ChemicalBook >> CAS DataBase List >>7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)-

7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)-

CAS No.
1658474-60-2
Chemical Name:
7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)-
Synonyms
Talaromycesone A;(8S,8aS,15aR,15bR,16S)-16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-7H-8,15b-methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e′]bis[2]benzopyran-3,7,12-trione;7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)-
CBNumber:
CB59018443
Molecular Formula:
C29H24O11
Molecular Weight:
548.49
MDL Number:
MFCD33021595
MOL File:
1658474-60-2.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24

7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)- Properties

Boiling point 880.9±65.0 °C(Predicted)
Density 1.67±0.1 g/cm3(Predicted)
storage temp. -20°C
form A solid
pka 7.21±0.60(Predicted)

7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 32932 Talaromycesone A ≥95% 1658474-60-2 1mg $255 2026-04-30 Buy
Cayman Chemical 32932 Talaromycesone A ≥95% 1658474-60-2 5mg $948 2026-04-30 Buy
Biosynth IRC47460 Talaromycesone A 1658474-60-2 5mg $1434.3 2026-06-04 Buy
Biosynth IRC47460 Talaromycesone A 1658474-60-2 10mg $2294.9 2026-06-04 Buy
Biosynth IRC47460 Talaromycesone A 1658474-60-2 25mg $4302.75 2026-06-04 Buy
Product number Packaging Price Buy
32932 1mg $255 Buy
32932 5mg $948 Buy
IRC47460 5mg $1434.3 Buy
IRC47460 10mg $2294.9 Buy
IRC47460 25mg $4302.75 Buy

7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)- Chemical Properties, Uses, Production

Uses

Talaromycesone A is an oxaphenalenone dimer compound. Talaromycesone A exhibits potent antibacterial activities with an IC50 of 3.70 μM, against human pathogenic Staphylococcus strains. Talaromycesone A displays potent acetylcholinesterase inhibitory activities with an IC50 of 7.49 μM[1].

Biological Activity

Talaromycesone A is a fungal metabolite originally isolated from Talaromyces.1 It is active against S. epidermidis and methicillin-resistant S. aureus (MRSA) bacteria (IC50s = 3.70 and 5.48 μM, respectively). Talaromycesone A inhibits acetylcholinesterase (AChE) in a cell-free assay (IC50 = 7.49 μM for the human enzyme).

References

1.Wu, B., Ohlendorf, B., Oesker, V., et al.Acetylcholinesterase inhibitors from a marine fungus Talaromyces sp. strain LF458Mar. Biotechnol. (NY)17(1)110-119(2015)

7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)- Preparation Products And Raw materials

Raw materials

Preparation Products

7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)- Suppliers

Global Suppliers ( 11)
Supplier Tel Email Country ProdList Advantage
ChemeGen 18818260767 2625930290@qq.com China 6966 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1246 58
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 13120558703 sales@scrbio.com China 9876 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Shanghai Weiyite Biotechnology Co., Ltd 15317051735 zhaojing@wytsci.com China 10000 58

1658474-60-2 (7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)-) Related Search:

7H-8,15b-Methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e']bis[2]benzopyran-3,7,12-trione, 16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-, (8S,8aS,15aR,15bR,16S)- Talaromycesone A (8S,8aS,15aR,15bR,16S)-16-(acetyloxy)-8,8a,15,15a-tetrahydro-4,11,14-trihydroxy-8a-methoxy-6,9-dimethyl-7H-8,15b-methano-1H,3H,12H-benzo[de]cyclohepta[1,2-g:3,4,5-d'e′]bis[2]benzopyran-3,7,12-trione 1658474-60-2