2-(6-Aminopurin-9-yl)ethanol
- CAS No.
- 707-99-3
- Chemical Name:
- 2-(6-Aminopurin-9-yl)ethanol
- Synonyms
- Adefovir Impurity 5 CRS;6-AMINO-9H-PURIN-9-ETHANOL;9-(2-hydroxyethyl) adenine;Tenofovir Ethanol Impurity;9-(2-Hydroxyethyl)adenine>2-(6-AMINOPURIN-9-YL)ETHANOL;9H-Purine-9-ethanol, 6-amino-;2-(6-azanylpurin-9-yl)ethanol;Tenofovirdisoproxil Impurity 39;6-Amino-9-(2-hydroxyethyl)purine
- CBNumber:
- CB5947254
- Molecular Formula:
- C7H9N5O
- Molecular Weight:
- 179.18
- MDL Number:
- MFCD04220770
- MOL File:
- 707-99-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 9-(2-Hydroxyethyl)adenine >98.0%(HPLC)(T) | H1290 | 5g | $51 |
| 9-(2-Hydroxyethyl)adenine >98.0%(HPLC)(T) | H1290 | 25g | $149 |
| 2-(6-Aminopurin-9-yl)ethanol | A628908 | 50mg | $50 |
| 2-(6-Aminopurin-9-yl)ethanol | A628908 | 100mg | $70 |
| 9-(2-Hydroxyethyl)adenine | J57185 | 1g | $15 |
| More product size | |||
| Melting point | 240.0 to 244.0 °C |
|---|---|
| Boiling point | 473.2±55.0 °C(Predicted) |
| Density | 1.67±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated) |
| pka | 14.35±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 10g/L at 20℃ |
| λmax | 261nm(H2O)(lit.) |
| InChIKey | VAQOTZQDXZDBJK-UHFFFAOYSA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| HS Code | 2933.99.8290 | |||||||||
| NFPA 704 |
|
2-(6-Aminopurin-9-yl)ethanol price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H1290 | 9-(2-Hydroxyethyl)adenine >98.0%(HPLC)(T) | 707-99-3 | 5g | $51 | 2026-04-30 | Buy |
| TCI Chemical | H1290 | 9-(2-Hydroxyethyl)adenine >98.0%(HPLC)(T) | 707-99-3 | 25g | $149 | 2026-04-30 | Buy |
| TRC | A628908 | 2-(6-Aminopurin-9-yl)ethanol | 707-99-3 | 50mg | $50 | 2021-12-16 | Buy |
| TRC | A628908 | 2-(6-Aminopurin-9-yl)ethanol | 707-99-3 | 100mg | $70 | 2021-12-16 | Buy |
| AK Scientific | J57185 | 9-(2-Hydroxyethyl)adenine | 707-99-3 | 1g | $15 | 2021-12-16 | Buy |
2-(6-Aminopurin-9-yl)ethanol Chemical Properties,Uses,Production
Uses
2-(6-Aminopurin-9-yl)ethanol is a useful intermediate in the preparation of aryloxyalkyl derivatives of adenine with antiviral activity.
Synthesis
96-49-1
66224-66-6
707-99-3
Example 5 Preparation of 9-(2-hydroxyethyl)adenine (5) A mechanical stirrer, condenser tube, thermometer and heating jacket were assembled on a 12L three-necked round bottom flask. After the system was replaced by nitrogen, adenine (504 g), vinyl carbonate (343 g), N,N-dimethylformamide (DMF, 3.7 L) and sodium hydroxide (7.80 g) were added sequentially. Stirring was turned on and the mixture was heated to reflux (about 80 min to reach reflux, reactor internal temperature 145°C) and the reflux reaction was maintained for 2 hours. The heating jacket was removed and the yellow reaction solution was allowed to cool naturally to below 100°C. The mixture was then cooled to 5 °C in an ice bath and diluted with the addition of toluene (3.8 L). The temperature of the reaction system was kept below 10 °C and the stirring was continued for 2 hours and then filtered. The filter cake was washed sequentially with toluene (2 x 0.5 L) and pre-cooled ethanol (1.5 L), and finally dried under reduced pressure conditions (-30 inches Hg) at 50 °C for 14 h to constant weight. The resulting product 5 was characterized for purity and structure by HPLC and 1H-NMR (DMSO-d6).
References
[1] Patent: CN106699814, 2017, A. Location in patent: Paragraph 0020-0021
[2] Molecules, 2012, vol. 17, # 11, p. 13290 - 13306
[3] Patent: US2003/225277, 2003, A1. Location in patent: Page 10-11
[4] Tetrahedron Letters, 2006, vol. 47, # 11, p. 1767 - 1770
[5] Patent: CN104387421, 2016, B. Location in patent: Paragraph 0026-0028
2-(6-Aminopurin-9-yl)ethanol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +8618627948422 | sale@hdimpurity.com | China | 3681 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 10000 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15082 | 58 |
View Lastest Price from 2-(6-Aminopurin-9-yl)ethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-12 | Tenofovir impurity 39
707-99-3
|
US $0.00 / mg | 10mg | 0.98 | 5g | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
 |
2022-10-22 | 2-(6-Aminopurin-9-yl)ethanol
707-99-3
|
US $30.00-28.00 / Kg | 1Kg | 99.0% up | 50 tons per month | Xinxiang Hongqi District Houyuan Trading Co.,Ltd | |
 |
2019-09-05 | 2-(6-Aminopurin-9-yl)ethanol
707-99-3
|
US $1.00 / KG | 1KG | 98% | 1000KG | Career Henan Chemical Co |
-
- Tenofovir impurity 39
707-99-3
- US $0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- 2-(6-Aminopurin-9-yl)ethanol
707-99-3
- US $30.00-28.00 / Kg
- 99.0% up
- Xinxiang Hongqi District Houyuan Trading Co.,Ltd
-
- 2-(6-Aminopurin-9-yl)ethanol
707-99-3
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
