Hydroxylamine-O-sulfonic acid
- CAS No.
- 2950-43-8
- Chemical Name:
- Hydroxylamine-O-sulfonic acid
- Synonyms
- HOSA;HYDROXYLAMINE-O-SULPHONIC ACID;HOS;amino hydrogen sulfate;HydroxylaMine-0-sulfonic acid;HYDROXYLAMINESULFONIC ACID;haos;Amino hydrogen sulphate;o-hydroxylammoniumsulfonate;TBX5
- CBNumber:
- CB5702901
- Molecular Formula:
- H3NO4S
- Molecular Weight:
- 113.09
- MDL Number:
- MFCD00011604
- MOL File:
- 2950-43-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Anti-FBXW11 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | HPA072204 | 100μL | $667 |
| Anti-FBXW11 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | HPA062578 | 100μL | $667 |
| Hydroxylamine-O-sulfonic acid 97% | 213136 | 25g | $163 |
| Anti-FBXW11 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | HPA072204 | 25μL | $282 |
| Hydroxylamine-O-sulfonic Acid >90.0%(T) | H0530 | 25g | $76 |
| More product size | |||
| Melting point | 210 °C (dec.)(lit.) |
|---|---|
| Boiling point | 39 °C(Press: 0.4 Torr) |
| Density | 2.2 g/cm3 (20℃) |
| vapor pressure | 0-53.329Pa at 25-39℃ |
| storage temp. | 2-8°C |
| solubility | 675g/l (slow decomposition) |
| pka | -6.47±0.18(Predicted) |
| form | Crystalline Powder |
| color | White |
| PH | 0.8 (100g/l, H2O, 20℃) |
| biological source | rabbit |
| Water Solubility | soluble |
| Sensitive | Hygroscopic |
| BRN | 956566 |
| InChI | 1S/H3NO4S/c1-5-6(2,3)4/h1H2,(H,2,3,4) |
| InChIKey | DQPBABKTKYNPMH-UHFFFAOYSA-N |
| SMILES | NOS(O)(=O)=O |
| CAS DataBase Reference | 2950-43-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| EPA Substance Registry System | Hydroxylamine-O-sulfonic acid (2950-43-8) |
| UNSPSC Code | 12352300 |
| NACRES | NA.43 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314-H410 | |||||||||
| Precautionary statements | P260-P280-P301+P312+P330-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C,N | |||||||||
| Risk Statements | 34-50-43-40-22 | |||||||||
| Safety Statements | 26-36/37/39-45-61-28A-27-22 | |||||||||
| RIDADR | UN 3260 8/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NC5427000 | |||||||||
| F | 10-21 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 28111980 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 3 Eye Dam. 1 Skin Corr. 1B |
|||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
Hydroxylamine-O-sulfonic acid price More Price(79)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA072204 | Anti-FBXW11 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | 100μL | $667 | 2026-04-30 | Buy | |
| Sigma-Aldrich | HPA062578 | Anti-FBXW11 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | 100μL | $667 | 2026-04-30 | Buy | |
| Sigma-Aldrich | 213136 | Hydroxylamine-O-sulfonic acid 97% | 2950-43-8 | 25g | $163 | 2026-04-30 | Buy |
| Sigma-Aldrich | HPA072204 | Anti-FBXW11 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | 25μL | $282 | 2023-06-20 | Buy | |
| TCI Chemical | H0530 | Hydroxylamine-O-sulfonic Acid >90.0%(T) | 2950-43-8 | 25g | $76 | 2026-04-30 | Buy |
Hydroxylamine-O-sulfonic acid Chemical Properties,Uses,Production
Chemical Properties
white to slightly beige crystalline powder
Uses
Hydroxylamine-O-sulfonic acid is used in the synthesis of quinolones for the benzodiazepine site of GABAA receptors. It is also used as a polymerization catalyst and an amination reagent. It is involved in the preparation of diazene by reacting with an alkali. It is also used in the inhibition of polychlorinated dibenzo-p-dioxins (PCDD) as well as (polychlorinated biphenyl) PCB formation in co-combustion.
Uses
Hydroxylamine-O-sulfonic acid (HOSA) may be used to synthesize (Z)-1H-purin-6(7H)-ylideneaminooxysulfonic acid.
HOSA may be used as an aminating reagent in the synthesis of:
- 1-aminotetrazoles and 2-aminotetrazoles
- N-aminopiperidine (NAPP)
- 1H,1′ H-2,2′-biimidazole-1,1′-diamine
General Description
Hydroxylamine-O-sulfonic acid is a versatile synthetic reagent. It is widely employed as a nucleophile and as an electrophile in various organic syntheses. It can be synthesized by reacting hydroxylamine sulfate with 30% fuming H2SO4.
Synthesis
63 ml of 20~25% fuming sulfuric acid was slowly added dropwise to 16.4 g of hydroxylamine sulfate under mechanical stirring. The temperature was controlled below 60°C, and the time of dropwise addition was 40~60 minutes. After the dropwise addition, the temperature was raised to 60°C and the reaction was continued with stirring for 2~3 hours. Cool to 10°C and stir for 1 hour, then drop 100ml of ethyl acetate. The concentrated solution was allowed to stand for half an hour, separated and rapidly filtered. The crude product was washed with ethyl acetate and dried under vacuum to yield 21.5 g of hydroxylamine-O-sulfonic acid (95% yield). The product was stored on P2O6 in a vacuum desiccator. The purity of the product was 87.69%.
Purification Methods
Stir the solid vigorously with anhydrous Et2O and filter it off using large volumes of dry Et2O. Drain dry at the pump for 5minutes and then for 12-14hours in a vacuum. Store it in a vacuum desiccator over conc H2SO4. Determine the purity by oxidation of iodide to I2. It must be stored in a dry atmosphere at 0-4o. It decomposes slowly in H2O at 25o and more rapidly above this temperature. [Matsuguma & Andrieth Inorg Synth V 122 1957.]
Hydroxylamine-O-sulfonic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 | bj1@bj-chem.com | China | 299 | 55 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14014 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
View Lastest Price from Hydroxylamine-O-sulfonic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-28 | Hydroxylamine-O-sulfonic acid
2950-43-8
|
$9.00 | 1KG | 99.8% | 100tons | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-03-20 | Hydroxylamine-O-sulfonic acid
2950-43-8
|
$9.90 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2024-08-05 | Hydroxylamine-O-sulfonic acid
2950-43-8
|
1kg | 99% | 5MT | Shanghai Bojing Chemical Co.,Ltd. |
-
- Hydroxylamine-O-sulfonic acid
2950-43-8
- $9.00
- 99.8%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Hydroxylamine-O-sulfonic acid
2950-43-8
- $9.90
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Hydroxylamine-O-sulfonic acid
2950-43-8
- 99%
- Shanghai Bojing Chemical Co.,Ltd.
