Schisandrin A
- CAS No.
- 61281-38-7
- Chemical Name:
- Schisandrin A
- Synonyms
- WUWEIZISU A;SCHIZANDRIN A;SCHISANDRIN A;Doxyschizandrin;DEOXYSCHISANDRIN;DEOXYSCHIZANDRIN;Schizandrin A-RM;DiMethylgoMisin J;R(+) SCHISANDRIN A;R(+) SCHIZANDRIN A
- CBNumber:
- CB5670585
- Molecular Formula:
- C24H32O6
- Molecular Weight:
- 416.51
- MDL Number:
- MFCD00221760
- MOL File:
- 61281-38-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Schisandrin A ≥98% (HPLC) | SMB00368 | 10mg | $125 |
| Schisandrin A analytical standard | 90139 | 50mg | $390 |
| Schisandrin A | C3501 | 25MG | $87 |
| Schisandrin A | C3501 | 100MG | $241 |
| Schisandrin A ≥98% | 19849 | 5mg | $43 |
| Melting point | 116-117 °C |
|---|---|
| Boiling point | 544.2±50.0 °C(Predicted) |
| Density | 1.080±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | powder |
| color | White to Off-White |
| Major Application |
metabolomics vitamins, nutraceuticals, and natural products |
| InChI | 1S/C24H32O6/c1-13-9-15-11-17(25-3)21(27-5)23(29-7)19(15)20-16(10-14(13)2)12-18(26-4)22(28-6)24(20)30-8/h11-14H,9-10H2,1-8H3/t13-,14+ |
| InChIKey | JEJFTTRHGBKKEI-OKILXGFUSA-N |
| SMILES | C[C@@H](C1)[C@H](C)CC2=C(C3=C1C=C(OC)C(OC)=C3OC)C(OC)=C(OC)C(OC)=C2 |
| LogP | 5.870 (est) |
| FDA UNII | 74XQL5DO3S |
| UNSPSC Code | 41116107 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | HP1595000 |
| HS Code | 29093090 |
| Storage Class | 11 - Combustible Solids |
Schisandrin A price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00368 | Schisandrin A ≥98% (HPLC) | 61281-38-7 | 10mg | $125 | 2026-03-19 | Buy |
| Sigma-Aldrich | 90139 | Schisandrin A analytical standard | 61281-38-7 | 50mg | $390 | 2022-05-15 | Buy |
| TCI Chemical | C3501 | Schisandrin A | 61281-38-7 | 25MG | $87 | 2026-03-19 | Buy |
| TCI Chemical | C3501 | Schisandrin A | 61281-38-7 | 100MG | $241 | 2026-03-19 | Buy |
| Cayman Chemical | 19849 | Schisandrin A ≥98% | 61281-38-7 | 5mg | $43 | 2023-06-20 | Buy |
Schisandrin A Chemical Properties,Uses,Production
Description
Schisandrin A is a lignan that has been found in Schisandra and has diverse biological activities. It binds to adiponectin receptor 2 (IC50 = 3.2 μM). Schisandrin A (10, 20, and 50 μM) reduces LPS-induced production of nitric oxide (NO), IL-6, and TNF-α and apoptosis in primary mouse microglial cells. It reverses P-glycoprotein-mediated doxorubicin resistance in MCF-7/dox cells when used at a concentration of 20 μM. Schisandrin A (4, 12, and 36 mg/kg) reverses short-term and spatial memory deficits, as well as decreases in cerebral superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities induced by amyloid β (1-42) (Aβ42; ) in a mouse model of Alzheimer’s disease.
Chemical Properties
White powder
Uses
Schizandrin A is an extract from Schisandra chinesis. a dibenzocyclooctadiene lignan with antiinflammatory activity.
in vivo
Schisandrin A (SchA) significantly inhibits CYP3A activity in rat hepatic microsomes and Vmax value of each group in a concentration-dependent manner. The double-reciprocal plots and the secondary plot show that Schisandrin A inhibits CYP3A activity, with an apparent Ki value of 30.67 mg/kg. In each Schisandrin A-treated group, Schisandrin A also significantly decreases 1-hydroxymidazolam plasma concentrations compared with the negative group (to levels similar to the positive group)[2].
IC 50
CYP3A: 6.6 μM (IC50); Autophagy
References
[1] YIYI SUN. Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay.[J]. PLoS ONE, 2013: e63354. DOI: 10.1371/journal.pone.0063354
[2] FANG-JIAO SONG. Schizandrin A Inhibits Microglia-Mediated Neuroninflammation through Inhibiting TRAF6-NF-κB and Jak2-Stat3 Signaling Pathways[J]. PLoS ONE, 2016, 11 1. DOI: 10.1371/journal.pone.0149991
[3] ZONG-LIN ZHANG Su R W Qing Cheng Jiang. Schisandrin A reverses doxorubicin-resistant human breast cancer cell line by the inhibition of P65 and Stat3 phosphorylation.[J]. Breast Cancer, 2018, 25 2: 233-242. DOI: 10.1007/s12282-017-0821-9
[4] DI HU. Deoxyschizandrin isolated from the fruits of Schisandra chinensis ameliorates Aβ-induced memory impairment in mice.[J]. Planta medica, 2012, 78 12: 1332-1336. DOI: 10.1055/s-0032-1315019
Schisandrin A Preparation Products And Raw materials
Raw materials
Preparation Products
Schisandrin A Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3982 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 | gao490372054@gamil.com | China | 1249 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618791163155 | 18791163155@163.com | China | 3397 | 58 |
View Lastest Price from Schisandrin A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-02-02 | Schisandrin A
61281-38-7
|
US $0.10-10.00 / KG | 0.10000000149011612KG | 98% | 200TONS | Shaanxi Dideu Medichem Co. Ltd |
-

- Schisandrin A
61281-38-7
- US $0.10-10.00 / KG
- 98%
- Shaanxi Dideu Medichem Co. Ltd
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