ETHYL 6-HYDROXY-2-NAPHTHOATE
- CAS No.
- 17295-12-4
- Chemical Name:
- ETHYL 6-HYDROXY-2-NAPHTHOATE
- Synonyms
- Naproxen Impurity 51;Ethyl6-hydroxy-2-naphtoate;ETHYL 6-HYDROXY-2-NAPHTHOATE;6-hydroxy-2-naphthoic acid ethyl ester;ethyl 6-hydroxynaphthalene-2-carboxylate;2-Naphthalenecarboxylic acid, 6-hydroxy-, ethyl ester
- CBNumber:
- CB5501764
- Molecular Formula:
- C13H12O3
- Molecular Weight:
- 216.23
- MDL Number:
- MFCD07368972
- MOL File:
- 17295-12-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl6-hydroxy-2-naphthoate | 8922AA | 1g | $138 |
| Ethyl 6-hydroxy-2-naphthoate 97% | 083671 | 1g | $360 |
| ETHYL-6-HYDROXY-2-NAPHTHOATE 98.00% | CHM0166310 | 5MG | $501.57 |
| Ethyl6-naphthol-2-carboxylate | 17295124 | 500mg | $1019.2 |
| Ethyl6-naphthol-2-carboxylate | 17295124 | 1g | $1685 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
ETHYL 6-HYDROXY-2-NAPHTHOATE price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 8922AA | Ethyl6-hydroxy-2-naphthoate | 17295-12-4 | 1g | $138 | 2021-12-16 | Buy |
| Matrix Scientific | 083671 | Ethyl 6-hydroxy-2-naphthoate 97% | 17295-12-4 | 1g | $360 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0166310 | ETHYL-6-HYDROXY-2-NAPHTHOATE 98.00% | 17295-12-4 | 5MG | $501.57 | 2021-12-16 | Buy |
| Alichem | 17295124 | Ethyl6-naphthol-2-carboxylate | 17295-12-4 | 500mg | $1019.2 | 2021-12-16 | Buy |
| Alichem | 17295124 | Ethyl6-naphthol-2-carboxylate | 17295-12-4 | 1g | $1685 | 2021-12-16 | Buy |
ETHYL 6-HYDROXY-2-NAPHTHOATE Chemical Properties,Uses,Production
Synthesis
64-17-5
16712-64-4
17295-12-4
1. 6-Hydroxy-2-naphthalenecarboxylic acid (5.29 g, 28.0 mmol) was dissolved in ethanol (50 mL) at 0 °C, and thionyl chloride (6 mL) was added slowly. 2. The reaction mixture was stirred at room temperature for 72 h. 3. Upon completion of the reaction, the excess reagent was removed by rotary evaporation. 4. The residue was dissolved in ethyl acetate (100 mL), and washed with water (80 mL), cold 1M sodium bicarbonate solution (80 mL) and brine (80 mL). 5. （The residue was dissolved in ethyl acetate (100 mL) and washed sequentially with water (80 mL), cold 1 M sodium bicarbonate solution (80 mL) and brine (80 mL). 5. The organic phase was dried over anhydrous sodium sulfate, filtered, and concentrated to give ethyl 6-hydroxy-2-naphthoate in 99% yield. 6. The product was characterized by 1H NMR (CDCl3) and LCMS (APCl): 1H NMR (CDCl3): δ 8.53 (1H, br s), 8.5 (1H, br s), 8.3 (1H, br s), 8.4 (1H, br s). , br s), 8.01 (1H, dd, J = 8.5,1.7 Hz), 7.86 (1H, d, J = 8.5 Hz), 7.20-7.13 (2H, m), 4.43 (2H, q, J = 7.3 Hz), 1.43 (3H, t, J = 7.1 Hz). lcmS (apcl): 217.1 (m + h + ).
References
[1] Patent: WO2006/40646, 2006, A1. Location in patent: Page/Page column 97
[2] Journal of Physical Chemistry A, 2016, vol. 120, # 33, p. 6563 - 6574
[3] Journal of Medicinal Chemistry, 2004, vol. 47, # 14, p. 3518 - 3536
[4] Molecular Crystals and Liquid Crystals, 2008, vol. 494, p. 282 - 292
[5] Tetrahedron, 2013, vol. 69, # 43, p. 9045 - 9055
ETHYL 6-HYDROXY-2-NAPHTHOATE Preparation Products And Raw materials
ETHYL 6-HYDROXY-2-NAPHTHOATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30228 | 58 |
| Shandong Liteng Biotechnology Co. , Ltd. | +86-18663721413 +86-15552573001 | rosy@litengpharm.com | China | 3282 | 58 |
| QUALITY CONTROL SOLUTIONS LTD. | +86-0755-66853366 +86-13670046396 | export03@qcsrm.com | China | 24342 | 58 |
| Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. | 21-57721279 18121011378 | sales@shydchem.com.cn | China | 998 | 56 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | chenyj@titansci.com | China | 14101 | 59 |
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 998 | 60 |
| SynAsst Chemical. | 021-60343070 | China | 12740 | 55 | |
| Chengdu Research Accelerators Technology Co., Ltd. | 028-64353063 | reacchemical@163.com | China | 5253 | 58 |
