2-FLUORO-6-NITRO-PHENYLAMINE
- CAS No.
- 17809-36-8
- Chemical Name:
- 2-FLUORO-6-NITRO-PHENYLAMINE
- Synonyms
- Einecs 241-779-9;2-FLUORO-6-NITROANILINE;2-Nitro-6-fluoroaniline;2-Fluoro-6-nitroaniline98%;2-Fluoro-6-nitroaniline 98%;6-AMino-2-Fluoronitrobenzene;2-Amino-3-fluoronitrobenzene;2-FLUORO-6-NITRO-PHENYLAMINE;Benzenamine, 2-fluoro-6-nitro-;2-FLUORO-6-NITRO-PHENYLAMINE ISO 9001：2015 REACH
- CBNumber:
- CB6109998
- Molecular Formula:
- C6H5FN2O2
- Molecular Weight:
- 156.11
- MDL Number:
- MFCD04112583
- MOL File:
- 17809-36-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Fluoro-6-nitroaniline | B434828 | 1g | $50 |
| 2-Fluoro-6-nitroaniline | CS-D0998 | 5g | $57 |
| 2-Fluoro-6-nitroaniline 95+% | 074086 | 1g | $60 |
| 2-Fluoro-6-nitroaniline 97% | PC10555 | 5g | $93 |
| 2-Fluoro-6-nitroaniline | CS-D0998 | 10g | $100 |
| More product size | |||
| Melting point | 74-75 |
|---|---|
| Boiling point | 271.5±20.0 °C(Predicted) |
| Density | 1.448±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | -1.76±0.25(Predicted) |
| form | solid |
| color | Yellow/orange |
| InChI | InChI=1S/C6H5FN2O2/c7-4-2-1-3-5(6(4)8)9(10)11/h1-3H,8H2 |
| InChIKey | BHWHYGWMNMCXBA-UHFFFAOYSA-N |
| SMILES | C1(N)=C([N+]([O-])=O)C=CC=C1F |
| CAS DataBase Reference | 17809-36-8(CAS DataBase Reference) |
| FDA UNII | E347K77NR4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| Hazard Codes | Xi |
| Hazard Note | Irritant |
| HS Code | 29214990 |
2-FLUORO-6-NITRO-PHENYLAMINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B434828 | 2-Fluoro-6-nitroaniline | 17809-36-8 | 1g | $50 | 2021-12-16 | Buy |
| ChemScene | CS-D0998 | 2-Fluoro-6-nitroaniline | 17809-36-8 | 5g | $57 | 2021-12-16 | Buy |
| Matrix Scientific | 074086 | 2-Fluoro-6-nitroaniline 95+% | 17809-36-8 | 1g | $60 | 2021-12-16 | Buy |
| Apolloscientific | PC10555 | 2-Fluoro-6-nitroaniline 97% | 17809-36-8 | 5g | $93 | 2021-12-16 | Buy |
| ChemScene | CS-D0998 | 2-Fluoro-6-nitroaniline | 17809-36-8 | 10g | $100 | 2021-12-16 | Buy |
2-FLUORO-6-NITRO-PHENYLAMINE Chemical Properties,Uses,Production
Chemical Properties
light yellow powder
Uses
2-Fluoro-6-nitro-phenylamine is mainly used as a pharmaceutical intermediate for the synthesis of specific drug molecules, such as anti-tumor drugs, antibacterial agents, etc.
Synthesis
342-52-9
17809-36-8
General procedure for the synthesis of 2-fluoro-6-nitroaniline from N-(2-fluoro-6-nitrophenyl)acetamide: 3 g (0.0151 mol) of N-(2-fluoro-6-nitrophenyl)acetamide (3a) was dissolved in 30 mL of concentrated H2SO4 and the reaction was stirred for 2 hr at 50 °C. After completion of the reaction, it was cooled to room temperature and the reaction solution was slowly poured into an ice bath and a large amount of precipitate was observed to be generated. The precipitate was collected by filtration and the acidic aqueous solution was extracted with ether. Purification by fast column chromatography afforded the target compound 2-fluoro-6-nitroaniline in 74% yield. The melting point of the product was 47-48 °C. 1H NMR (DMSO-d6) data: δ 7.82 (d, 1H, J=8.8 Hz, H-5), 7.42 (m, 1H, H-3), 7.25 (s, 2H, NH2), 6.63 (m, 1H, H-4). GC/MS analysis showed the molecular ion peak as 157 (M+H). Elemental analysis (C6H5FN2O2) Calculated values: C, 46.16; H, 3.23; F, 12.17; N, 17.94. Measured values: C, 46.18; H, 3.27; F, 12.15; N, 17.98.
References
[1] European Journal of Medicinal Chemistry, 2019, vol. 161, p. 399 - 415
[2] Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1976, vol. 30, p. 141 - 149
2-FLUORO-6-NITRO-PHENYLAMINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
View Lastest Price from 2-FLUORO-6-NITRO-PHENYLAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 2-FLUORO-6-NITRO-PHENYLAMINE
17809-36-8
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-09-25 | 2-FLUORO-6-NITRO-PHENYLAMINE
17809-36-8
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2020-02-26 | 2-Fluoro-6-nitroaniline
17809-36-8
|
US $0.00-0.00 / KG | 1KG | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 2-FLUORO-6-NITRO-PHENYLAMINE
17809-36-8
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-FLUORO-6-NITRO-PHENYLAMINE
17809-36-8
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Fluoro-6-nitroaniline
17809-36-8
- US $0.00-0.00 / KG
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
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