro Tezuka, et al. Suppression of hypothalamic-pituitary-gonadal function by linzagolix in benign prostatic hyperplasia and polycystic ovary syndrome animal models. Clin Exp Pharmacol Physiol. 2023 Nov;50(11):914-923. DOI:10.1111/1440-1681.13817
[3] Susan Dababou, et al. Linzagolix: a new GnRH-antagonist under investigation for the treatment of endometriosis and uterine myomas. Expert Opin Investig Drugs. 2021 Sep;30(9):903-911. DOI:10.1080/13543784.2021.1957830
Linzagolix Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Linzagolix Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 | sales@sdperfect.com | China | 294 | 58 |
| Moxin Chemicals | +86-17320513646 +8617320513646 | anna@molcoo.com | China | 10000 | 58 |
| Wuhan JiyunZen Tech Co., Ltd. | +86-18062099985 | Amyjiyunzen@yeah.net | China | 672 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Shenzhen Shengda Pharma Limited | 755-85269922 +8613424394241 | sales@shengdapharm.com | CHINA | 310 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| DEI MEI YI YAO KE JI LLC | +852-52854821 +852-52854821 | cici71684@gmail.com | China | 879 | 58 |
| TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD | +86-576-88902229;+86-0576-88902229 +8613968687450 | yuxin@yuxchem.com | China | 167 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Cangzhou Kangrui Pharma Tech Co. Ltd., | +86-18632776803 +86-13833998158 | cangzhoukangrui@126.com | China | 773 | 58 |
View Lastest Price from Linzagolix manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-10 | Linzagolix
935283-04-8
|
$2.00-5.00 | 1KG | 99% hplc | 500TONS | Wuhan JiyunZen Tech Co., Ltd. | |
 |
2026-03-27 | Linzagolix
935283-04-8
|
1g | 98% HPLC | 100kg | shandong perfect biotechnology co.ltd | ||
 |
2025-12-16 | Linzagolix
935283-04-8
|
10mg | 98 | 10000000 | Moxin Chemicals |
-
- Linzagolix
935283-04-8
- $2.00-5.00
- 99% hplc
- Wuhan JiyunZen Tech Co., Ltd.
-
- Linzagolix
935283-04-8
- $0.00
- 98% HPLC
- shandong perfect biotechnology co.ltd
-
- Linzagolix
935283-04-8
- 98
- Moxin Chemicals
