Methyl (R)-(+)-lactate
- CAS No.
- 17392-83-5
- Chemical Name:
- Methyl (R)-(+)-lactate
- Synonyms
- Methyl (R)-2-Hydroxypropanoate;METHYL-(R)-LACTATE;D-Methyl Lactate;D-LACTIC ACID METHYL ESTER;DLAM;D- METHYL D-LACTATE;Methyl-(R)-lactat;METHYL D-(+)-LACTATE;(+)-Methyl D-lactate
- CBNumber:
- CB5694817
- Molecular Formula:
- C4H8O3
- Molecular Weight:
- 104.1
- MDL Number:
- MFCD00004517
- MOL File:
- 17392-83-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (+)-Methyl D-lactate 98%, optical purity ee: 96% (GLC) | 277762 | 5g | $146 |
| Methyl D-(+)-Lactate >98.0%(GC) | L0136 | 5g | $42 |
| Methyl D-(+)-Lactate >98.0%(GC) | L0136 | 25g | $134 |
| D-Methyl lactate | 281843 | 50g | $322 |
| Methyl D-(+)-Lactate | M315230 | 100g | $625 |
| More product size | |||
| alpha | 8.5 º (c=neat) |
|---|---|
| Boiling point | 144-145 °C(lit.) |
| Density | 1.09 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 121 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | 13.07±0.20(Predicted) |
| form | Liquid |
| color | Clear colorless |
| optical activity | [α]21/D +8.4°, neat |
| Water Solubility | miscible, hydrolyses |
| Merck | 14,6094 |
| InChI | 1S/C4H8O3/c1-3(5)4(6)7-2/h3,5H,1-2H3/t3-/m1/s1 |
| InChIKey | LPEKGGXMPWTOCB-GSVOUGTGSA-N |
| SMILES | COC(=O)[C@@H](C)O |
| LogP | -0.719 (est) |
| CAS DataBase Reference | 17392-83-5(CAS DataBase Reference) |
| FDA UNII | 45MZ1T3TBV |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H319-H335 | |||||||||
| Precautionary statements | P210-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 10-36/37 | |||||||||
| Safety Statements | 16-24-24/25 | |||||||||
| RIDADR | UN 3272 3/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29181100 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 3 STOT SE 3 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
Methyl (R)-(+)-lactate price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 277762 | (+)-Methyl D-lactate 98%, optical purity ee: 96% (GLC) | 17392-83-5 | 5g | $146 | 2026-03-19 | Buy |
| TCI Chemical | L0136 | Methyl D-(+)-Lactate >98.0%(GC) | 17392-83-5 | 5g | $42 | 2026-03-19 | Buy |
| TCI Chemical | L0136 | Methyl D-(+)-Lactate >98.0%(GC) | 17392-83-5 | 25g | $134 | 2026-03-19 | Buy |
| Usbiological | 281843 | D-Methyl lactate | 17392-83-5 | 50g | $322 | 2021-12-16 | Buy |
| TRC | M315230 | Methyl D-(+)-Lactate | 17392-83-5 | 100g | $625 | 2021-12-16 | Buy |
Methyl (R)-(+)-lactate Chemical Properties,Uses,Production
Chemical Properties
Colorless to light yellow liqui
Uses
(+)-Methyl D-lactate can be used as a starting material in the asymmetric preparation of:
- Neomethymycin, a macrolide which contains 12-membered macrolactone that is used as a potent biological agent.
- PM-toxin A.
It can also be used as a chiral pool along with D-(-)-tartaric acid in the stereoselective total synthesis of separacenes A and B via Trost-Rychnovsky alkyne rearrangement, Horner-Wadsworth-Emmons olefination as well as Corey-Bakshi-Shibata reaction.
Definition
ChEBI: A methyl lactate that has R configuration.
General Description
This compound has benign qualities and is biodegradable, water miscible, and functions as a versatile solvent for CA membrane preparation. This is also used as an intermediate for the production of other chemicals, polymers, and derivatives. Thus this product has been enhanced for Safer solvents and auxiliaries.
Synthesis
547-64-8
79-33-4
17392-83-5
The general procedure for the synthesis of L-lactic acid and D-lactic acid methyl ester from methyl lactate was as follows: in a standard 500-μL hydrolysis reaction system, 140 μg of purified esterase PHE14, 50 mmol/L of racemic methyl lactate as substrate, and 50 mmol/L of phosphate buffer (pH 7.5) were added. The reaction system was incubated at 37°C for 1 hour. Upon completion of the reaction, the reaction samples were extracted using an equal volume of ethyl acetate, and the organic phase was subsequently analyzed to assess the enzymatic disassembly of (±)-lactic acid methyl ester.
References
[1] Chinese Journal of Catalysis, 2016, vol. 37, # 8, p. 1396 - 1402
[2] Green Chemistry, 2013, vol. 15, # 10, p. 2817 - 2824
Methyl (R)-(+)-lactate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong Chem-land Co.,Ltd. | +undefined13862903883 | sales@chem-land.com | China | 61 | 58 |
| Henan Xiangduo Industry Co., Ltd. | +86-15981848961 +86-15981848961; | sales@xiangduochem.com | China | 497 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 | bj1@bj-chem.com | China | 299 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21592 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
View Lastest Price from Methyl (R)-(+)-lactate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Methyl (R)-(+)-lactate
17392-83-5
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-04-22 | Methyl (R)-(+)-lactate
17392-83-5
|
US $0.00 / KG | 1KG | 98.0% | 5000kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-03-20 | Methyl (R)-(+)-lactate
17392-83-5
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Methyl (R)-(+)-lactate
17392-83-5
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Methyl (R)-(+)-lactate
17392-83-5
- US $0.00 / KG
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Methyl (R)-(+)-lactate
17392-83-5
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
