2-(Allyloxy)phenol
- CAS No.
- 1126-20-1
- Chemical Name:
- 2-(Allyloxy)phenol
- Synonyms
- o-(allyloxy)phenol;2-(ALLYLOXY)-PHENOL;2-prop-2-enoxyphenol;2-(2-Propenyloxy)phenol;Phenol, 2-(2-propenyloxy)-;Allyl(o-hydroxyphenyl) ether;Phenol, 2-(2-propen-1-yloxy)-;Oxprenolol 2-Allyloxyphenol Impurity;2-Allyloxyphenol,97%(stabilized with MEHQ)
- CBNumber:
- CB5683701
- Molecular Formula:
- C9H10O2
- Molecular Weight:
- 150.17
- MDL Number:
- MFCD00072617
- MOL File:
- 1126-20-1.mol
- MSDS File:
- SDS
| Melting point | 30.2 °C |
|---|---|
| Boiling point | 110 °C(Press: 12 Torr) |
| Density | 1.091 g/cm3(Temp: 15 °C) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Dichloromethane |
| form | Oil |
| pka | 9.72±0.35(Predicted) |
| color | Pale Yellow |
| InChI | InChI=1S/C9H10O2/c1-2-7-11-9-6-4-3-5-8(9)10/h2-6,10H,1,7H2 |
| InChIKey | FNEJKCGACRPXBT-UHFFFAOYSA-N |
| SMILES | C1(O)=CC=CC=C1OCC=C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2909500090 |
2-(Allyloxy)phenol price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR950199 | 2-(Allyloxy)phenol >96% | 1126-20-1 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR950199 | 2-(Allyloxy)phenol >96% | 1126-20-1 | 5g | $69 | 2026-06-04 | Buy |
| Apolloscientific | OR950199 | 2-(Allyloxy)phenol >96% | 1126-20-1 | 25g | $331 | 2026-06-04 | Buy |
| Apolloscientific | OR950199 | 2-(Allyloxy)phenol >96% | 1126-20-1 | 100g | $1312 | 2026-06-04 | Buy |
| Activate Scientific | AS46734 | 2-(Allyloxy)phenol 97% | 1126-20-1 | 5g | $184 | 2026-06-04 | Buy |
2-(Allyloxy)phenol Chemical Properties, Uses, Production
Chemical Properties
Pale Yellow Oil
Uses
2-Allyloxyphenol, isolated from marine actinobacterium, possesses strong antioxidant property and has inhibitory effect towards some bacteria and fungi when applied at concentraions of 0.2-1.75 mg/mL. Used in the preparation of Oxprenolol (O870500), a β-Adrenergic blocker.
Synthesis
120-80-9
106-95-6
1126-20-1
Step 1) Preparation of compound B: Compound B: 2-(allyloxy)phenol Anhydrous potassium carbonate (K2CO3) (6.36 g, 0.046 mol) (6.36 g, 0.046 mol) was added to an anhydrous acetone (20 mL) solution of catechol (Compound A) (5 g, 0.045 mol) in batches over 30 minutes. The reaction mixture was stirred at room temperature for 1 hour. Subsequently, 3-bromo-1-propene (3.84 mL, 0.045 mol) was added slowly and dropwise to the above mixture over 30 minutes. The reaction mixture was heated to 60-70 °C and refluxed for 5 hours. After completion of the reaction, the K2CO3 was removed by filtration. the filtrate was concentrated, extracted with chloroform (3 x 75 mL), the organic phases were combined and washed with brine (1 x 50 mL) and dried with anhydrous sodium sulfate. The crude product was purified by silica gel column chromatography (silica gel; 60-120 mesh) with the eluent being a gradient increasing solvent mixture of chloroform/petroleum ether. The petroleum ether eluate containing 4% chloroform was collected and concentrated to give pure compound B as a viscous orange liquid. Yield: 5.8 g (85%). 1H NMR (300MHz, CDCl3): δ 4.59 (d, J=4.29Hz, 2H), 5.35 (qt, J=17.2,10.46Hz, 2H), 5.69 (s, 1H), 6.04-6.08 (m, 1H), 6.81-6.96 (m, 4H). Mass spectrum (ESI) m/z: 149 [M-H]-.
References
[1] Patent: WO2010/79423, 2010, A1. Location in patent: Page/Page column 19-20
[2] Patent: US2014/135393, 2014, A1. Location in patent: Paragraph 0170-0174
[3] Helvetica Chimica Acta, 2006, vol. 89, # 3, p. 416 - 426
[4] Tetrahedron Letters, 2004, vol. 45, # 12, p. 2631 - 2633
[5] Tetrahedron, 1996, vol. 52, # 17, p. 6187 - 6200
2-(Allyloxy)phenol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Run-Biotech Co., Ltd. | 021-57171705 13817537615 | sales@run-biotech.com | China | 2277 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 94607 | 76 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 qq272369594;2159423853qq | 2723695949@qq.com | China | 4990 | 50 |
| Shanghai Changyan Chem & Tech Co., Ltd. | 021-20242659 18930833303 | sales@changyanchem.cn | China | 4998 | 55 |
| Changzhou PBpharmaceutical R&D Co.,Ltd | 086-0519-83990708 18915800124 | info@pbpharm.com | China | 480 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Latest Price from 2-(Allyloxy)phenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 2-(Allyloxy)phenol
1126-20-1
|
1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2021-07-02 | 2-Allyloxyphenol
1126-20-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2020-02-02 | 2-(Allyloxy)phenol
1126-20-1
|
$1.00 | 1KG | 97% | 200kg | Career Henan Chemical Co |
-
- 2-(Allyloxy)phenol
1126-20-1
- $0.10
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Allyloxyphenol
1126-20-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 2-(Allyloxy)phenol
1126-20-1
- $1.00
- 97%
- Career Henan Chemical Co
