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Schisandrin A

CAS No.
61281-38-7
Chemical Name:
Schisandrin A
Synonyms
WUWEIZISU A;SCHIZANDRIN A;SCHISANDRIN A;Doxyschizandrin;DEOXYSCHISANDRIN;DEOXYSCHIZANDRIN;Schizandrin A-RM;DiMethylgoMisin J;R(+) SCHISANDRIN A;R(+) SCHIZANDRIN A
CBNumber:
CB5670585
Molecular Formula:
C24H32O6
Molecular Weight:
416.51
MDL Number:
MFCD00221760
MOL File:
61281-38-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:02
Product description Number Pack Size Price
Schisandrin A ≥98% (HPLC) SMB00368 10mg $125
Schisandrin A analytical standard 90139 50mg $390
Schisandrin A C3501 25MG $87
Schisandrin A C3501 100MG $241
Schisandrin A ≥98% 19849 5mg $43

Schisandrin A Properties

Melting point 116-117 °C
Boiling point 544.2±50.0 °C(Predicted)
Density 1.080±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form powder
color White to Off-White
Major Application metabolomics
vitamins, nutraceuticals, and natural products
InChI 1S/C24H32O6/c1-13-9-15-11-17(25-3)21(27-5)23(29-7)19(15)20-16(10-14(13)2)12-18(26-4)22(28-6)24(20)30-8/h11-14H,9-10H2,1-8H3/t13-,14+
InChIKey JEJFTTRHGBKKEI-OKILXGFUSA-N
SMILES C[C@@H](C1)[C@H](C)CC2=C(C3=C1C=C(OC)C(OC)=C3OC)C(OC)=C(OC)C(OC)=C2
LogP 5.870 (est)
FDA UNII 74XQL5DO3S
UNSPSC Code 41116107
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
RTECS  HP1595000
HS Code  29093090
Storage Class 11 - Combustible Solids

Schisandrin A price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SMB00368 Schisandrin A ≥98% (HPLC) 61281-38-7 10mg $125 2026-03-19 Buy
Sigma-Aldrich 90139 Schisandrin A analytical standard 61281-38-7 50mg $390 2022-05-15 Buy
TCI Chemical C3501 Schisandrin A 61281-38-7 25MG $87 2026-03-19 Buy
TCI Chemical C3501 Schisandrin A 61281-38-7 100MG $241 2026-03-19 Buy
Cayman Chemical 19849 Schisandrin A ≥98% 61281-38-7 5mg $43 2023-06-20 Buy
Product number Packaging Price Buy
SMB00368 10mg $125 Buy
90139 50mg $390 Buy
C3501 25MG $87 Buy
C3501 100MG $241 Buy
19849 5mg $43 Buy

Schisandrin A Chemical Properties,Uses,Production

Description

Schisandrin A is a lignan that has been found in Schisandra and has diverse biological activities. It binds to adiponectin receptor 2 (IC50 = 3.2 μM). Schisandrin A (10, 20, and 50 μM) reduces LPS-induced production of nitric oxide (NO), IL-6, and TNF-α and apoptosis in primary mouse microglial cells. It reverses P-glycoprotein-mediated doxorubicin resistance in MCF-7/dox cells when used at a concentration of 20 μM. Schisandrin A (4, 12, and 36 mg/kg) reverses short-term and spatial memory deficits, as well as decreases in cerebral superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities induced by amyloid β (1-42) (Aβ42; ) in a mouse model of Alzheimer’s disease.

Chemical Properties

White powder

Uses

Schizandrin A is an extract from Schisandra chinesis. a dibenzocyclooctadiene lignan with antiinflammatory activity.

in vivo

Schisandrin A (SchA) significantly inhibits CYP3A activity in rat hepatic microsomes and Vmax value of each group in a concentration-dependent manner. The double-reciprocal plots and the secondary plot show that Schisandrin A inhibits CYP3A activity, with an apparent Ki value of 30.67 mg/kg. In each Schisandrin A-treated group, Schisandrin A also significantly decreases 1-hydroxymidazolam plasma concentrations compared with the negative group (to levels similar to the positive group)[2].

IC 50

CYP3A: 6.6 μM (IC50); Autophagy

References

[1] YIYI SUN. Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay.[J]. PLoS ONE, 2013: e63354. DOI: 10.1371/journal.pone.0063354
[2] FANG-JIAO SONG. Schizandrin A Inhibits Microglia-Mediated Neuroninflammation through Inhibiting TRAF6-NF-κB and Jak2-Stat3 Signaling Pathways[J]. PLoS ONE, 2016, 11 1. DOI: 10.1371/journal.pone.0149991
[3] ZONG-LIN ZHANG  Su R W  Qing Cheng Jiang. Schisandrin A reverses doxorubicin-resistant human breast cancer cell line by the inhibition of P65 and Stat3 phosphorylation.[J]. Breast Cancer, 2018, 25 2: 233-242. DOI: 10.1007/s12282-017-0821-9
[4] DI HU. Deoxyschizandrin isolated from the fruits of Schisandra chinensis ameliorates Aβ-induced memory impairment in mice.[J]. Planta medica, 2012, 78 12: 1332-1336. DOI: 10.1055/s-0032-1315019

Schisandrin A Preparation Products And Raw materials

Raw materials

Preparation Products

Schisandrin A Suppliers

Global( 142)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15003564040 1056@dideu.com China 3982 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Alfa Chemistry
+1-5166625404; Info@alfa-chemistry.com United States 20405 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618829768577 gao490372054@gamil.com China 1249 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 43333 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501 product@acmec-e.com China 33324 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618791163155 18791163155@163.com China 3397 58

View Lastest Price from Schisandrin A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Schisandrin A pictures 2026-02-02 Schisandrin A
61281-38-7
US $0.10-10.00 / KG 0.10000000149011612KG 98% 200TONS Shaanxi Dideu Medichem Co. Ltd
  • Schisandrin A pictures
  • Schisandrin A
    61281-38-7
  • US $0.10-10.00 / KG
  • 98%
  • Shaanxi Dideu Medichem Co. Ltd

Schisandrin A Spectrum

SCHISANDRIN A (DEOXYSCHISANDRIN) SCHISANDRA CHINENSIS PLANT EXTRACT 9+% SCHISANDRINS SCHISANDRA CHINENSIS PLANT EXTRACT 5+% SCHISANDRINS SCHISANDRA PLANT EXTRACT SCHISANDRA BERRY POWDER SCHISANDRIN A, (DEOXYSCHISANDRIN) 98% BY HPLC SCHISANDRA CHINENSIS PLANT EXTRACT 2+% SCHISANDRINS DEOXYSCHIZANDRIN90%,99% SCHISANDRIN A(DEOXYSCHISANDRIN) SNAPN 0.1mg/ml(SH) SCHISANDRIN A(DEOXYSCHISANDRIN)(P) dibenzo(a,c)cyclooctene,5,6,7,8-tetrahydro-6,7-dimethyl-1,2,3,10,11,12-hexamet R(+) DEOXYSCHISANDRIN A R(+) DEOXYSCHIZANDRIN A R(+) SCHISANDRIN A R(+) SCHIZANDRIN A SCHIZANDRIN A SCHISANDRIN A WUWEIZISU A DEOXYSCHISANDRIN DEOXYSCHIZANDRIN (+)-Deoxyschisandrin 1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-,(6R,7S,12aR)- Dibenzo [a,c]cyclooctene,5,6,7,8-tetrahydro- Schisandrin A,Schizandrin A,(+)-Deoxyschisandrin,Deoxyschizandrin (+)-Deoxyschisandrin,Deoxyschizandrin DEOXYSCHIZANDRIN SCHISANDRIN A Deoxyschizandrin, 98%, from magnoliavine P.E Schisandrin A(Deoxyschizandrin) DiMethylgoMisin J Deoxyschizandrin, froM Magnoliavine P.E Doxyschizandrin Schizandrin A (+)-Deoxyschisandrin,Deoxyschizandrin Deoxyschizandrin, 98%, from Schisandra chinensis (Turcz.) Baill. Dibenzo[a,c]cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, (6R,7S,12aR)- (6R,7S,12aR)-5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene Inhibitor,Schisandrin A,Cytochrome P450,Schizandrin-A,Autophagy,Deoxyschizandrin,Virus Protease,inhibit,Wuweizisu-A,Schizandrin A,CYPs Schizandrin A-RM Schizandrin A, 10 mM in DMSO Compound T2926(SC) 61281-38-7 Miscellaneous Natural Products Inhibitors chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract