4-Formyl-N,N-dimethyl-benzamide
- CAS No.
- 58287-76-6
- Chemical Name:
- 4-Formyl-N,N-dimethyl-benzamide
- Synonyms
- 130912;4-Formyl-N,N-dimethyl-benzamide;Benzamide, 4-formyl-N,N-dimethyl-;4-(N,N-DIMETHYLCARBAMOYL)BENZALDEHYDE
- CBNumber:
- CB5749997
- Molecular Formula:
- C10H11NO2
- Molecular Weight:
- 177.2
- MDL Number:
- MFCD07186279
- MOL File:
- Mol file
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
4-Formyl-N,N-dimethyl-benzamide price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | ICA28776 | 4-Formyl-N,N-dimethyl-benzamide | 58287-76-6 | 0.5g | $359.9 | 2026-06-04 | Buy |
| Biosynth | ICA28776 | 4-Formyl-N,N-dimethyl-benzamide | 58287-76-6 | 5g | $1239 | 2026-06-04 | Buy |
| Activate Scientific | AS187321 | 4-Formyl-N,N-dimethylbenzamide 95% | 58287-76-6 | 250mg | $232 | 2026-06-04 | Buy |
| Activate Scientific | AS187321 | 4-Formyl-N,N-dimethylbenzamide 95% | 58287-76-6 | 1g | $450 | 2026-06-04 | Buy |
| A1 Biochem Labs | A1-03514 | 4-Formyl-N,N-dimethyl-benzamide 0.95 | 58287-76-6 | 1g | $175 | 2026-06-05 | Buy |
4-Formyl-N,N-dimethyl-benzamide Chemical Properties, Uses, Production
Synthesis
619-66-9
68-12-2
58287-76-6
Example 101 Synthesis of 4-formyl-N,N-dimethylbenzamide: To an anhydrous dichloromethane (8 mL) suspension of 4-formylbenzoic acid (4.00 g, 26.7 mmol), thionyl chloride (2.92 g, 40.0 mmol) and N,N-dimethylformamide (0.6 mL) were added sequentially. The reaction was carried out dropwise at room temperature under nitrogen protection. Subsequently, the reaction mixture was heated to reflux for 2 hours. Upon completion of the reaction, it was cooled to room temperature and then slowly added dropwise to 33% aqueous dimethylamine solution (10.5 mL, 72 mmol) in an ice-water bath for 15 minutes. After the dropwise addition, the reaction mixture was continued to be stirred at the same temperature for 1 hour. At the end of the reaction, the solvent was removed by distillation under reduced pressure. The crude product was purified by silica gel column chromatography to afford the title compound (2.5 g, 53% yield) as a yellow solid. ^1H-NMR (400 MHz, DMSO-d6) δ (ppm): 2.86 (s, 3H), 3.30 (s, 3H), 7.60 (d, J = 7.6 Hz, 2H), 7.95 (d, J = 7.6 Hz, 2H), 10.04 (s, 1H); LC-MS (ESI) m/z: 178 (M + 1)+.
References
[1] Patent: WO2011/130661, 2011, A1. Location in patent: Page/Page column 153
4-Formyl-N,N-dimethyl-benzamide Preparation Products And Raw materials
Raw materials
Preparation Products
4-Formyl-N,N-dimethyl-benzamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Zhixin Biomedical Technology Co., Ltd. | 15366165407 | 33192244545@qq.com | China | 445 | 58 |
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