Brolucizumab
- CAS No.
- 1531589-13-5
- Chemical Name:
- Brolucizumab
- Synonyms
- Brolucizumab;Brolucizumab (anti-VEGFA);Research Grade Brolucizumab;Research Grade Brolucizumab (DHD12603)
- CBNumber:
- CB58080928
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Brolucizumab 99.90% | CS-0147016 | 1mg | $1062 |
| Brolucizumab 99.90% | CS-0147016 | 5mg | $2974 |
| Brolucizumab 99.90% | CS-0147016 | 1mg | $1062 |
| Brolucizumab 99.90% | CS-0147016 | 5mg | $2974 |
| Brolucizumab 99.90% | HY-P9973 | 1mg | $931 |
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | XSZ53G39H5 |
| ATC code | S01LA06 |
Brolucizumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0147016 | Brolucizumab 99.90% | 1531589-13-5 | 1mg | $1062 | 2026-06-04 | Buy |
| ChemScene | CS-0147016 | Brolucizumab 99.90% | 1531589-13-5 | 5mg | $2974 | 2026-06-04 | Buy |
| ChemScene | CS-0147016 | Brolucizumab 99.90% | 1531589-13-5 | 1mg | $1062 | 2026-06-04 | Buy |
| ChemScene | CS-0147016 | Brolucizumab 99.90% | 1531589-13-5 | 5mg | $2974 | 2026-06-04 | Buy |
| Arctom | HY-P9973 | Brolucizumab 99.90% | 1531589-13-5 | 1mg | $931 | 2026-05-26 | Buy |
Brolucizumab Chemical Properties,Uses,Production
Uses
Brolucizumab (DLX1008) is a single-chain anti-VEGF-A antibody fragment with low picomolar affinity (KD=1.05 pM). Brolucizumab can be used for the research of cancer[1][2].
in vivo
Brolucizumab (15 mg/kg; i.p. 5 days per week for 21 or 41 days) slows the growth of mSLK-KSHV xenograft tumors[2].
Brolucizumab (5-50 mg/kg; i.p. once or twice daily for 28 days) delays in vivo tumor growth in U87MG glioma models[1].
Brolucizumab (10 mg/kg; i.v.) shows a half-life of 5.4-7.8 minutes for the rapid decline phase and 1.4-1.9 hours for the slow decline phase in mice[2].
| Animal Model: | NSG mice were subcutaneously injected with mSLK-KSHV cell suspension[2] |
| Dosage: | 15 mg/kg |
| Administration: | I.p. 5 days per week for 21 or 41 days |
| Result: | Significantly lowed tumor growth there was no difference in survival between experimental and combined control groups. |
References
[1] Szabó E, et, al. Antitumor Activity of DLX1008, an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity, in Human Glioma Models. J Pharmacol Exp Ther. 2018 May;365(2):422-429. DOI:10.1124/jpet.117.246249
[2] Eason AB, et, al. DLX1008 (brolucizumab), a single-chain anti-VEGF-A antibody fragment with low picomolar affinity, leads to tumor involution in an in vivo model of Kaposi Sarcoma. PLoS One. 2020 May 14;15(5):e0233116. DOI:10.1371/journal.pone.0233116
Brolucizumab Preparation Products And Raw materials
Raw materials
Preparation Products
Brolucizumab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19956 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 89686 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10308 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24955 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9865 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 7085 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11972 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4591 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | 6206333 13167063860 | anhua.mao@aladdin-e.com | China | 49997 | 58 |
View Lastest Price from Brolucizumab manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Brolucizumab
1531589-13-5
|
$813.00-2270.00 | 95.00% | 10g | TargetMol Chemicals Inc. |
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- Brolucizumab
1531589-13-5
- $813.00-2270.00
- 95.00%
- TargetMol Chemicals Inc.
