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Sesamin

Sesamin structure

CAS No.: 607-80-7

Chemical Name:: Sesamin

Synonyms: L-Sesamin;FAGAROL;SesameP.E.;SezaMin;SESAMIN;Fsesamin;d-Sesamin;NSC 36403;AI3-00811;SESAMIN(P)

CBNumber:: CB5783674

Molecular Formula:: C20H18O6

Molecular Weight:: 354.35

MDL Number:: MFCD00216134

MOL File:: 607-80-7.mol

MSDS File:: SDS

Last updated:2025-10-17 11:55:56

Product description	Number	Pack Size	Price
Sesamin ≥98% (HPLC)	SMB00705	10MG	$234
Sesamin ≥98% (HPLC)	SMB00705	50MG	$863
Sesamin analytical standard	59867	10mg	$236
Sesamin ≥95%, crystalline	S9314	5mg	$436
Sesamin >98.0%(GC)	S0495	100mg	$362
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Sesamin Properties

Melting point	121.0 to 125.0 °C
Boiling point	504.4±50.0 °C(Predicted)
Density	1.385±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO (>25 mg/ml)
form	crystalline
color	White
biological source	Sesamum indicum (sesame)
Merck	14,8470
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI	InChI=1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2
InChIKey	PEYUIKBAABKQKQ-AFHBHXEDSA-N
SMILES	O1CC2C(C3=CC=C4OCOC4=C3)OCC2C1C1=CC=C2OCOC2=C1
LogP	4.064 (est)
FDA UNII	S7946O4P76
UNSPSC Code	85151701
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H317

Precautionary statements

P261-P272-P280-P302+P352-P333+P313-P362+P364

Safety Statements

22-24/25

WGK Germany

HS Code

29329990

NFPA 704

	1
0		0

Sesamin price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SMB00705	Sesamin ≥98% (HPLC)	607-80-7	10MG	$234	2025-07-31	Buy
Sigma-Aldrich	SMB00705	Sesamin ≥98% (HPLC)	607-80-7	50MG	$863	2025-07-31	Buy
Sigma-Aldrich	59867	Sesamin analytical standard	607-80-7	10mg	$236	2025-07-31	Buy
Sigma-Aldrich	S9314	Sesamin ≥95%, crystalline	607-80-7	5mg	$436	2022-05-15	Buy
TCI Chemical	S0495	Sesamin >98.0%(GC)	607-80-7	100mg	$362	2025-07-31	Buy

Product number	Packaging	Price	Buy
SMB00705	10MG	$234	Buy
SMB00705	50MG	$863	Buy
59867	10mg	$236	Buy
S9314	5mg	$436	Buy
S0495	100mg	$362	Buy

Sesamin Chemical Properties,Uses,Production

Description

Sesamin (607-80-7) is a natural product derived from sesame seeds with anticancer1, antioxidant2, anti-inflammatory/immunomodulatory3, and antidiabetic4,5 effects. It also displayed effects on cholesterol and fatty acid metabolism.6? Sesamin was recently found to inhibit bacterial L-tryptophan indole lyase (Ki = 7 μM).7 This enzyme reacts with dietary tryptophan to produce the uremic toxin indoxyl sulfate which exacerbates chronic kidney disease.

Chemical Properties

White powder

Uses

A lignan isolated from the bark of Fagara plants and from sesame oil. Studies show that it has has multiple functions such as cholesterol-lowering and anti-hypertensive activities. It induces the expr ession of the gene for aldehyde dehydrogenase, an alcohol-metabolizing enzyme suggesting it regulates the metabolism of lipids, xenobiotics, and alcohol at the mRNA level.

Uses

Sesamin has been used:

as a lignan to study its effects on the osteoblastic differentiation of rat bone marrow stromal cells (BMSCs)
as a standard for the isolation of sesamin from sesame oil
as an enterolignan to study its effects on the proliferation of estrogen-receptor (ER)-positive human breast cancer MCF-7 cells

Definition

ChEBI: A lignan that consists of tetrahydro-1H,3H-furo[3,4-c]furan substituted by 1,3-benzodioxole groups at positions 1 and 4 (the 1S,3aR,4S,6aR

General Description

Sesamin is a fat-soluble furfuran lignan present in Sesamum indicum?L seeds.

Biochem/physiol Actions

Non-competitive Δ5-desaturase inhibitor.

References

[1] AMIN F. MAJDALAWIEH Gheyath K N Mariam Massri. A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum)[J]. European journal of pharmacology, 2017, 815: Pages 512-521. DOI:10.1016/j.ejphar.2017.10.020
[2] KISO Y. Antioxidative roles of sesamin, a functional lignan in sesame seed, and it’s effect on lipid- and alcohol-metabolism in the liver: A DNA microarray study[J]. BioFactors, 2008, 21 1-4: 191-196. DOI:10.1002/biof.552210139
[3] AMIN F MAJDALAWIEH. Immunomodulatory and anti-inflammatory effects of sesamin: mechanisms of action and future directions.[J]. Critical reviews in food science and nutrition, 2022, 62 18: 5081-5112. DOI:10.1080/10408398.2021.1881438
[4] MAJID MOHAMMAD SHAHI. Effect of Sesamin Supplementation on Glycemic Status, Inflammatory Markers, and Adiponectin Levels in Patients with Type 2 Diabetes Mellitus.[J]. Journal of Dietary Supplements, 2017, 14 1: 65-75. DOI:10.1080/19390211.2016.1204404
[5] YAGHOOB FARBOOD . Sesamin: A promising protective agent against diabetes-associated cognitive decline in rats[J]. Life sciences, 2019, 230: Pages 169-177. DOI:10.1016/j.lfs.2019.05.071
[6] AMIN F. MAJDALAWIEH Sarah M Y Sarah Dalibalta. Effects of sesamin on fatty acid and cholesterol metabolism, macrophage cholesterol homeostasis and serum lipid profile: A comprehensive review[J]. European journal of pharmacology, 2020, 885: Article 173417. DOI:10.1016/j.ejphar.2020.173417
[7] DAIKI OIKAWA . (+)-Sesamin, a sesame lignan, is a potent inhibitor of gut bacterial tryptophan indole-lyase that is a key enzyme in chronic kidney disease pathogenesis[J]. Biochemical and biophysical research communications, 2022, 590: Pages 158-162. DOI:10.1016/j.bbrc.2021.12.088

Sesamin Preparation Products And Raw materials

Raw materials

Preparation Products

Sesamin Suppliers

Global( 475)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan Zhuoyu Yantang Technology Co., Ltd.	+8613288715578	sales@sichuanzyyt.com	China	12247	58
Shaanxi Xianhe Biotech Co., Ltd	+86-17709210191; +8617709210191	Jerry@xhobio.com	China	883	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Lianyungang Kaiyu Environmental Tech Co., Ltd.	+86-0086-19851820538 +8619851820538	carlos@khonorchem.com	China	262	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Shaanxi Yikanglong Biotechnology Co., Ltd.	17791478691	yklbiotech@163.com	CHINA	296	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	3751	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	1169	58

Supplier	Advantage
Sichuan Zhuoyu Yantang Technology Co., Ltd.	58
Shaanxi Xianhe Biotech Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Lianyungang Kaiyu Environmental Tech Co., Ltd.	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Shaanxi Yikanglong Biotechnology Co., Ltd.	58
Chengdu Biopurify Phytochemicals Ltd.	58
Xi'an Kono chem co., Ltd.,	58

View Lastest Price from Sesamin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-17	Sesamin 607-80-7	US $37.00-68.00 / mg		99.38%	10g	TargetMol Chemicals Inc.
2025-10-17	Sesamin 607-80-7	US $1200.00-1100.00 / ton	1ton	99%	1000T/M	Lianyungang Kaiyu Environmental Tech Co., Ltd.
2025-10-17	Sesamin 607-80-7	US $0.00 / kg	1kg	0.99	1000kg	Shaanxi Xianhe Biotech Co., Ltd

Sesamin
607-80-7
US $37.00-68.00 / mg
99.38%
TargetMol Chemicals Inc.

Sesamin
607-80-7
US $1200.00-1100.00 / ton
99%
Lianyungang Kaiyu Environmental Tech Co., Ltd.

Sesamin
607-80-7
US $0.00 / kg
0.99
Shaanxi Xianhe Biotech Co., Ltd

Sesamin Spectrum

Sesamin(607-80-7)MS Sesamin(607-80-7)¹HNMR Sesamin(607-80-7)IR1 Sesamin(607-80-7)IR2

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Rotundine pseudoprototimosaponin AIII Spirostan-3-ol

1of4

[1S-(1BETA,3ALPHA-BETA,4BETA,6ALPHA-BETA)]-5,5'-(TETRAHYDRO-1H,3H-FURO[3,4-C]FURAN-1,4-DIYL)BIS-1,3-BENZODIOXOLE SesameP.E. Sesamine70% SESAMIN(P) SESAMIN(RG) 1,3-Benzodioxole,5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-,[1S-(1α,3aα,4α, 6aα)]- 1,3-Benzodioxole, 5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-, [1S-(1a,3aa,4a,6aa)]- Tetrahydro-1,4-bis[3,4-(methylenedioxy)phenyl]-1H,3H-furo[3,4-c]furan (+)-5,5'-[(1S,3aβ,4S,6aβ)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]-bis-1,3-benzodioxole (+)-5,5'-[(1S,3aβ,4β,6aβ)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(1,3-benzodioxole) d-Sesamin Pseudocubebin SesaMin(Fagarol) NSC 36403 SezaMin (1S,3aR,4S,6aR)-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole 3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-ol (1S,3aR,4S,6aR)-Tetrahydro-1,4-bis[3,4-(Methylenedioxy)phenyl]-1H,3H-Furo[3,4-c]furan [1S-(1α,3aα,4α,6aα)]-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole SESAMIN FAGAROL SesaMin, froM SesaMuM indicuM 1,3-Benzodioxole,5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-, (1S,3aR,4S,6aR)- Fsesamin L-Sesamin Sesamin, >=98% Sesamin, 98%, from Sesamum indicum Sesamin> Sesamin USP/EP/BP Jujube powder Sesame Extract, Sesamin 5-[(3S,3aR,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole (1S,3aR,4S,6aR)-1,4-Bis(benzo[d][1,3]dioxol-5-yl)hexahydrofuro[3,4-c]furan Sesamin (Fagarol, Fsesamin) Sesamin, ≥95% TIANFU-CHEM -Sesamin (+)-sesamin Sesamin powder Sesame Extract (Sesamin 90%) Natural Sesamin Powder AI3-00811 Sesamin-RM Abametapir Impurity 28 Sesamin CRS 607-80-7 C20H15O5 C20H18O6 BioChemical Biochemicals and Reagents D to K Enzyme Inhibitors by Enzyme Enzyme Inhibitors Enzymes, Inhibitors, and Substrates D5-Desaturase Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals