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Travoprost

Travoprost Structure
Travoprost structure
CAS No.
157283-68-6
Chemical Name:
Travoprost
Synonyms
Trovoprost;Trivo;FLU-IPR;AL 6221;Travatan;ravopros;Trivoprost;Travaprost;TRAVOPROST;Travoprostt
CBNumber:
CB5703458
Molecular Formula:
C26H35F3O6
Molecular Weight:
500.55
MDL Number:
MFCD03411995
MOL File:
157283-68-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
Travoprost Pharmaceutical Secondary Standard; Certified Reference Material PHR1622 3mL $201
Fluprostenol isopropyl ester ≥98%, ethanol solution F2427 1 mg $178
Travoprost 1673001 3ml $479
Travoprost T4329 100MG $321
Fluprostenol isopropyl ester ≥98% 16769 1mg $77
More product size
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Travoprost Properties

alpha D20 +14.6° (c = 1.0 in methylene chloride)
Boiling point 584.8±50.0 °C(Predicted)
Density 1.245±0.06 g/cm3(Predicted)
Flash point 17 °C
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Dichloromethane (Sparingly, Sonicated), Chloroform (Sparingy), Methanol (Sparing
pka 13.43±0.20(Predicted)
form ethanol solution
color Colourless to Light Beige
BCS Class 2
Stability Light Sensitive
InChIKey MKPLKVHSHYCHOC-AHTXBMBWSA-N
SMILES C(OC(C)C)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)COC1=CC=CC(C(F)(F)F)=C1
CAS DataBase Reference 157283-68-6(CAS DataBase Reference)
FDA UNII WJ68R08KX9
ATC code S01EE04
UNSPSC Code 41116107
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P305+P351+P338
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  16-26-36-7
RIDADR  UN 1170 3/PG 2
WGK Germany  1
HS Code  2937500000
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 2
NFPA 704
0
2 0

Travoprost price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1622 Travoprost Pharmaceutical Secondary Standard; Certified Reference Material 157283-68-6 3mL $201 2026-04-30 Buy
Sigma-Aldrich F2427 Fluprostenol isopropyl ester ≥98%, ethanol solution 157283-68-6 1 mg $178 2026-04-30 Buy
Sigma-Aldrich 1673001 Travoprost 157283-68-6 3ml $479 2026-04-30 Buy
TCI Chemical T4329 Travoprost 157283-68-6 100MG $321 2026-04-30 Buy
Cayman Chemical 16769 Fluprostenol isopropyl ester ≥98% 157283-68-6 1mg $77 2026-04-30 Buy
Product number Packaging Price Buy
PHR1622 3mL $201 Buy
F2427 1 mg $178 Buy
1673001 3ml $479 Buy
T4329 100MG $321 Buy
16769 1mg $77 Buy

Travoprost Chemical Properties,Uses,Production

Description

Travoprost was launched in the US as Travatan, an ophthalmic solution (0.004%) administered topically for the treatment of elevated intraocular hypertension (lOP) through open-angle glaucoma, a common optic neuropathy and a leading cause of blindness. Travoprost is the isopropyl ester of (+)-fluprostenol, a new prostaglandin derivative belonging to the PGF2α, analog class. This compound can be prepared in 8 steps from a bicyclic lactone aldehyde by a Wittig alkylidenation followed, after 2 ketonic reductions, by a lactol opening to prostenoic acid while protecting and deprotecting appropriately. Travoprost is a full agonist of FP receptors with a greater affinity than PGF2α, (K1 = 52 nM). Pharmacologic studies in rabbits treated daily for a week demonstrated a significant increase of the microvascular optic nerve head blood flow without significant alterations in the systemic flow. In several placebo-controlled clinical studies with hundreds of patients suffering from open-angle glaucoma or ocular hypertension, travoprost (1 to 4 pm daily) dose-dependently reduced lOP (by about 30% at 4 pm); it was shown equal or superior to latanoprost, another prostaglandin analog (5 pm daily) or the adrenergic ~-blocker timolol (500 pm bid). In addition, travoprost was safe and well tolerated with a low incidence of conjunctival hyperaemia.

Chemical Properties

Colorless Oil

Originator

Alcon (US)

Uses

Travoprost is a selective FP prostaglandin receptor agonist used to treat glaucoma (1,2).

Uses

Selective FP prostaglandin receptor agonist. Isopropyl ester of (+)-fluprostenol. Antiglaucoma

Uses

treatment conditions arising from excess uric acid, eg chronic gout

Definition

ChEBI: The isopropyl ester of prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophth lmic solutions of travoprost are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. It is a pro-drug; the isopropyl ester group is hydrolysed by esterases in the co nea to the biologically active free acid, fluprostenol.

brand name

Travatan

General Description

Travoprost (Travatan and Travatan-Z) is supplied asa 2.5- or 5.0-mL sterile 0.004% ophthalmic solution in a4.0- or 7.5-mL size container. Travoprost is claimed to bethe most potent and FP-specific analog in this product category. Cautions and side effects are similar to those givenpreviously.

Travoprost Preparation Products And Raw materials

Raw materials

Preparation Products

Travoprost Suppliers

Global( 437)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Quanjinci New Material Co.,Ltd. 		+86-15271838296; +8615271838296 kyra@quanjinci.com China 1512 58
airuikechemical co., ltd. 		+86-18353166132 sales02@airuikechemical.com China 983 58
Wuhan JiyunZen Tech Co., Ltd. 		+86-18062099985 Amyjiyunzen@yeah.net China 672 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13843 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
Shanghai finete Pharmaceutical Co., Ltd. 		+86-18221039705 CHINA 139 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29819 58
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338 stella@zetchem.com China 2994 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Supplier Advantage
Wuhan Quanjinci New Material Co.,Ltd. 		58
airuikechemical co., ltd. 		58
Wuhan JiyunZen Tech Co., Ltd. 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai finete Pharmaceutical Co., Ltd. 		55
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Xiamen AmoyChem Co., Ltd 		58
Standardpharm Co. Ltd. 		58

View Lastest Price from Travoprost manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Travoprost pictures 2026-05-05 Travoprost
157283-68-6
 0.99 RongNa Biotechnology Co.,Ltd
Travoprost pictures 2026-04-30 Travoprost
157283-68-6
 US $0.00 / g 1g 96%-102% 100G WUHAN FORTUNA CHEMICAL CO., LTD
Travoprost pictures 2026-04-29 Travoprost
157283-68-6
 US $0.00 / Kg/Bag 2Kg/Bag USP32 20 tons Sinoway Industrial co., ltd.
  • Travoprost pictures
  • Travoprost
    157283-68-6
  • 0.99
  • RongNa Biotechnology Co.,Ltd
  • Travoprost pictures
  • Travoprost
    157283-68-6
  • US $0.00 / g
  • 96%-102%
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Travoprost pictures
  • Travoprost
    157283-68-6
  • US $0.00 / Kg/Bag
  • USP32
  • Sinoway Industrial co., ltd.

Travoprost Spectrum

Travoprost(157283-68-6)1HNMR

157283-68-6(Travoprost)Related Search:

Anisole Glycolic acid CHLOROPHOSPHONAZO III (Trifluoromethoxy)benzene Methylparaben
Prostaglandin E2 Hydroxy silicone oil Epoprostenol Propane HYDROXYAPATITE TYPE I
4-Hydroxybenzaldehyde Prostaglandin E1 Bimatoprost Latanoprost (+)-Fluprostenol
9-KETO FLUPROSTENOL 9-keto Fluprostenol isopropyl ester 15-Keto Travoprost

1of4

(+)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methyethyl ester (+/-)-16-(M-TRIFLUOROMETHYLPHENOXY)TETRANORPROSTAGLANDIN F2 15(S)-FLU-IPR 15(S)-FLUPROSTENOL ISOPROPYL ESTER 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)- trevostaglandin Travoprost Eye Drops Travoprost（Fluprostenol Isopropyl Ester） propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate Trivo Trivoprost 9ALPHA,11ALPHA,15S-TRIHYDROXY-16(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER (+)-FLUPROSTENOL ISOPROPYL ESTER FLUPROSTENOL ISOPROPYL ESTER FLU-IPR propan-2-yl (e)-7-[(1r,2s,3r,5s)-3,5-dihydroxy-2-[(e)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester AL 6221 Travaprost Travatan TRAVOPROST propan-2-yl 7-[(1R,2S,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate Travoprost (For eye drops) cGMP Travoprost propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoroMethyl)phenoxy]but-1-en-1-yl]cyclopentyl]hept-5-enoate (4-isopropyloxcarbonylbutyl)dipenhylphosphine oxide Travoprost, (±)-16-(m-Trifluoromethylphenoxy)tetranorprostaglandin F2 Travoprostintermediates Travoprost (AL-6221) (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]buten-1-yl][cyclopentyl]hept-5-enoate Travoprost, >=99% Travoprost Impurity 33 Travoprost USP/EP/BP Trovoprost isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate Travoprostum (Z)-Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate Travoprost D7 TravoprostQ: What is Travoprost Q: What is the CAS Number of Travoprost Q: What is the storage condition of Travoprost Q: What are the applications of Travoprost Travoprost (COLD SHIPMENT REQUIRED) (1673001) ravopros Travoprostt Travoprost API Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R,E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoate 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-(5Z)-5-heptenoic acid 1-methylethyl ester Travoprost, 10 mM in DMSO Quvoprost/Quvoprost (5Z)-isopropyl 7-((1R,2R,3R,5S)-2-((R,E)-4-(3-(trifluoromethyl)phenoxy)-3-hydroxybut-1-enyl)-3,5-dihydroxycyclopentyl)hept-5-enoate 157283-68-6 157283-62-7 C26H35F3O6 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals Prostaglandins Prostaglandin