ChemicalBook >> CAS DataBase List >>L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]-

L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]-

L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]- structure

CAS No.: 1262034-38-7

Chemical Name:: L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]-

Synonyms: UNII-SOA52D3NLL;Dacomitinib metabolite M2;Dacomitinib cysteine conjugate;L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]-

CBNumber:: CB59767934

Molecular Formula:: C27H32ClFN6O4S

Molecular Weight:: 591.1

MDL Number:

MOL File:: 1262034-38-7.mol

Last updated:2025-04-18 09:51:13

Request For Quotation

L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]- Properties

Boiling point	798.9±60.0 °C(Predicted)
Density	1.412±0.06 g/cm3(Predicted)
pka	2.04±0.10(Predicted)
FDA UNII	SOA52D3NLL

L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]- Chemical Properties, Uses, Production

Uses

Dacomitinib metabolite M1/2 is a potent inhibitor of both wild-type (WT) EGFR and the T790M mutation, demonstrating significant activity against acquired resistance mechanisms in EGFR-mutant non-small-cell lung cancer (NSCLC).

References

[1] Dacomitinib in lung cancer: a "lost generation" EGFR tyrosine-kinase inhibitor from a bygone era DOI:10.2147/DDDT.S52787

L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]- Suppliers

Global Suppliers ( 2)

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TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

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1262034-38-7 (L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]-) Related Search:

EGFR Protein, HUMAN (621A.A, HEK293, FC) EGFR protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) HER2/CD340 protein, HUMAN (BIOTINYLATED, HEK293, HIS) HER3 Protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) Amivantamab

HER2/CD340 Protein, RAT (HEK293)

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L-Cysteine, S-[3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]amino]-3-oxo-1-(1-piperidinylmethyl)propyl]- Dacomitinib cysteine conjugate Dacomitinib metabolite M2 UNII-SOA52D3NLL 1262034-38-7 C27H32ClFN6O4S