Fomc-Gly-Gly-Phe-Gly-OH
- CAS No.
- 1817857-75-2
- Chemical Name:
- Fomc-Gly-Gly-Phe-Gly-OH
- Synonyms
- Fmoc-GGFG;Fmoc-GGFG-OH;Fomc-Gly-Gly-Phe-Gly;Fomc-Gly-Gly-Phe-Gly-OH;(((9H-Fluoren-9-yl)methoxy)carbonyl)glycylglycyl-L-phenylalanylglycine;Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-L-phenylalanyl-;(S)-2-[2-[2-[2-(Fmoc-amino)acetamido]acetamido]-3-phenylpropanamido]acetic Acid;2-[[(2S)-2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid
- CBNumber:
- CB58110012
- Molecular Formula:
- C30H30N4O7
- Molecular Weight:
- 558.58
- MDL Number:
- MOL File:
- 1817857-75-2.mol
| Boiling point | 980.0±65.0 °C(Predicted) |
|---|---|
| Density | 1.329±0.06 g/cm3(Predicted) |
| storage temp. | -80°C, 2 years; -20°C, 1 year (Sealed storage, away from moisture) |
| pka | 3.32±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| Sequence | Fomc-Gly-Gly-Phe-Gly |
| InChIKey | LCOCGQVZUSLQJD-VWLOTQADSA-N |
| SMILES | C(O)(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Fomc-Gly-Gly-Phe-Gly-OH Chemical Properties,Uses,Production
Uses
Fomc-Gly-Gly-Phe-Gly-OH, also known as FMOC-GGFG-OH or 2-[[(2S)-2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid, can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit
Definition
Fomc-gly-gly-ph-gly-OH contains several functional groups. The Fmoc group is a commonly used protective group in peptide synthesis and is often used to protect N-terminal amino groups. Gly-Gly-Phe-Gly is glycyl-glycyl-phenylalanyl-glycine (GGFG) peptide which can be linked to other groups (drug) through cysteine residues. This tetrapeptide linker is protease-cleavable.
Fomc-Gly-Gly-Phe-Gly-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Fomc-Gly-Gly-Phe-Gly-OH Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xilinglab Co., Ltd. | +8618381337976 | bd@xilinglab.com | China | 86 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16517 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62320 | 58 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | sales@accelachem.com | China | 11040 | 64 |
| Tianjin Chempharmatech Co.,Ltd. | 022-66211079 13212288319 | sales@chempharmatech.com | China | 916 | 55 |
| Hygeia (Chengdu) pharmaceutical technique Co., Ltd | 028-84502008 13568869383 | sales@hygeiapharm.com | China | 300 | 55 |
