ChemicalBook >> CAS DataBase List >>Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
![Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Structure](CAS/20211123/GIF/2245842-16-2.gif)
- CAS No.
- 2245842-16-2
- Chemical Name:
- Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- Synonyms
- 2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite;2’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-2’-fluoroinosine3’-CEDphosphoramidite;5’-O-(4,4-Dimethoxytrityl)-2’-fluoro-2’-deoxy inosine-3’-CED phosphoramidite;2’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-2’-fluoro inosine 3’-CED phosphoramidite;5'-O-(4，4'-Dimethoxytrityl)-2'-fluoro-2'-deoxyinosine-3'-cyanoethyl phosphoramidite;Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-(6-oxo-3,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- CBNumber:
- CB59021452
- Molecular Formula:
- C40H46FN6O7P
- Molecular Weight:
- 772.8
- MDL Number:
- MFCD22374068
- MOL File:
- 2245842-16-2.mol
- MSDS File:
- SDS
Last updated:2026-07-16 07:06:08
Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Properties
| Boiling point | 840.2±75.0 °C(Predicted) |
|---|---|
| storage temp. | 2-8°C, stored under nitrogen |
| solubility |
DMSO: Sparingly Soluble: 1-10 mg/ml Ethanol: Sparingly Soluble: 1-10 mg/ml |
| pka | 3.45±0.70(Predicted) |
| form | Solid |
| color | White to off-white |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 43369 | 2''-fluoro-5''-O-DMT-2''-Deoxyinosine-3''-CE Phosphoramidite ≥98%(mixtureofdiastereomers) | 2245842-16-2 | 25mg | $61 | 2026-04-30 | Buy |
| Cayman Chemical | 43369 | 2''-fluoro-5''-O-DMT-2''-Deoxyinosine-3''-CE Phosphoramidite ≥98%(mixtureofdiastereomers) | 2245842-16-2 | 50mg | $109 | 2026-04-30 | Buy |
| Cayman Chemical | 43369 | 2''-fluoro-5''-O-DMT-2''-Deoxyinosine-3''-CE Phosphoramidite ≥98%(mixtureofdiastereomers) | 2245842-16-2 | 100mg | $170 | 2026-04-30 | Buy |
| Cayman Chemical | 43369 | 2''-fluoro-5''-O-DMT-2''-Deoxyinosine-3''-CE Phosphoramidite ≥98%(mixtureofdiastereomers) | 2245842-16-2 | 250mg | $334 | 2026-04-30 | Buy |
| Biosynth | VPD84216 | 2'-Fluoro-5'-o-DMT-2'-deoxyinosine-3'-ce-phosphoramidite | 2245842-16-2 | 5g | $2500.85 | 2026-06-05 | Buy |
Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Chemical Properties, Uses, Production
Uses
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].
References
[1] Virág L, Szabó C. Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death. FASEB J. 2001 Jan;15(1):99-107. DOI:10.1096/fj.00-0299com
[2] Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res. 1988 Feb;23(2):143-50. DOI:10.1203/00006450-198802000-00001
[3] EUNJOO LEE. Submicron-sized hydrogels incorporating cyclic dinucleotides for selective delivery and elevated cytokine release in macrophages[J]. Acta Biomaterialia, 2016, 29: Pages 271-281. DOI: 10.1016/j.actbio.2015.10.025
Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Preparation Products And Raw materials
Raw materials
Preparation Products
Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Suppliers
Global Suppliers ( 20)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhu Huaren Science and Technology Co., Ltd. | 5842013 18155347026 | xujuan@hdpharm.com | China | 255 | 64 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Zhengzhou Granlen Sciences, ltd. | 0371-85513397 +86-18610099868 | info@granlen.com | China | 1890 | 58 |
| NewCan Biotech Limited | +86-571-86912261 19975279805 | sales@newcanbio.com | China | 9984 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai shuodian Biotechnology Co., Ltd | 18221553137 | ddwuyu@126.com | China | 1071 | 58 |
| Panaishen (Henan) Pharmaceutical Science and Technology Co. , Ltd. | 0371-65325800 13700860222 | haifeng.zhang@pannacean.com | China | 1703 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39319 | 58 |
View Latest Price from Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | 2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
2245842-16-2
|
10g | TargetMol Chemicals Inc. |
-
- 2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
2245842-16-2
- TargetMol Chemicals Inc.
Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Spectrum
2245842-16-2 (Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]) Related Search:
2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite
5'-Dimethoxytrityl-N-p-isopropyl-phenoxyacetyl-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-hexadecyl-N-(2-methyl-1-oxopropyl)-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
NA
(E)-N'-{9-[(1R,3R,4R,7S)-1-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-7-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-N,N-dimethylmethanimidamide
1of2
2’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-2’-fluoro inosine 3’-CED phosphoramidite
(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-(6-oxo-3,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
2’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-2’-fluoroinosine3’-CEDphosphoramidite
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite
5'-O-(4，4'-Dimethoxytrityl)-2'-fluoro-2'-deoxyinosine-3'-cyanoethyl phosphoramidite
5’-O-(4,4-Dimethoxytrityl)-2’-fluoro-2’-deoxy inosine-3’-CED phosphoramidite
Inosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
2245842-16-2
C40H46FN6O7P
