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t-Boc-N-amido-PEG1-NHS ester

CAS No.
1260092-55-4
Chemical Name:
t-Boc-N-amido-PEG1-NHS ester
Synonyms
Boc-N-PEG1-C2-NHS ester;BocNH-PEG1-CH2CH2COONHS;t-Boc-N-amido-PEG1-NHS ester;2,5-Dioxopyrrolidin-1-yl 3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate;Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester;BocNH-PEG1-CH2CH2COONHS/Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber:
CB54849668
Molecular Formula:
C14H22N2O7
Molecular Weight:
330.33
MDL Number:
MFCD20227793
MOL File:
1260092-55-4.mol
Last updated:2025-08-21 22:16:43

t-Boc-N-amido-PEG1-NHS ester Properties

Density 1.26±0.1 g/cm3(Predicted)
storage temp. Storage temp. -20°C
pka 12.21±0.46(Predicted)
form Solid
color White to off-white

t-Boc-N-amido-PEG1-NHS ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-23959 t-Boc-N-amido-PEG1-NHSester 98% 1260092-55-4 250mg $380 2021-12-16 Buy
BroadPharm BP-23959 t-Boc-N-amido-PEG1-NHSester 98% 1260092-55-4 500mg $580 2021-12-16 Buy
Activate Scientific AS107902 BocNH-PEG1-CH2CH2COONHS 97% 1260092-55-4 1g $580 2021-12-16 Buy
BroadPharm BP-23959 t-Boc-N-amido-PEG1-NHSester 98% 1260092-55-4 1g $870 2021-12-16 Buy
Ambeed A581867 2,5-Dioxopyrrolidin-1-yl3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate 98% 1260092-55-4 5g $645 2021-12-16 Buy
Product number Packaging Price Buy
BP-23959 250mg $380 Buy
BP-23959 500mg $580 Buy
AS107902 1g $580 Buy
BP-23959 1g $870 Buy
A581867 5g $645 Buy

t-Boc-N-amido-PEG1-NHS ester Chemical Properties,Uses,Production

Description

t-Boc-N-amido-PEG1-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-amido-PEG1-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

t-Boc-N-amido-PEG1-NHS ester Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32432 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39031 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 1924344760@confluore.cn China 2997 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Shanghai Raise Chemical Technology Co.,Ltd 15026594951 rs@raise-chem.com China 4251 55
Bide Pharmatech Ltd. 400-164-7117 13681763483 product02@bidepharm.com China 42446 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Amatek Scientific Co. Ltd. 0512-56316828 info@amateksci.com China 28785 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4952 58

View Lastest Price from t-Boc-N-amido-PEG1-NHS ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-N-PEG1-C2-NHS ester pictures 2025-08-21 Boc-N-PEG1-C2-NHS ester
1260092-55-4
US $0.00 / mg 10g TargetMol Chemicals Inc.
t-Boc-N-amido-PEG1-NHS ester pictures 2025-06-07 t-Boc-N-amido-PEG1-NHS ester
1260092-55-4
US $0.00 / g 5g >98.00% 5g Xian confluore Biological Technology Co., Ltd.

t-Boc-N-amido-PEG1-NHS ester Spectrum

t-Boc-N-amido-PEG1-NHS ester BocNH-PEG1-CH2CH2COONHS Boc-N-PEG1-C2-NHS ester 2,5-Dioxopyrrolidin-1-yl 3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate BocNH-PEG1-CH2CH2COONHS/Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester 1260092-55-4