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4-(Trifluoromethyl)benzamide

4-(Trifluoromethyl)benzamide Structure
4-(Trifluoromethyl)benzamide structure
CAS No.
1891-90-3
Chemical Name:
4-(Trifluoromethyl)benzamide
Synonyms
TIMTEC-BB SBB002331;p-Trifluoromethylbenzamide;4-Carbamoylbenzotrifluoride;à,à,à-trifluoro-p-toluamide;4-(TRIFLUOROMETHYL)BENZAMIDE;N-(4-Trifluoromethyl)benzamide;4-(Trifluoromethyl)benzamide99%;Benzamide, 4-(trifluoromethyl)-;4-(TRIFLUOROMETHYL)BENZAMIDE 99%;4-(Trifluoromethyl)benzamide, 98+%
CBNumber:
CB6105480
Molecular Formula:
C8H6F3NO
Molecular Weight:
189.13
MDL Number:
MFCD00007998
MOL File:
1891-90-3.mol
MSDS File:
SDS
Last updated:2026-05-28 04:48:22
Product description Number Pack Size Price
4-(Trifluoromethyl)benzamide T3474 5G $44
4-(Trifluoromethyl)benzamide T3474 25G $151
4-(Trifluoromethyl)benzamide 99% PC7507 5g $21
4-(Trifluoromethyl)benzamide 99% PC7507 25g $28
4-(Trifluoromethyl)benzamide 99% PC7507 100g $88
More product size
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4-(Trifluoromethyl)benzamide Properties

Melting point 184-186 °C(lit.)
Boiling point 254.2±40.0 °C(Predicted)
Density 1.3305 (estimate)
storage temp. Sealed in dry,Room Temperature
pka 15.36±0.50(Predicted)
form powder to crystal
color White to Almost white
BRN 2098929
CAS DataBase Reference 1891-90-3(CAS DataBase Reference)
FDA UNII CTD99SHH2S
NIST Chemistry Reference 4-CF3-C6H4CONH2(1891-90-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280g-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  2924297099
NFPA 704
1
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4-(Trifluoromethyl)benzamide price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T3474 4-(Trifluoromethyl)benzamide 1891-90-3 5G $44 2026-04-30 Buy
TCI Chemical T3474 4-(Trifluoromethyl)benzamide 1891-90-3 25G $151 2025-07-31 Buy
Apolloscientific PC7507 4-(Trifluoromethyl)benzamide 99% 1891-90-3 5g $21 2026-06-04 Buy
Apolloscientific PC7507 4-(Trifluoromethyl)benzamide 99% 1891-90-3 25g $28 2026-06-04 Buy
Apolloscientific PC7507 4-(Trifluoromethyl)benzamide 99% 1891-90-3 100g $88 2026-06-04 Buy
Product number Packaging Price Buy
T3474 5G $44 Buy
T3474 25G $151 Buy
PC7507 5g $21 Buy
PC7507 25g $28 Buy
PC7507 100g $88 Buy

4-(Trifluoromethyl)benzamide Chemical Properties,Uses,Production

Chemical Properties

White to light yellow crystal powde

Synthesis

alpha,alpha,alpha-Trifluoro-o-toluoyl chloride

329-15-7

4-(Trifluoromethyl)benzamide

1891-90-3

Synthesis of compound C: Ammonia (2 mL) was slowly added dropwise to 4-trifluoromethylbenzoyl chloride (417 mg, 2 mmol) at room temperature while maintaining stirring. After the reaction continued for 3 h, the completion of the reaction was confirmed by thin layer chromatography (TLC, unfolding agent ratio of ethyl acetate:hexane = 1:2). The reaction mixture was poured into water (10 mL) and subsequently extracted with ethyl acetate (10 mL x 3). The combined ethyl acetate layers were washed sequentially with water (10 mL × 2) and saturated saline (10 mL), dried over anhydrous magnesium sulfate and filtered. The filtrate was distilled under reduced pressure to remove the solvent to give the crude product (355 mg, 2.0 mmol). The crude product was purified by solvent recrystallization from ethyl acetate/hexane mixture to give compound C (white needle-like crystals, 359 mg) in 95% yield. The melting point of the product was 186.5-187.5 °C. 1H-NMR (300 MHz, DMSO-d6) δ: 7.63, 8.19 (both broad peaks, 1H, NH or OH), 8.06 (double peak, 2H, J = 8.0 Hz, Ar-H), 7.84 (double peak, 2H, J = 8.0 Hz, Ar-H).

References

[1] Organic Process Research and Development, 2007, vol. 11, # 6, p. 1010 - 1014
[2] Patent: EP2070908, 2009, A1. Location in patent: Page/Page column 9; 13
[3] Journal of Medicinal Chemistry, 2008, vol. 51, # 8, p. 2400 - 2411
[4] Synthetic Communications, 2010, vol. 40, # 23, p. 3538 - 3543
[5] Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1957, vol. 23, p. 634

4-(Trifluoromethyl)benzamide Preparation Products And Raw materials

Raw materials

4-(Trifluoromethyl)benzaldehyde Trifluoro-p-tolunitrile Cobalt, octacarbonyldi-, (Co-Co) alpha,alpha,alpha-Trifluoro-o-toluoyl chloride 4-Iodobenzotrifluoride
4-Bromobenzotrifluoride Ammonia

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Preparation Products

2-Aminobenzotrifluoride

4-(Trifluoromethyl)benzamide Suppliers

Global( 147)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 52513593@qq.com CHINA 2972 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10000 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Supplier Advantage
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
career henan chemical co 		58
Nanjing Dolon Biotechnology Co.,Ltd. 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Fuxin Pharmaceutical 		58
SIMAGCHEM CORP 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58

View Lastest Price from 4-(Trifluoromethyl)benzamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(Trifluoromethyl)benzamide pictures 2025-06-27 4-(Trifluoromethyl)benzamide
1891-90-3
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
4-(Trifluoromethyl)benzamide pictures 2025-06-20 4-(Trifluoromethyl)benzamide
1891-90-3
 $1.00-20.00 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
4-(Trifluoromethyl)benzamide pictures 2019-07-06 4-(Trifluoromethyl)benzamide
1891-90-3
 $3.00 1KG 99% 100kg Career Henan Chemical Co

4-(Trifluoromethyl)benzamide Spectrum

4-(Trifluoromethyl)benzamide(1891-90-3)1HNMR

1891-90-3(4-(Trifluoromethyl)benzamide)Related Search:

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4-(Trifluoromethyl)benzoic acid 2-(Trifluoromethyl)benzoic acid 4-Aminobenzotrifluoride 4-(Trifluoromethyl)cinnamic acid 4-(Trifluoromethyl)benzene-1-sulfonyl chloride
Trifluoro-p-tolunitrile 1-[(AMMONIOOXY)METHYL]-4-(TRIFLUOROMETHYL)BENZENE CHLORIDE 4-(Trifluoromethoxy)benzonitrile 4-(Trifluoromethoxy)phenylhydrazine hydrochloride 4-(TRIFLUOROMETHYL)BENZHYDRAZIDE
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Benzamide, 4-(trifluoromethyl)- N-(4-Trifluoromethyl)benzamide p-Trifluoromethylbenzamide 4-(TRIFLUOROMETHYL)BENZAMIDE TIMTEC-BB SBB002331 4-(Trifluoromethyl)Benzamide p-(Trifluoromethyl)Benzamide 4-(TRIFLUOROMETHYL)BENZAMIDE 99% 4-(Trifluoromethyl)benzamide, 98+% à,à,à-trifluoro-p-toluamide 4-(Trifluoromethyl)benzamide99% 4-Carbamoylbenzotrifluoride 1891-90-3 CF3C6H4CONH2 C8H6NOF3 C8H6F3NO Organic Building Blocks Building Blocks Amides Carbonyl Compounds Fluorine series