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3-Chloro-4-methylaniline

3-Chloro-4-methylaniline Structure
3-Chloro-4-methylaniline structure
CAS No.
95-74-9
Chemical Name:
3-Chloro-4-methylaniline
Synonyms
CPT;2-CHLORO-4-TOLUIDINE;4-amino-2-chlorotoluene[qr];3-CHLORO-4-METHYL-PHENYLAMINE;OCPT;3-cpt;cpt[qr];drc1347;2B oil;DKC 1347
CBNumber:
CB5854707
Molecular Formula:
C7H8ClN
Molecular Weight:
141.6
MDL Number:
MFCD00007773
MOL File:
95-74-9.mol
MSDS File:
SDS
Last updated:2026-05-28 01:22:50
Product description Number Pack Size Price
2-Chloro-4-aminotoluene 98% 236322 50g $50.5
3-Chloro-4-methylaniline >97.0%(GC) C0538 25g $102
3-Chloro-4-methylaniline >97.0%(GC) C0538 500g $617
3-​Chloro-​4-​methylaniline TRC-C587865-50G 50g $65
3-​Chloro-​4-​methylaniline TRC-C587865-500G 500g $271
More product size
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3-Chloro-4-methylaniline Properties

Melting point 25 °C
Boiling point 237-238 °C(lit.)
Density 1.17
vapor pressure 4.973-8.666Pa at 25℃
refractive index n20/D 1.584(lit.)
Flash point 212 °F
storage temp. 2-8°C
solubility Chloroform, Methanol (Slightly)
pka pK1: 4.05(+1) (25°C)
form powder to lump to clear liquid
color White or Colorless to Light orange to Yellow
Specific Gravity 1.167
Water Solubility 1 g/L (20 ºC)
BRN 636511
Henry's Law Constant 4.9×100 mol/(m3Pa) at 25℃, HSDB (2015)
Stability Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acids, acid anhydrides, chloroformates, reducing agents.
InChI 1S/C7H8ClN/c1-5-2-3-6(9)4-7(5)8/h2-4H,9H2,1H3
InChIKey RQKFYFNZSHWXAW-UHFFFAOYSA-N
SMILES Cc1ccc(N)cc1Cl
LogP 2.27
Toxicology and Carcinogenesis Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity (CASRN 95-74-9)
CAS DataBase Reference 95-74-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 32Y306W7BQ
NIST Chemistry Reference Benzenamine, 3-chloro-4-methyl-(95-74-9)
Pesticides Freedom of Information Act (FOIA) Starlicide,3-Chloro-4-methylbenzenamine
EPA Substance Registry System 3-Chloro-4-methylaniline (95-74-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Environment (GHS09)
GHS06,GHS09
Signal word  Danger
Hazard statements  H301+H311-H315-H317-H319-H410
Precautionary statements  P273-P280-P301+P310+P330-P302+P352+P312-P305+P351+P338
PPE Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes  T,N,Xn
Risk Statements  24/25-36/38-43-50/53-36/37/38-22
Safety Statements  36/37/39-45-61-60-36/37-26
RIDADR  UN 2239 6.1/PG 3
WGK Germany  2
RTECS  XU5111000
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  III
HS Code  29214300
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
Hazardous Substances Data 95-74-9(Hazardous Substances Data)
REACH Registrations Active
NFPA 704
1
3 0

3-Chloro-4-methylaniline price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 236322 2-Chloro-4-aminotoluene 98% 95-74-9 50g $50.5 2026-04-30 Buy
TCI Chemical C0538 3-Chloro-4-methylaniline >97.0%(GC) 95-74-9 25g $102 2026-04-30 Buy
TCI Chemical C0538 3-Chloro-4-methylaniline >97.0%(GC) 95-74-9 500g $617 2026-04-30 Buy
TRC TRC-C587865-50G 3-​Chloro-​4-​methylaniline 95-74-9 50g $65 2026-06-03 Buy
TRC TRC-C587865-500G 3-​Chloro-​4-​methylaniline 95-74-9 500g $271 2026-06-03 Buy
Product number Packaging Price Buy
236322 50g $50.5 Buy
C0538 25g $102 Buy
C0538 500g $617 Buy
TRC-C587865-50G 50g $65 Buy
TRC-C587865-500G 500g $271 Buy

3-Chloro-4-methylaniline Chemical Properties,Uses,Production

Chemical Properties

brown solid

Chemical Properties

The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.

Uses

2-Chloro-4-aminotoluene has been used in the preparation of 2-chloro-4-cyanotoluene by Sandmeyer reaction with cuprous cyanide.

Definition

ChEBI: A monochloroaniline that is p-toluidine in which one of the hydrogens that is meta to the amino group is replaced by a chlorine.

General Description

Brown solid with a mild odor.

Air & Water Reactions

May be sensitive to prolonged exposure to air and light. Insoluble in water.

Reactivity Profile

3-Chloro-4-methylaniline may be sensitive to prolonged exposure to air and light. 3-Chloro-4-methylaniline may react with oxidizing agents. 3-Chloro-4-methylaniline is incompatible with acids, acid chlorides, acid anhydrides and chloroformates. 3-Chloro-4-methylaniline is also incompatible with reducing agents.

Fire Hazard

3-Chloro-4-methylaniline is combustible.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl and NOx. See also other chloro toluidme entries.

Synthesis

2-Chloro-4-nitrotoluene

121-86-8

3-Chloro-4-methylaniline

95-74-9

General procedure for the synthesis of 3-chloro-p-toluidine from 2-chloro-4-nitrotoluene: General method: Nitro compounds (1 eq.), hexafluoroisopropanol (HFIP, 10 eq.) and iron powder (5 eq.) were added to the reaction tube and mixed. Subsequently, a 2N aqueous hydrochloric acid solution was slowly added to the reaction mixture. The reaction mixture was stirred at room temperature for 30 minutes and then neutralized with saturated aqueous sodium bicarbonate (NaHCO3) solution. Next, it was extracted three times with saturated aqueous sodium bicarbonate solution. The organic layers were combined, washed with brine, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. Finally, the crude product was purified by silica gel column chromatography to obtain the target product 3-chloro-p-toluidine.

Potential Exposure

Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.

Shipping

UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials

Incompatibilities

Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.

References

[1] Journal of the American Chemical Society, 2017, vol. 139, # 47, p. 17089 - 17097
[2] Tetrahedron Letters, 2017, vol. 58, # 37, p. 3646 - 3649
[3] Chemische Berichte, 1884, vol. 17, p. 534
[4] Recueil des Travaux Chimiques des Pays-Bas, 1932, vol. 51, p. 98,109
[5] Chem. Zentralbl., 1910, vol. 81, # I, p. 260

3-Chloro-4-methylaniline synthesis

121-86-8
95-74-9
Synthesis of 3-Chloro-4-methylaniline from 2-Chloro-4-nitrotoluene

3-Chloro-4-methylaniline Preparation Products And Raw materials

Raw materials

Sodium sulfide Ferric chloride Storage sump 4-Nitrotoluene Iron
2-Chloro-4-nitrotoluene 1-(bromomethyl)-2-chloro-4-nitrobenzene Sodium bicarbonate 1,1,1,3,3,3-Hexafluoro-2-propanol 3-CHLORO-N-METHYLANILINE

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Preparation Products

2-Amino-4-chloro-5-methylbenzenesulfonic acid 3-CHLORO-4-METHYLACETANILIDE 2-Chloro-4-fluorotoluene 4-Amino-2-chlorobenzaldehyde 3-Chloro-4-methylphenyl isocyanate
2-CHLORO-4-IODOTOLUENE 3,6-diamino-9(10)-acridone N,N-Dimethylcarbamic acid 2,6-Difluoro-N-(3-chloro-4-methylphenyl)benzamide, 97%

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3-Chloro-4-methylaniline Suppliers

Global( 304)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5225 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21586 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29812 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Shanghai Worldyang Chemical Co.,Ltd. 		+86-021-56795779 +8613651600618 sales@worldyachem.com China 967 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8615060885618 sales@amoychem.com China 6366 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co,.LTD 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Shanghai Worldyang Chemical Co.,Ltd. 		58
Xiamen AmoyChem Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from 3-Chloro-4-methylaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Chloro-4-methylaniline pictures 2026-05-28 3-Chloro-4-methylaniline
95-74-9
 $9.00 1KG 99.9 1 ton Hebei Chuanghai Biotechnology Co,.LTD
3-Chloro-4-methylaniline pictures 2019-09-02 3-Chloro-4-methylaniline
95-74-9
 $1.00 1KG 98% 200kg Career Henan Chemical Co

3-Chloro-4-methylaniline Spectrum

3-Chloro-4-methylaniline(95-74-9)MS3-Chloro-4-methylaniline(95-74-9)1HNMR3-Chloro-4-methylaniline(95-74-9)13CNMR3-Chloro-4-methylaniline(95-74-9)IR1

95-74-9(3-Chloro-4-methylaniline)Related Search:

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Methylparaben Methanol Methyl acetate N,N-Dimethyl-p-toluidine Basic Violet 1
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3-amino-2-chlorotoluene 3-CHLORO-P-TOLUIDINE 3-cpt 3-CHLORO-4-METHYLANILINE 3-chloro-4-methyl-benzenamine AKOS BBS-00003549 4-AMINO-2-CHLOROTOLUENE 1-AMINO-3-CHLORO-4-METHYLBENZENE 2-CHLORO-4-TOLUIDINE 2-CHLORO-4-AMINOTOLUENE OCPT O-CHLORO-P-TOLUIDINE 2-CHLORO-4-AMINOTOLUENE, 99+% (3-CHLORO-4-METHYLANILINE) 3-CHLORO-4-METHYLANILINE PESTANAL 3-CHLORO-4-METHYL-PHENYLAMINE O-CHLORO PARATOLUIDINE Benzenamine, 3-chloro-4-methyl- 2B OIL,4-AMINO-2-CHLOROTOLUENE starlicide 3-CHLORO-PARA-TOLUIDINE 3-CHLORO-4-TOLUIDINE 3-CHLORO-4-METHYLBENZAMINE 3-Chlor-4-methylanilin 3-CHLORO-4-METHYLANILINE / 4-AMINO-2-CHLOROTOLUENE 3-CHLORO-4-METHYLANILINE 99% 3-Chloro-4-methylaniline, 3-Chloro-p-toluidine, 4-Amino-2-chlorotoluene 3-Chloro-p-toluidine, 4-Amino-2-chlorotoluene TIMTEC-BB SBB004152 1-amino-3-chloro-4-methylenzene[qr] 2-chloro-4-aminotoluene[qr] 3-chloro-4-methylaniline[qr] 3-chloro-4-methyl-benzenamin 3-chloro-4-methylbenzenamine[qr] 3-chloro-p-toluidin Gull Toxicant P-CHLOROTOLUIDINE 3-Chloro-4-methylaniline,99% 4-Methyl-3-chloroaniline 4-methyl-3-chloroaniline[qr] benzenamine,3-chloro-4-methyl-[qr] cpt[qr] DKC 1347 dkc1347[qr] DRC 1339 drc1339[qr] drc1347 NCI-C02040 nci-c02040[qr] nsc96620[qr] p-Toluidine, 3-chloro- starlicide[qr] 3-Chloro-4-methylani 2B oil 3-Chloro-4-Methylaniline, 99% 250GR 4-Amino-2-chlorotoluene 3-Chloro-p-toluidine 3-Chloro-4-Met 3-Chloro-4-methylaniline > 3-Chloro-4-methylanilineSolution,1000mg/L,1ml